6A3V

Complex structure of human 4-1BB and 4-1BBL

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005164	molecular_function	tumor necrosis factor receptor binding
A	0006955	biological_process	immune response
A	0016020	cellular_component	membrane
A	0032813	molecular_function	tumor necrosis factor receptor superfamily binding
C	0005164	molecular_function	tumor necrosis factor receptor binding
C	0006955	biological_process	immune response
C	0016020	cellular_component	membrane
C	0032813	molecular_function	tumor necrosis factor receptor superfamily binding
E	0005164	molecular_function	tumor necrosis factor receptor binding
E	0006955	biological_process	immune response
E	0016020	cellular_component	membrane
E	0032813	molecular_function	tumor necrosis factor receptor superfamily binding
G	0005164	molecular_function	tumor necrosis factor receptor binding
G	0006955	biological_process	immune response
G	0016020	cellular_component	membrane
G	0032813	molecular_function	tumor necrosis factor receptor superfamily binding
I	0005164	molecular_function	tumor necrosis factor receptor binding
I	0006955	biological_process	immune response
I	0016020	cellular_component	membrane
I	0032813	molecular_function	tumor necrosis factor receptor superfamily binding
K	0005164	molecular_function	tumor necrosis factor receptor binding
K	0006955	biological_process	immune response
K	0016020	cellular_component	membrane
K	0032813	molecular_function	tumor necrosis factor receptor superfamily binding
M	0005164	molecular_function	tumor necrosis factor receptor binding
M	0006955	biological_process	immune response
M	0016020	cellular_component	membrane
M	0032813	molecular_function	tumor necrosis factor receptor superfamily binding
O	0005164	molecular_function	tumor necrosis factor receptor binding
O	0006955	biological_process	immune response
O	0016020	cellular_component	membrane
O	0032813	molecular_function	tumor necrosis factor receptor superfamily binding
Q	0005164	molecular_function	tumor necrosis factor receptor binding
Q	0006955	biological_process	immune response
Q	0016020	cellular_component	membrane
Q	0032813	molecular_function	tumor necrosis factor receptor superfamily binding
S	0005164	molecular_function	tumor necrosis factor receptor binding
S	0006955	biological_process	immune response
S	0016020	cellular_component	membrane
S	0032813	molecular_function	tumor necrosis factor receptor superfamily binding
U	0005164	molecular_function	tumor necrosis factor receptor binding
U	0006955	biological_process	immune response
U	0016020	cellular_component	membrane
U	0032813	molecular_function	tumor necrosis factor receptor superfamily binding
W	0005164	molecular_function	tumor necrosis factor receptor binding
W	0006955	biological_process	immune response
W	0016020	cellular_component	membrane
W	0032813	molecular_function	tumor necrosis factor receptor superfamily binding

Functional Information from PROSITE/UniProt

site_id	PS00197
Number of Residues	9
Details	2FE2S_FER_1 2Fe-2S ferredoxin-type iron-sulfur binding region signature. CLGAGCSMC

Chain	Residue	Details
B	CYS94-CYS102

---

site_id	PS00251
Number of Residues	17
Details	THD_1 Tumor necrosis factor (TNF) homology domain (THD) signature. LvVAkAGVYYVffQLeL

Chain	Residue	Details
A	LEU133-LEU149

---

site_id	PS00652
Number of Residues	41
Details	TNFR_NGFR_1 TNFR/NGFR family cysteine-rich region signature. Cppns..Fssaggqrt..CdiCrq.Ckgvfrtrke..CsstsnaECDC

Chain	Residue	Details
B	CYS48-CYS88

---

site_id	PS01186
Number of Residues	14
Details	EGF_2 EGF-like domain signature 2. CdCtpGFhclgag..C

Chain	Residue	Details
B	CYS86-CYS99

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	351
Details	Repeat: {"description":"TNFR-Cys 2"}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	341
Details	Repeat: {"description":"TNFR-Cys 3"}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	360
Details	Repeat: {"description":"TNFR-Cys 4"}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	24
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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