5ZZ5

Redox-sensing transcriptional repressor Rex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0003700	molecular_function	DNA-binding transcription factor activity
A	0005737	cellular_component	cytoplasm
A	0006355	biological_process	regulation of DNA-templated transcription
A	0045892	biological_process	negative regulation of DNA-templated transcription
A	0051775	biological_process	response to redox state
B	0003677	molecular_function	DNA binding
B	0003700	molecular_function	DNA-binding transcription factor activity
B	0005737	cellular_component	cytoplasm
B	0006355	biological_process	regulation of DNA-templated transcription
B	0045892	biological_process	negative regulation of DNA-templated transcription
B	0051775	biological_process	response to redox state
C	0003677	molecular_function	DNA binding
C	0003700	molecular_function	DNA-binding transcription factor activity
C	0005737	cellular_component	cytoplasm
C	0006355	biological_process	regulation of DNA-templated transcription
C	0045892	biological_process	negative regulation of DNA-templated transcription
C	0051775	biological_process	response to redox state
D	0003677	molecular_function	DNA binding
D	0003700	molecular_function	DNA-binding transcription factor activity
D	0005737	cellular_component	cytoplasm
D	0006355	biological_process	regulation of DNA-templated transcription
D	0045892	biological_process	negative regulation of DNA-templated transcription
D	0051775	biological_process	response to redox state

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue GOL A 301

Chain	Residue
A	ALA152
A	VAL153
A	PHE176
A	ALA177
A	HOH429
B	TYR100

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site_id	AC2
Number of Residues	1
Details	binding site for residue GOL B 301

Chain	Residue
B	ILE192

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site_id	AC3
Number of Residues	6
Details	binding site for residue GOL C 301

Chain	Residue
C	PRO154
C	PHE176
C	PRO178
D	TYR100
C	ALA152
C	VAL153

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site_id	AC4
Number of Residues	6
Details	binding site for residue GOL D 301

Chain	Residue
C	TYR100
D	ILE93
D	ALA152
D	VAL153
D	PRO154
D	PHE176

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	156
Details	DNA_BIND: H-T-H motif => ECO:0000255|HAMAP-Rule:MF_01131

Chain	Residue	Details
A	SER15-PHE54
B	SER15-PHE54
C	SER15-PHE54
D	SER15-PHE54

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site_id	SWS_FT_FI2
Number of Residues	4
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_01131

Chain	Residue	Details
A	GLY89
B	GLY89
C	GLY89
D	GLY89

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