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6A45

Structure of mouse TREX2

Functional Information from GO Data
ChainGOidnamespacecontents
A0000287molecular_functionmagnesium ion binding
A0003676molecular_functionnucleic acid binding
A0004527molecular_functionexonuclease activity
A0005634cellular_componentnucleus
A0005737cellular_componentcytoplasm
A0006259biological_processDNA metabolic process
A0006281biological_processDNA repair
A0006308biological_processDNA catabolic process
A0008296molecular_function3'-5'-DNA exonuclease activity
A0008311molecular_functiondouble-stranded DNA 3'-5' DNA exonuclease activity
A0008408molecular_function3'-5' exonuclease activity
A0042803molecular_functionprotein homodimerization activity
A0046872molecular_functionmetal ion binding
B0000287molecular_functionmagnesium ion binding
B0003676molecular_functionnucleic acid binding
B0004527molecular_functionexonuclease activity
B0005634cellular_componentnucleus
B0005737cellular_componentcytoplasm
B0006259biological_processDNA metabolic process
B0006281biological_processDNA repair
B0006308biological_processDNA catabolic process
B0008296molecular_function3'-5'-DNA exonuclease activity
B0008311molecular_functiondouble-stranded DNA 3'-5' DNA exonuclease activity
B0008408molecular_function3'-5' exonuclease activity
B0042803molecular_functionprotein homodimerization activity
B0046872molecular_functionmetal ion binding
Functional Information from PDB Data
site_idAC1
Number of Residues7
Detailsbinding site for residue PO4 A 301
ChainResidue
AGLY135
AHIS137
AGLY166
AARG167
AARG178
ATYR179
AHOH414

site_idAC2
Number of Residues5
Detailsbinding site for residue PO4 A 302
ChainResidue
ATRP219
AALA220
AHOH408
AHIS137
ALEU138

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsACT_SITE: Proton donor/acceptor => ECO:0000250
ChainResidueDetails
AHIS188
BHIS188

site_idSWS_FT_FI2
Number of Residues8
DetailsBINDING: BINDING => ECO:0000250
ChainResidueDetails
ATYR122
AASP193
BASP14
BGLU16
BTYR122
BASP193
AASP14
AGLU16

221051

PDB entries from 2024-06-12

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