5ZJK
Structure of myroilysin
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004222 | molecular_function | metalloendopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0008237 | molecular_function | metallopeptidase activity |
| A | 0008270 | molecular_function | zinc ion binding |
| B | 0004222 | molecular_function | metalloendopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
| B | 0008237 | molecular_function | metallopeptidase activity |
| B | 0008270 | molecular_function | zinc ion binding |
| C | 0004222 | molecular_function | metalloendopeptidase activity |
| C | 0006508 | biological_process | proteolysis |
| C | 0008237 | molecular_function | metallopeptidase activity |
| C | 0008270 | molecular_function | zinc ion binding |
| D | 0004222 | molecular_function | metalloendopeptidase activity |
| D | 0006508 | biological_process | proteolysis |
| D | 0008237 | molecular_function | metallopeptidase activity |
| D | 0008270 | molecular_function | zinc ion binding |
| E | 0004222 | molecular_function | metalloendopeptidase activity |
| E | 0006508 | biological_process | proteolysis |
| E | 0008237 | molecular_function | metallopeptidase activity |
| E | 0008270 | molecular_function | zinc ion binding |
| F | 0004222 | molecular_function | metalloendopeptidase activity |
| F | 0006508 | biological_process | proteolysis |
| F | 0008237 | molecular_function | metallopeptidase activity |
| F | 0008270 | molecular_function | zinc ion binding |
| G | 0004222 | molecular_function | metalloendopeptidase activity |
| G | 0006508 | biological_process | proteolysis |
| G | 0008237 | molecular_function | metallopeptidase activity |
| G | 0008270 | molecular_function | zinc ion binding |
| H | 0004222 | molecular_function | metalloendopeptidase activity |
| H | 0006508 | biological_process | proteolysis |
| H | 0008237 | molecular_function | metallopeptidase activity |
| H | 0008270 | molecular_function | zinc ion binding |
| I | 0004222 | molecular_function | metalloendopeptidase activity |
| I | 0006508 | biological_process | proteolysis |
| I | 0008237 | molecular_function | metallopeptidase activity |
| I | 0008270 | molecular_function | zinc ion binding |
| J | 0004222 | molecular_function | metalloendopeptidase activity |
| J | 0006508 | biological_process | proteolysis |
| J | 0008237 | molecular_function | metallopeptidase activity |
| J | 0008270 | molecular_function | zinc ion binding |
| K | 0004222 | molecular_function | metalloendopeptidase activity |
| K | 0006508 | biological_process | proteolysis |
| K | 0008237 | molecular_function | metallopeptidase activity |
| K | 0008270 | molecular_function | zinc ion binding |
| L | 0004222 | molecular_function | metalloendopeptidase activity |
| L | 0006508 | biological_process | proteolysis |
| L | 0008237 | molecular_function | metallopeptidase activity |
| L | 0008270 | molecular_function | zinc ion binding |
| M | 0004222 | molecular_function | metalloendopeptidase activity |
| M | 0006508 | biological_process | proteolysis |
| M | 0008237 | molecular_function | metallopeptidase activity |
| M | 0008270 | molecular_function | zinc ion binding |
| N | 0004222 | molecular_function | metalloendopeptidase activity |
| N | 0006508 | biological_process | proteolysis |
| N | 0008237 | molecular_function | metallopeptidase activity |
