5ZIO

Crystal structure of NDM-1 in complex with L-captopril

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008270	molecular_function	zinc ion binding
A	0008800	molecular_function	beta-lactamase activity
A	0016787	molecular_function	hydrolase activity
A	0017001	biological_process	antibiotic catabolic process
A	0042597	cellular_component	periplasmic space
A	0046677	biological_process	response to antibiotic
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue ZN A 301

Chain	Residue
A	HIS93
A	HIS95
A	HIS162
A	X8Z303

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site_id	AC2
Number of Residues	4
Details	binding site for residue ZN A 302

Chain	Residue
A	ASP97
A	CYS181
A	HIS223
A	X8Z303

---

site_id	AC3
Number of Residues	10
Details	binding site for residue X8Z A 303

Chain	Residue
A	HIS95
A	ASP97
A	HIS162
A	GLY192
A	ASN193
A	HIS223
A	ZN301
A	ZN302
A	HOH405
A	VAL46

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22713171","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25815530","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22713171","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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