5ZL6
Histidine Racemase from Leuconostoc mesenteroides subsp. sake NBRC 102480
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0006522 | biological_process | alanine metabolic process |
| A | 0008784 | molecular_function | alanine racemase activity |
| A | 0009252 | biological_process | peptidoglycan biosynthetic process |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0030170 | molecular_function | pyridoxal phosphate binding |
| A | 0030632 | biological_process | D-alanine biosynthetic process |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0006522 | biological_process | alanine metabolic process |
| B | 0008784 | molecular_function | alanine racemase activity |
| B | 0009252 | biological_process | peptidoglycan biosynthetic process |
| B | 0016853 | molecular_function | isomerase activity |
| B | 0030170 | molecular_function | pyridoxal phosphate binding |
| B | 0030632 | biological_process | D-alanine biosynthetic process |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0005829 | cellular_component | cytosol |
| C | 0006522 | biological_process | alanine metabolic process |
| C | 0008784 | molecular_function | alanine racemase activity |
| C | 0009252 | biological_process | peptidoglycan biosynthetic process |
| C | 0016853 | molecular_function | isomerase activity |
| C | 0030170 | molecular_function | pyridoxal phosphate binding |
| C | 0030632 | biological_process | D-alanine biosynthetic process |
| D | 0003824 | molecular_function | catalytic activity |
| D | 0005829 | cellular_component | cytosol |
| D | 0006522 | biological_process | alanine metabolic process |
| D | 0008784 | molecular_function | alanine racemase activity |
| D | 0009252 | biological_process | peptidoglycan biosynthetic process |
| D | 0016853 | molecular_function | isomerase activity |
| D | 0030170 | molecular_function | pyridoxal phosphate binding |
| D | 0030632 | biological_process | D-alanine biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | binding site for residue PLP A 401 |
| Chain | Residue |
| A | LYS40 |
| A | GLY224 |
| A | ILE225 |
| A | HOH589 |
| A | HOH645 |
| A | HOH696 |
| A | PHE44 |
| A | LEU86 |
| A | ARG138 |
| A | TRP166 |
| A | HIS168 |
| A | ASN205 |
| A | THR206 |
| A | ARG222 |
| site_id | AC2 |
| Number of Residues | 22 |
| Details | binding site for Di-peptide PLP B 401 and LYS B 40 |
| Chain | Residue |
| A | ASP316 |
| B | VAL38 |
| B | LEU39 |
| B | ALA41 |
| B | ASN42 |
| B | ALA43 |
| B | PHE44 |
| B | MET65 |
| B | ALA66 |
| B | GLU70 |
| B | ARG138 |
| B | TRP166 |
| B | HIS168 |
| B | THR206 |
| B | ARG222 |
| B | GLY224 |
| B | ILE225 |
| B | HOH516 |
| B | HOH528 |
| B | HOH546 |
| B | HOH685 |
| B | HOH686 |
| site_id | AC3 |
| Number of Residues | 17 |
| Details | binding site for Di-peptide PLP B 402 and LYS B 261 |
| Chain | Residue |
| B | LYS260 |
| B | GLY262 |
| B | ASP263 |
| B | HIS272 |
| B | ALA273 |
| B | PRO274 |
| B | ASP276 |
| B | HOH503 |
| B | HOH507 |
| B | HOH630 |
| B | HOH646 |
| B | HOH673 |
| B | HOH989 |
| C | GLY296 |
| C | ARG298 |
| C | HIS308 |
| C | HOH510 |
| site_id | AC4 |
| Number of Residues | 22 |
| Details | binding site for Di-peptide PLP C 401 and LYS C 40 |
| Chain | Residue |
| C | VAL38 |
| C | LEU39 |
| C | ALA41 |
| C | ASN42 |
| C | ALA43 |
| C | PHE44 |
| C | MET65 |
| C | ALA66 |
| C | ARG138 |
| C | TRP166 |
| C | HIS168 |
| C | ASN205 |
| C | THR206 |
| C | ARG222 |
| C | GLY224 |
| C | ILE225 |
| C | HOH535 |
| C | HOH550 |
| C | HOH588 |
| C | HOH622 |
| C | HOH690 |
| D | ASP316 |
| site_id | AC5 |
| Number of Residues | 24 |
| Details | binding site for Di-peptide PLP D 401 and LYS D 40 |
| Chain | Residue |
| C | MET315 |
| C | ASP316 |
| D | VAL38 |
| D | LEU39 |
| D | ALA41 |
| D | ASN42 |
| D | ALA43 |
| D | PHE44 |
| D | MET65 |
| D | ALA66 |
| D | GLU70 |
| D | ARG138 |
| D | TRP166 |
| D | HIS168 |
| D | ASN205 |
| D | THR206 |
| D | ARG222 |
| D | GLY224 |
| D | ILE225 |
| D | HOH503 |
| D | HOH580 |
| D | HOH586 |
| D | HOH593 |
| D | HOH750 |
| site_id | AC6 |
| Number of Residues | 18 |
| Details | binding site for Di-peptide PLP D 402 and LYS D 261 |
| Chain | Residue |
| A | GLY296 |
| A | ARG298 |
| A | HIS308 |
| A | HOH558 |
| D | LYS260 |
| D | GLY262 |
| D | ASP263 |
| D | HIS272 |
| D | ALA273 |
| D | PRO274 |
| D | ASP276 |
| D | HOH520 |
| D | HOH541 |
| D | HOH651 |
| D | HOH684 |
| D | HOH713 |
| D | HOH739 |
| D | HOH758 |
