6A34
Crystal structure of 5-methylthioribose 1-phosphate isomerase from Pyrococcus horikoshii OT3 - Form I
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0009086 | biological_process | methionine biosynthetic process |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0019284 | biological_process | L-methionine salvage from S-adenosylmethionine |
| A | 0044237 | biological_process | cellular metabolic process |
| A | 0044249 | biological_process | cellular biosynthetic process |
| A | 0046523 | molecular_function | S-methyl-5-thioribose-1-phosphate isomerase activity |
| B | 0009086 | biological_process | methionine biosynthetic process |
| B | 0016853 | molecular_function | isomerase activity |
| B | 0019284 | biological_process | L-methionine salvage from S-adenosylmethionine |
| B | 0044237 | biological_process | cellular metabolic process |
| B | 0044249 | biological_process | cellular biosynthetic process |
| B | 0046523 | molecular_function | S-methyl-5-thioribose-1-phosphate isomerase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue HEZ A 401 |
| Chain | Residue |
| A | THR332 |
| A | TRP342 |
| A | TRP342 |
| A | HOH560 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | binding site for residue HEZ B 401 |
| Chain | Residue |
| A | ASN162 |
| B | TYR319 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue HEZ B 402 |
| Chain | Residue |
| B | PHE238 |
| A | TYR319 |
| B | ASN162 |
| B | LYS194 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue HEZ B 403 |
| Chain | Residue |
| B | VAL157 |
| B | THR332 |
| B | TRP342 |
| B | PRO343 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton donor => ECO:0000255|HAMAP-Rule:MF_01678 |
| Chain | Residue | Details |
| A | ASP247 | |
| B | ASP247 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_01678 |
| Chain | Residue | Details |
| A | ARG57 | |
| A | ARG100 | |
| A | GLN206 | |
| A | ASN257 | |
| B | ARG57 | |
| B | ARG100 | |
| B | GLN206 | |
| B | ASN257 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | SITE: Transition state stabilizer => ECO:0000255|HAMAP-Rule:MF_01678 |
| Chain | Residue | Details |
| A | CYS167 | |
| B | CYS167 |
