6A34
Crystal structure of 5-methylthioribose 1-phosphate isomerase from Pyrococcus horikoshii OT3 - Form I
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0009086 | biological_process | methionine biosynthetic process |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0019509 | biological_process | L-methionine salvage from methylthioadenosine |
| A | 0046523 | molecular_function | S-methyl-5-thioribose-1-phosphate isomerase activity |
| B | 0008652 | biological_process | amino acid biosynthetic process |
| B | 0009086 | biological_process | methionine biosynthetic process |
| B | 0016853 | molecular_function | isomerase activity |
| B | 0019509 | biological_process | L-methionine salvage from methylthioadenosine |
| B | 0046523 | molecular_function | S-methyl-5-thioribose-1-phosphate isomerase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue HEZ A 401 |
| Chain | Residue |
| A | THR332 |
| A | TRP342 |
| A | TRP342 |
| A | HOH560 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | binding site for residue HEZ B 401 |
| Chain | Residue |
| A | ASN162 |
| B | TYR319 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue HEZ B 402 |
| Chain | Residue |
| B | PHE238 |
| A | TYR319 |
| B | ASN162 |
| B | LYS194 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue HEZ B 403 |
| Chain | Residue |
| B | VAL157 |
| B | THR332 |
| B | TRP342 |
| B | PRO343 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"HAMAP-Rule","id":"MF_01678","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01678","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Site: {"description":"Transition state stabilizer","evidences":[{"source":"HAMAP-Rule","id":"MF_01678","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