| N | 0008270 | molecular_function | zinc ion binding |
| O | 0004222 | molecular_function | metalloendopeptidase activity |
| O | 0006508 | biological_process | proteolysis |
| O | 0008237 | molecular_function | metallopeptidase activity |
| O | 0008270 | molecular_function | zinc ion binding |
| P | 0004222 | molecular_function | metalloendopeptidase activity |
| P | 0006508 | biological_process | proteolysis |
| P | 0008237 | molecular_function | metallopeptidase activity |
| P | 0008270 | molecular_function | zinc ion binding |
| Q | 0004222 | molecular_function | metalloendopeptidase activity |
| Q | 0006508 | biological_process | proteolysis |
| Q | 0008237 | molecular_function | metallopeptidase activity |
| Q | 0008270 | molecular_function | zinc ion binding |
| R | 0004222 | molecular_function | metalloendopeptidase activity |
| R | 0006508 | biological_process | proteolysis |
| R | 0008237 | molecular_function | metallopeptidase activity |
| R | 0008270 | molecular_function | zinc ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | binding site for residue ZN A 301 |
| Chain | Residue |
| A | HIS140 |
| A | HIS144 |
| A | HIS150 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue PO4 B 301 |
| Chain | Residue |
| B | TYR57 |
| B | GLY88 |
| B | THR89 |
| B | ARG93 |
| B | SER115 |
| I | LYS179 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue ZN B 302 |
| Chain | Residue |
| B | HIS140 |
| B | HIS144 |
| B | HIS150 |
| B | TYR208 |
| B | HOH440 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue ZN C 301 |
| Chain | Residue |
| C | HIS140 |
| C | HIS144 |
| C | HIS150 |
| C | TYR208 |
| C | HOH456 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue PO4 D 301 |
| Chain | Residue |
| D | TYR57 |
| D | GLY88 |
| D | THR89 |
| D | SER115 |
| D | HOH418 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue ZN D 302 |
| Chain | Residue |
| D | HIS140 |
| D | HIS144 |
| D | HIS150 |
| D | TYR208 |
| D | HOH426 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue PO4 E 301 |
| Chain | Residue |
| E | TYR57 |
| E | GLY88 |
| E | THR89 |
| E | ARG93 |
| E | SER115 |
| P | LYS179 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue ZN E 302 |
| Chain | Residue |
| E | HIS140 |
| E | HIS144 |
| E | HIS150 |
| E | TYR208 |
| E | HOH432 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue PO4 F 301 |
| Chain | Residue |
| A | LYS179 |
| F | TYR57 |
| F | GLY88 |
| F | THR89 |
| F | ARG93 |
| F | SER115 |
| site_id | AD1 |
| Number of Residues | 4 |
| Details | binding site for residue ZN F 302 |
| Chain | Residue |
| F | HIS140 |
| F | HIS144 |
| F | HIS150 |
| F | TYR208 |
| site_id | AD2 |
| Number of Residues | 7 |
| Details | binding site for residue PO4 G 301 |
| Chain | Residue |
| G | TYR57 |
| G | GLY88 |
| G | THR89 |
| G | ARG93 |
| G | SER115 |
| G | HOH414 |
| Q | LYS179 |
| site_id | AD3 |
| Number of Residues | 4 |
| Details | binding site for residue ZN G 302 |
| Chain | Residue |
| G | HIS140 |
| G | HIS144 |
| G | HIS150 |
| G | TYR208 |
| site_id | AD4 |
| Number of Residues | 5 |
| Details | binding site for residue PO4 H 301 |
| Chain | Residue |
| H | TYR57 |
| H | GLY88 |
| H | ARG93 |
| H | SER115 |
| N | LYS179 |
| site_id | AD5 |
| Number of Residues | 5 |
