5ZUW

Crystal structure of H99Q mutant of phosphomannose isomerase from Salmonella typhimurium

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004476	molecular_function	mannose-6-phosphate isomerase activity
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0005975	biological_process	carbohydrate metabolic process
A	0008270	molecular_function	zinc ion binding
A	0009298	biological_process	GDP-mannose biosynthetic process
A	0016853	molecular_function	isomerase activity
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	binding site for residue EDO A 401

Chain	Residue
A	LEU94
A	SER95
A	GLN97
A	HIS255
A	ALA256
A	TYR257
A	HOH521

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site_id	AC2
Number of Residues	7
Details	binding site for residue EDO A 402

Chain	Residue
A	ASN237
A	VAL238
A	ALA298
A	HOH528
A	HOH557
A	ARG149
A	ASP153

---

site_id	AC3
Number of Residues	6
Details	binding site for residue EDO A 403

Chain	Residue
A	PHE137
A	ALA138
A	PRO243
A	GLY244
A	GLU347
A	ARG383

---

site_id	AC4
Number of Residues	3
Details	binding site for residue EDO A 404

Chain	Residue
A	TYR11
A	TRP13
A	HOH510

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Functional Information from PROSITE/UniProt

site_id	PS00965
Number of Residues	9
Details	PMI_I_1 Phosphomannose isomerase type I signature 1. YkDpNHKPE

Chain	Residue	Details
A	TYR126-GLU134

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site_id	PS00966
Number of Residues	26
Details	PMI_I_2 Phosphomannose isomerase type I signature 2. HAYLqGvaLEvMAnSDNvLRAGlTPK

Chain	Residue	Details
A	HIS255-LYS280

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Active site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	4
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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