5ZIK
Crystal structure of Ketopantoate reductase from Pseudomonas aeruginosa
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0008677 | molecular_function | 2-dehydropantoate 2-reductase activity |
| A | 0015940 | biological_process | pantothenate biosynthetic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0050661 | molecular_function | NADP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0008677 | molecular_function | 2-dehydropantoate 2-reductase activity |
| B | 0015940 | biological_process | pantothenate biosynthetic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0050661 | molecular_function | NADP binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0008677 | molecular_function | 2-dehydropantoate 2-reductase activity |
| C | 0015940 | biological_process | pantothenate biosynthetic process |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0050661 | molecular_function | NADP binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 401 |
| Chain | Residue |
| A | GLY20 |
| A | ARG21 |
| A | GLY23 |
| A | PRO57 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 402 |
| Chain | Residue |
| A | ASP50 |
| A | PHE139 |
| A | ARG142 |
| A | HOH536 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 403 |
| Chain | Residue |
| C | LEU195 |
| C | ARG290 |
| C | HIS294 |
| A | ARG114 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 401 |
| Chain | Residue |
| B | TYR269 |
| B | HIS273 |
| B | ARG276 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 B 402 |
| Chain | Residue |
| A | ASP50 |
| B | VAL194 |
| B | ASP197 |
| B | VAL255 |
| B | THR256 |
| B | HIS294 |
| B | ARG298 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"UniProtKB","id":"P0A9J4","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 27 |
| Details | Binding site: {"evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"MAR-2018","submissionDatabase":"PDB data bank","title":"Crystal structure of Ketopantoate reductase from Pseudomonas aeruginosa bound to NADP+.","authors":["Khanppnavar B.","Datta S."]}}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 15 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P0A9J4","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
