6AB0

Crystal structure of Methanosarcina mazei PylRS(Y306A/Y384F) complexed with pAmPyLys

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000049	molecular_function	tRNA binding
A	0004812	molecular_function	aminoacyl-tRNA ligase activity
A	0005524	molecular_function	ATP binding
A	0043039	biological_process	tRNA aminoacylation

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue MG A 501

Chain	Residue
A	ATP504
A	HOH655
A	HOH663
A	HOH728
A	HOH730

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site_id	AC2
Number of Residues	6
Details	binding site for residue MG A 502

Chain	Residue
A	HOH657
A	HOH747
A	GLU396
A	SER399
A	MG503
A	ATP504

---

site_id	AC3
Number of Residues	6
Details	binding site for residue MG A 503

Chain	Residue
A	GLU396
A	MG502
A	ATP504
A	HOH657
A	HOH775
A	HOH791

---

site_id	AC4
Number of Residues	29
Details	binding site for residue ATP A 504

Chain	Residue
A	ARG330
A	GLU332
A	HIS338
A	LEU339
A	PHE342
A	MET344
A	GLU396
A	LEU397
A	SER398
A	SER399
A	GLY421
A	GLY423
A	ARG426
A	MG501
A	MG502
A	MG503
A	9UF505
A	HOH625
A	HOH642
A	HOH655
A	HOH657
A	HOH663
A	HOH728
A	HOH730
A	HOH738
A	HOH747
A	HOH764
A	HOH775
A	HOH804

---

site_id	AC5
Number of Residues	13
Details	binding site for residue 9UF A 505

Chain	Residue
A	MET300
A	ALA302
A	ARG330
A	MET344
A	ASN346
A	CYS348
A	PHE384
A	ASP408
A	TRP417
A	GLY419
A	GLY421
A	ATP504
A	HOH665

---

site_id	AC6
Number of Residues	6
Details	binding site for residue K A 506

Chain	Residue
A	LEU202
A	ASN203
A	ASP206
A	HOH606
A	HOH783
A	HOH853

---

site_id	AC7
Number of Residues	3
Details	binding site for residue K A 507

Chain	Residue
A	GLU341
A	ARG442
A	HOH799

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site_id	AC8
Number of Residues	3
Details	binding site for residue K A 508

Chain	Residue
A	GLY335
A	HIS338
A	LYS438

---

site_id	AC9
Number of Residues	4
Details	binding site for residue PO4 A 509

Chain	Residue
A	GLU240
A	ARG252
A	HOH740
A	HOH760

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