5ZTB

Structure of Sulfurtransferase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000049	molecular_function	tRNA binding
A	0002098	biological_process	tRNA wobble uridine modification
A	0002143	biological_process	tRNA wobble position uridine thiolation
A	0002144	cellular_component	cytosolic tRNA wobble base thiouridylase complex
A	0008033	biological_process	tRNA processing
A	0034227	biological_process	tRNA thio-modification
B	0000049	molecular_function	tRNA binding
B	0002098	biological_process	tRNA wobble uridine modification
B	0002143	biological_process	tRNA wobble position uridine thiolation
B	0002144	cellular_component	cytosolic tRNA wobble base thiouridylase complex
B	0008033	biological_process	tRNA processing
B	0034227	biological_process	tRNA thio-modification
C	0000049	molecular_function	tRNA binding
C	0002098	biological_process	tRNA wobble uridine modification
C	0002143	biological_process	tRNA wobble position uridine thiolation
C	0002144	cellular_component	cytosolic tRNA wobble base thiouridylase complex
C	0008033	biological_process	tRNA processing
C	0034227	biological_process	tRNA thio-modification

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	binding site for residue GOL E 101

Chain	Residue
B	ARG204
B	HOH547
E	PRO32
E	VAL35
E	VAL36
E	ALA37
E	LEU44
E	HOH201

---

site_id	AC2
Number of Residues	5
Details	binding site for residue SF4 B 401

Chain	Residue
B	CYS133
B	CYS222
B	ASN224
E	GLY65
B	CYS130

---

site_id	AC3
Number of Residues	4
Details	binding site for residue ZN B 402

Chain	Residue
B	CYS3
B	CYS6
B	CYS22
B	HIS25

---

site_id	AC4
Number of Residues	4
Details	binding site for residue ZN B 403

Chain	Residue
B	CYS274
B	CYS277
B	CYS286
B	CYS289

---

site_id	AC5
Number of Residues	17
Details	binding site for residue ATP B 404

Chain	Residue
B	ALA53
B	VAL54
B	SER55
B	GLY57
B	LYS58
B	ASP59
B	SER60
B	LEU77
B	ILE79
B	LYS137
B	THR155
B	GLY156
B	HIS157
B	HOH503
B	HOH505
E	SER63
E	GLY65

---

site_id	AC6
Number of Residues	1
Details	binding site for residue SO4 B 405

Chain	Residue
B	HOH510

---

site_id	AC7
Number of Residues	2
Details	binding site for residue SO4 B 406

Chain	Residue
B	ARG298
B	LYS301

---

site_id	AC8
Number of Residues	5
Details	binding site for residue SO4 B 407

Chain	Residue
B	THR281
B	THR282
B	CYS286
B	ALA287
B	ARG290

---

site_id	AC9
Number of Residues	3
Details	binding site for residue SO4 B 408

Chain	Residue
B	LYS137
B	HIS157
B	HOH504

---

site_id	AD1
Number of Residues	5
Details	binding site for residue SF4 A 401

Chain	Residue
A	CYS130
A	CYS133
A	CYS222
A	ASN224
D	GLY65

---

site_id	AD2
Number of Residues	4
Details	binding site for residue ZN A 402

Chain	Residue
A	CYS3
A	CYS6
A	CYS22
A	HIS25

---

site_id	AD3
Number of Residues	4
Details	binding site for residue ZN A 403

Chain	Residue
A	CYS274
A	CYS277
A	CYS286
A	CYS289

---

site_id	AD4
Number of Residues	14
Details	binding site for residue ATP A 404

Chain	Residue
A	ALA53
A	VAL54
A	SER55
A	GLY57
A	LYS58
A	ASP59
A	SER60
A	LEU77
A	ILE79
A	LYS137
A	THR155
A	GLY156
A	HIS157
D	GLY65

---

site_id	AD5
Number of Residues	4
Details	binding site for residue SO4 A 405

Chain	Residue
A	THR281
A	THR282
A	ALA287
A	ARG290

---

site_id	AD6
Number of Residues	5
Details	binding site for residue SF4 C 401

Chain	Residue
C	CYS130
C	CYS133
C	CYS222
C	ASN224
F	GLY65

---

site_id	AD7
Number of Residues	4
Details	binding site for residue ZN C 402

Chain	Residue
C	CYS3
C	CYS6
C	CYS22
C	HIS25

---

site_id	AD8
Number of Residues	4
Details	binding site for residue ZN C 403

Chain	Residue
C	CYS274
C	CYS277
C	CYS286
C	CYS289

---

site_id	AD9
Number of Residues	15
Details	binding site for residue ATP C 404

Chain	Residue
C	SER60
C	LEU77
C	ILE79
C	LYS137
C	THR155
C	GLY156
C	HIS157
F	SER63
F	GLY65
C	ALA53
C	VAL54
C	SER55
C	GLY57
C	LYS58
C	ASP59

---

site_id	AE1
Number of Residues	5
Details	binding site for residue SO4 C 405

Chain	Residue
C	THR281
C	THR282
C	CYS286
C	ALA287
C	ARG290

---

site_id	AE2
Number of Residues	2
Details	binding site for residue SO4 C 406

Chain	Residue
C	ARG36
C	ARG40

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	Modified residue: {"description":"Glycyl adenylate; alternate","evidences":[{"source":"PubMed","id":"19037260","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	6
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Gly-Lys) (interchain with K-? in acceptor proteins); alternate","evidences":[{"source":"PubMed","id":"22467871","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	24
Details	Binding site: {"evidences":[{"source":"PubMed","id":"28439027","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5B4E","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5B4F","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5GHA","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	18
Details	Binding site: {"evidences":[{"source":"PubMed","id":"28439027","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5B4E","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	9
Details	Binding site: {"evidences":[{"source":"PubMed","id":"28439027","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5B4E","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5B4F","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	12
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in TtuB)","evidences":[{"source":"PubMed","id":"22467871","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---