5ZLT

Crystal structure of UDP-GlcNAc 2-epimerase NeuC complexed with UDP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0003824	molecular_function	catalytic activity
A	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
A	0006047	biological_process	UDP-N-acetylglucosamine metabolic process
A	0008761	molecular_function	UDP-N-acetylglucosamine 2-epimerase activity
A	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
A	0102388	molecular_function	UDP-N,N'-diacetylbacillosamine 2-epimerase activity
B	0000166	molecular_function	nucleotide binding
B	0003824	molecular_function	catalytic activity
B	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
B	0006047	biological_process	UDP-N-acetylglucosamine metabolic process
B	0008761	molecular_function	UDP-N-acetylglucosamine 2-epimerase activity
B	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
B	0102388	molecular_function	UDP-N,N'-diacetylbacillosamine 2-epimerase activity
C	0000166	molecular_function	nucleotide binding
C	0003824	molecular_function	catalytic activity
C	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
C	0006047	biological_process	UDP-N-acetylglucosamine metabolic process
C	0008761	molecular_function	UDP-N-acetylglucosamine 2-epimerase activity
C	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
C	0102388	molecular_function	UDP-N,N'-diacetylbacillosamine 2-epimerase activity
D	0000166	molecular_function	nucleotide binding
D	0003824	molecular_function	catalytic activity
D	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
D	0006047	biological_process	UDP-N-acetylglucosamine metabolic process
D	0008761	molecular_function	UDP-N-acetylglucosamine 2-epimerase activity
D	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
D	0102388	molecular_function	UDP-N,N'-diacetylbacillosamine 2-epimerase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue SO4 A 400

Chain	Residue
A	HIS210
A	SER289
A	SER290
A	ARG309

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site_id	AC2
Number of Residues	11
Details	binding site for residue UDP B 400

Chain	Residue
B	LYS268
B	ILE272
B	TYR275
B	SER289
B	SER290
B	ARG309
B	ARG11
B	ALA12
B	HIS210
B	SER238
B	TYR239

---

site_id	AC3
Number of Residues	4
Details	binding site for residue SO4 C 400

Chain	Residue
C	SER289
C	SER290
C	ARG309
C	GLN310

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site_id	AC4
Number of Residues	12
Details	binding site for residue UDP D 400

Chain	Residue
D	ALA12
D	HIS210
D	SER238
D	LYS268
D	SER269
D	PHE270
D	ILE272
D	TYR275
D	SER289
D	SER290
D	ARG309
D	HOH529

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