| Details | binding site for residue ZN H 302 |
| Chain | Residue |
| H | HIS140 |
| H | GLU141 |
| H | HIS144 |
| H | HIS150 |
| H | TYR208 |
| site_id | AD6 |
| Number of Residues | 4 |
| Details | binding site for residue PO4 I 301 |
| Chain | Residue |
| I | TYR57 |
| I | GLY88 |
| I | ARG93 |
| I | SER115 |
| site_id | AD7 |
| Number of Residues | 5 |
| Details | binding site for residue ZN I 302 |
| Chain | Residue |
| I | HIS140 |
| I | HIS144 |
| I | HIS150 |
| I | TYR208 |
| I | HOH412 |
| site_id | AD8 |
| Number of Residues | 7 |
| Details | binding site for residue PO4 J 301 |
| Chain | Residue |
| F | LYS179 |
| J | TYR57 |
| J | GLY88 |
| J | THR89 |
| J | ARG93 |
| J | SER115 |
| J | HOH421 |
| site_id | AD9 |
| Number of Residues | 5 |
| Details | binding site for residue ZN J 302 |
| Chain | Residue |
| J | HIS140 |
| J | HIS144 |
| J | HIS150 |
| J | TYR208 |
| J | HOH431 |
| site_id | AE1 |
| Number of Residues | 6 |
| Details | binding site for residue PO4 K 301 |
| Chain | Residue |
| K | TYR57 |
| K | GLY88 |
| K | THR89 |
| K | SER115 |
| M | LYS179 |
| M | HOH401 |
| site_id | AE2 |
| Number of Residues | 5 |
| Details | binding site for residue ZN K 302 |
| Chain | Residue |
| K | HIS144 |
| K | HIS150 |
| K | TYR208 |
| K | HOH405 |
| K | HIS140 |
| site_id | AE3 |
| Number of Residues | 5 |
| Details | binding site for residue ZN L 301 |
| Chain | Residue |
| L | HIS140 |
| L | HIS144 |
| L | HIS150 |
| L | TYR208 |
| L | HOH421 |
| site_id | AE4 |
| Number of Residues | 4 |
| Details | binding site for residue PO4 M 301 |
| Chain | Residue |
| M | TYR57 |
| M | GLY88 |
| M | THR89 |
| M | SER115 |
| site_id | AE5 |
| Number of Residues | 5 |
| Details | binding site for residue ZN M 302 |
| Chain | Residue |
| M | HIS140 |
| M | HIS144 |
| M | HIS150 |
| M | TYR208 |
| M | HOH402 |
| site_id | AE6 |
| Number of Residues | 5 |
| Details | binding site for residue ZN N 301 |
| Chain | Residue |
| N | HIS140 |
| N | HIS144 |
| N | HIS150 |
| N | TYR208 |
| N | HOH401 |
| site_id | AE7 |
| Number of Residues | 5 |
| Details | binding site for residue ZN O 301 |
| Chain | Residue |
| O | HIS140 |
| O | HIS144 |
| O | HIS150 |
| O | TYR208 |
| O | HOH405 |
| site_id | AE8 |
| Number of Residues | 5 |
| Details | binding site for residue PO4 P 301 |
| Chain | Residue |
| P | TYR57 |
| P | GLY88 |
| P | THR89 |
| P | ARG93 |
| P | SER115 |
| site_id | AE9 |
| Number of Residues | 4 |
| Details | binding site for residue ZN P 302 |
| Chain | Residue |
| P | HIS140 |
| P | HIS144 |
| P | HIS150 |
| P | TYR208 |
| site_id | AF1 |
| Number of Residues | 4 |
| Details | binding site for residue PO4 Q 301 |
| Chain | Residue |
| Q | TYR57 |
| Q | GLY88 |
| Q | ARG93 |
| Q | SER115 |
| site_id | AF2 |
| Number of Residues | 4 |
| Details | binding site for residue ZN Q 302 |
| Chain | Residue |
| Q | HIS140 |
| Q | HIS144 |
| Q | HIS150 |
| Q | TYR208 |
| site_id | AF3 |
| Number of Residues | 4 |
| Details | binding site for residue ZN R 301 |
| Chain | Residue |
| R | HIS140 |
| R | HIS144 |
| R | HIS150 |
| R | TYR208 |
Functional Information from PROSITE/UniProt
| site_id | PS00142 |
| Number of Residues | 10 |
| Details | ZINC_PROTEASE Neutral zinc metallopeptidases, zinc-binding region signature. TVIHEFGHAL |
| Chain | Residue | Details |
| A | THR137-LEU146 |
