6A5I
Pseudocerastes Persicus Trypsin Inhibitor
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004867 | molecular_function | serine-type endopeptidase inhibitor activity |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005615 | cellular_component | extracellular space |
| A | 0015459 | molecular_function | potassium channel regulator activity |
| A | 0030414 | molecular_function | peptidase inhibitor activity |
| A | 0044483 | biological_process | venom-mediated perturbation of hemostasis |
| A | 0090729 | molecular_function | toxin activity |
| A | 0099106 | molecular_function | ion channel regulator activity |
Functional Information from PROSITE/UniProt
| site_id | PS00280 |
| Number of Residues | 19 |
| Details | BPTI_KUNITZ_1 Pancreatic trypsin inhibitor (Kunitz) family signature. FiyGGCggnannFetraeC |
| Chain | Residue | Details |
| A | PHE35-CYS53 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 50 |
| Details | Domain: {"description":"BPTI/Kunitz inhibitor","evidences":[{"source":"PROSITE-ProRule","id":"PRU00031","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Site: {"description":"May be the major determinant of the binding affinity for potassium channels","evidences":[{"source":"PubMed","id":"30973886","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Site: {"description":"Reactive bond for trypsin","evidences":[{"source":"UniProtKB","id":"P31713","evidenceCode":"ECO:0000250"},{"source":"PubMed","id":"30973886","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
