Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

5ZWH

Covalent bond formation between histidine of Vitamin D receptor (VDR) and a full agonist having an ene-ynone group via conjugate addition reaction

Functional Information from GO Data
ChainGOidnamespacecontents
A0003677molecular_functionDNA binding
A0004879molecular_functionnuclear receptor activity
A0006355biological_processregulation of DNA-templated transcription
Functional Information from PDB Data
site_idAC1
Number of Residues14
Detailsbinding site for residue 9KX A 501
ChainResidue
ATYR143
AHIS301
AHIS393
ATYR397
A9N9502
AHOH604
AVAL230
ASER233
AILE264
AARG270
ASER271
ASER274
ATRP282
AVAL296

site_idAC2
Number of Residues13
Detailsbinding site for residue 9N9 A 502
ChainResidue
ATYR143
ALEU223
AALA227
AVAL230
ASER233
AMET268
AARG270
ASER271
ASER274
ATRP282
AHIS301
ALEU305
A9KX501

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues6
DetailsBINDING: BINDING => ECO:0000269|PubMed:15065852, ECO:0007744|PDB:1RK3
ChainResidueDetails
ATYR143
AMET280
ALYS317
ALEU321
AVAL348

222926

PDB entries from 2024-07-24

PDB statisticsPDBj update infoContact PDBjnumon