5ZI3

MDH3 wild type, apo-form

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003729	molecular_function	mRNA binding
A	0003824	molecular_function	catalytic activity
A	0005737	cellular_component	cytoplasm
A	0005739	cellular_component	mitochondrion
A	0005777	cellular_component	peroxisome
A	0005782	cellular_component	peroxisomal matrix
A	0006097	biological_process	glyoxylate cycle
A	0006099	biological_process	tricarboxylic acid cycle
A	0006108	biological_process	malate metabolic process
A	0006635	biological_process	fatty acid beta-oxidation
A	0006735	biological_process	NADH regeneration
A	0016491	molecular_function	oxidoreductase activity
A	0016615	molecular_function	malate dehydrogenase activity
A	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
A	0019752	biological_process	carboxylic acid metabolic process
A	0030060	molecular_function	L-malate dehydrogenase (NAD+) activity
A	0044281	biological_process	small molecule metabolic process
A	0070013	cellular_component	intracellular organelle lumen
B	0003729	molecular_function	mRNA binding
B	0003824	molecular_function	catalytic activity
B	0005737	cellular_component	cytoplasm
B	0005739	cellular_component	mitochondrion
B	0005777	cellular_component	peroxisome
B	0005782	cellular_component	peroxisomal matrix
B	0006097	biological_process	glyoxylate cycle
B	0006099	biological_process	tricarboxylic acid cycle
B	0006108	biological_process	malate metabolic process
B	0006635	biological_process	fatty acid beta-oxidation
B	0006735	biological_process	NADH regeneration
B	0016491	molecular_function	oxidoreductase activity
B	0016615	molecular_function	malate dehydrogenase activity
B	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
B	0019752	biological_process	carboxylic acid metabolic process
B	0030060	molecular_function	L-malate dehydrogenase (NAD+) activity
B	0044281	biological_process	small molecule metabolic process
B	0070013	cellular_component	intracellular organelle lumen

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue GOL B 401

Chain	Residue
B	LYS138
B	PRO139
B	GLY140
B	ASN141
B	SER299
B	VAL300

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site_id	AC2
Number of Residues	7
Details	binding site for residue GOL B 402

Chain	Residue
B	ILE116
B	SER117
B	ASN118
B	MET237
B	VAL13
B	PRO75
B	GLY77

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Functional Information from PROSITE/UniProt

site_id	PS00068
Number of Residues	13
Details	MDH Malate dehydrogenase active site signature. VTNLDlvRAetfL

Chain	Residue	Details
A	VAL145-LEU157

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"UniProtKB","id":"P00346","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	22
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P40926","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU10004","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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