Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 19 |
| Details | binding site for residue HEC A 501 |
| Chain | Residue |
| A | LEU44 |
| A | PHE165 |
| A | LYS191 |
| A | PRO192 |
| A | PRO194 |
| A | HIS195 |
| A | LEU210 |
| A | MET212 |
| A | HEC503 |
| A | HOH681 |
| A | HOH809 |
| A | CYS45 |
| A | CYS48 |
| A | HIS49 |
| A | HIS131 |
| A | ALA161 |
| A | PRO162 |
| A | ILE163 |
| A | GLY164 |
| site_id | AC2 |
| Number of Residues | 21 |
| Details | binding site for residue HEC A 502 |
| Chain | Residue |
| A | ASP69 |
| A | ILE71 |
| A | HIS72 |
| A | PHE75 |
| A | GLU79 |
| A | LEU98 |
| A | CYS99 |
| A | CYS102 |
| A | HIS103 |
| A | TYR148 |
| A | CYS228 |
| A | HIS229 |
| A | ARG232 |
| A | HIS276 |
| A | THR314 |
| A | GLY315 |
| A | ALA316 |
| A | ARG319 |
| A | HEC504 |
| A | HEC505 |
| A | HOH738 |
| site_id | AC3 |
| Number of Residues | 25 |
| Details | binding site for residue HEC A 503 |
| Chain | Residue |
| A | CYS45 |
| A | HIS49 |
| A | ILE52 |
| A | TRP56 |
| A | HIS61 |
| A | VAL125 |
| A | ASN126 |
| A | CYS127 |
| A | CYS130 |
| A | HIS131 |
| A | LEU219 |
| A | ARG220 |
| A | GLN257 |
| A | MET261 |
| A | PHE267 |
| A | ALA268 |
| A | HIS270 |
| A | ARG283 |
| A | HEC501 |
| A | HEC504 |
| A | HOH651 |
| A | HOH669 |
| A | HOH691 |
| A | HOH809 |
| A | HOH837 |
| site_id | AC4 |
| Number of Residues | 19 |
| Details | binding site for residue HEC A 504 |
| Chain | Residue |
| A | MET60 |
| A | HIS61 |
| A | SER64 |
| A | ASP69 |
| A | CYS102 |
| A | ALA224 |
| A | CYS225 |
| A | CYS228 |
| A | HIS229 |
| A | HIS260 |
| A | MET272 |
| A | GLY274 |
| A | GLY275 |
| A | HIS276 |
| A | HIS277 |
| A | HEC502 |
| A | HEC503 |
| A | HOH735 |
| A | HOH738 |
| site_id | AC5 |
| Number of Residues | 19 |
| Details | binding site for residue HEC A 505 |
| Chain | Residue |
| A | TYR404 |
| A | HEC502 |
| A | HOH660 |
| A | HOH738 |
| A | MET226 |
| A | HIS229 |
| A | VAL254 |
| A | CYS256 |
| A | THR258 |
| A | CYS259 |
| A | HIS260 |
| A | GLY274 |
| A | GLY275 |
| A | LEU281 |
| A | SER284 |
| A | PRO309 |
| A | HIS310 |
| A | THR314 |
| A | ARG319 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 506 |
| Chain | Residue |
| A | ARG167 |
| A | ASN193 |
| A | HOH606 |
| A | HOH633 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 507 |
| Chain | Residue |
| A | LEU155 |
| A | ILE435 |
| A | HOH603 |
| A | HOH607 |
