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6A7I

CYP154C4 from Streptomyces sp. W2061

Functional Information from GO Data
ChainGOidnamespacecontents
A0004497molecular_functionmonooxygenase activity
A0005506molecular_functioniron ion binding
A0006707biological_processcholesterol catabolic process
A0008395molecular_functionsteroid hydroxylase activity
A0016491molecular_functionoxidoreductase activity
A0016705molecular_functionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
A0020037molecular_functionheme binding
A0036199molecular_functioncholest-4-en-3-one 26-monooxygenase activity
A0046872molecular_functionmetal ion binding
Functional Information from PDB Data
site_idAC1
Number of Residues20
Detailsbinding site for residue HEM A 501
ChainResidue
ALYS57
AVAL288
AARG291
APHE314
AALA342
APHE343
AHIS348
ACYS350
APRO351
ASER356
AHOH637
AMET86
AHOH644
ALEU87
AHIS94
AARG98
ALEU105
ALEU234
AILE235
ATHR242

Functional Information from PROSITE/UniProt
site_idPS00086
Number of Residues10
DetailsCYTOCHROME_P450 Cytochrome P450 cysteine heme-iron ligand signature. FGhGPHVCPG
ChainResidueDetails
APHE343-GLY352

218500

PDB entries from 2024-04-17

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