5ZPI

Copper amine oxidase from Arthrobacter globiformis anaerobically reduced by ethylamine at pH 6 at 293 K (3)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005507	molecular_function	copper ion binding
A	0008131	molecular_function	primary methylamine oxidase activity
A	0009308	biological_process	amine metabolic process
A	0016491	molecular_function	oxidoreductase activity
A	0016641	molecular_function	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor
A	0046872	molecular_function	metal ion binding
A	0048038	molecular_function	quinone binding
B	0005507	molecular_function	copper ion binding
B	0008131	molecular_function	primary methylamine oxidase activity
B	0009308	biological_process	amine metabolic process
B	0016491	molecular_function	oxidoreductase activity
B	0016641	molecular_function	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor
B	0046872	molecular_function	metal ion binding
B	0048038	molecular_function	quinone binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue CU A 1001

Chain	Residue
A	TYQ382
A	HIS431
A	HIS433
A	HIS592
A	HOH1164
A	HOH1378

---

site_id	AC2
Number of Residues	5
Details	binding site for residue NA A 1002

Chain	Residue
A	ILE582
A	HOH1227
A	ASP440
A	MET441
A	ASP581

---

site_id	AC3
Number of Residues	5
Details	binding site for residue EDO A 1003

Chain	Residue
A	GLU347
A	ARG370
A	LYS401
A	HOH1201
B	TRP349

---

site_id	AC4
Number of Residues	8
Details	binding site for residue EDO A 1004

Chain	Residue
A	ASP488
A	ALA489
A	ARG490
A	HOH1423
B	ASP488
B	ALA489
B	ARG490
B	HOH1141

---

site_id	AC5
Number of Residues	6
Details	binding site for residue EDO A 1005

Chain	Residue
A	PRO228
A	PHE230
A	THR231
A	HOH1108
A	HOH1138
B	LYS218

---

site_id	AC6
Number of Residues	6
Details	binding site for residue CU B 701

Chain	Residue
B	TYQ382
B	HIS431
B	HIS433
B	HIS592
B	HOH831
B	HOH909

---

site_id	AC7
Number of Residues	5
Details	binding site for residue NA B 702

Chain	Residue
B	ASP440
B	MET441
B	ASP581
B	ILE582
B	HOH1037

---

site_id	AC8
Number of Residues	4
Details	binding site for residue EDO B 703

Chain	Residue
A	HIS515
A	LYS610
B	ASP605
B	HOH807

---

site_id	AC9
Number of Residues	6
Details	binding site for residue EDO B 704

Chain	Residue
A	TRP349
B	GLU347
B	ARG370
B	LYS401
B	HOH852
B	HOH1009

---

site_id	AD1
Number of Residues	4
Details	binding site for residue EDO B 705

Chain	Residue
B	HIS515
B	HIS517
B	LYS610
B	HOH992

---

site_id	AD2
Number of Residues	9
Details	binding site for residue EDO B 706

Chain	Residue
B	ALA15
B	LEU42
B	GLY43
B	PHE249
B	ASP250
B	VAL251
B	VAL327
B	HOH931
B	HOH959

---

Functional Information from PROSITE/UniProt

site_id	PS01164
Number of Residues	14
Details	COPPER_AMINE_OXID_1 Copper amine oxidase topaquinone signature. MVIsfftTigNYDY

Chain	Residue	Details
A	MET371-TYR384

---

site_id	PS01165
Number of Residues	14
Details	COPPER_AMINE_OXID_2 Copper amine oxidase copper-binding site signature. TfGltHFprvEDwP

Chain	Residue	Details
A	THR587-PRO600

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"UniProtKB","id":"P12807","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	Active site: {"description":"Schiff-base intermediate with substrate; via topaquinone","evidences":[{"source":"UniProtKB","id":"P12807","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	22
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P12807","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"PubMed","id":"9405045","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1AV4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1AVL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1IU7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1IVU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1IVV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1IVW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1IVX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1RJO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1SIH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1SII","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1UI8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1W4N","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1W5Z","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1W6C","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1W6G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2BT3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2CFD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2CFG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2CFK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2CFL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2CFW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2CG0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2CG1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2CWT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2CWU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2CWV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2D1W","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2E2T","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2E2U","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2E2V","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2YX9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZL8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3AMO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3KII","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3KN4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3WA2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3WA3","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	2
Details	Modified residue: {"description":"2',4',5'-topaquinone","evidences":[{"source":"PubMed","id":"9405045","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---