Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

5ZAB

Crystal structure of cf3-aequorin

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005509	molecular_function	calcium ion binding
A	0008218	biological_process	bioluminescence
A	0046872	molecular_function	metal ion binding
B	0005509	molecular_function	calcium ion binding
B	0008218	biological_process	bioluminescence
B	0046872	molecular_function	metal ion binding
C	0005509	molecular_function	calcium ion binding
C	0008218	biological_process	bioluminescence
C	0046872	molecular_function	metal ion binding
D	0005509	molecular_function	calcium ion binding
D	0008218	biological_process	bioluminescence
D	0046872	molecular_function	metal ion binding
E	0005509	molecular_function	calcium ion binding
E	0008218	biological_process	bioluminescence
E	0046872	molecular_function	metal ion binding
F	0005509	molecular_function	calcium ion binding
F	0008218	biological_process	bioluminescence
F	0046872	molecular_function	metal ion binding
G	0005509	molecular_function	calcium ion binding
G	0008218	biological_process	bioluminescence
G	0046872	molecular_function	metal ion binding
H	0005509	molecular_function	calcium ion binding
H	0008218	biological_process	bioluminescence
H	0046872	molecular_function	metal ion binding
I	0005509	molecular_function	calcium ion binding
I	0008218	biological_process	bioluminescence
I	0046872	molecular_function	metal ion binding
J	0005509	molecular_function	calcium ion binding
J	0008218	biological_process	bioluminescence
J	0046872	molecular_function	metal ion binding
K	0005509	molecular_function	calcium ion binding
K	0008218	biological_process	bioluminescence
K	0046872	molecular_function	metal ion binding
L	0005509	molecular_function	calcium ion binding
L	0008218	biological_process	bioluminescence
L	0046872	molecular_function	metal ion binding
M	0005509	molecular_function	calcium ion binding
M	0008218	biological_process	bioluminescence
M	0046872	molecular_function	metal ion binding
N	0005509	molecular_function	calcium ion binding
N	0008218	biological_process	bioluminescence
N	0046872	molecular_function	metal ion binding
O	0005509	molecular_function	calcium ion binding
O	0008218	biological_process	bioluminescence
O	0046872	molecular_function	metal ion binding
P	0005509	molecular_function	calcium ion binding
P	0008218	biological_process	bioluminescence
P	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	15
Details	binding site for residue 9A3 A 201

Chain	Residue
A	HIS16
A	TYR132
A	MET165
A	THR166
A	HIS169
A	TRP173
A	TYR184
A	MET19
A	TYR82
A	TRP86
A	ILE105
A	TRP108
A	GLY109
A	LEU112
A	TRP129

site_id	AC2
Number of Residues	15
Details	binding site for residue 9A3 B 201

Chain	Residue
B	HIS16
B	MET19
B	PHE66
B	TYR82
B	TRP86
B	ILE105
B	TRP108
B	GLY109
B	LEU112
B	TYR132
B	MET165
B	THR166
B	HIS169
B	TRP173
B	TYR184

site_id	AC3
Number of Residues	15
Details	binding site for residue 9A3 C 201

Chain	Residue
C	HIS16
C	MET19
C	TYR82
C	TRP86
C	ILE105
C	TRP108
C	GLY109
C	LEU112
C	TYR132
C	VAL162
C	MET165
C	THR166
C	HIS169
C	TRP173
C	TYR184

site_id	AC4
Number of Residues	15
Details	binding site for residue 9A3 D 201

Chain	Residue
D	HIS16
D	MET19
D	TYR82
D	TRP86
D	ILE105
D	TRP108
D	GLY109
D	LEU112
D	TRP129
D	TYR132
D	MET165
D	THR166
D	HIS169
D	TRP173
D	TYR184

site_id	AC5
Number of Residues	17
Details	binding site for residue 9A3 E 201

Chain	Residue
E	HIS16
E	MET19
E	LYS39
E	PHE66
E	TYR82
E	TRP86
E	ILE105
E	TRP108
E	GLY109
E	LEU112
E	TRP129
E	TYR132
E	MET165
E	THR166
E	HIS169
E	TRP173
E	TYR184

site_id	AC6
Number of Residues	16
Details	binding site for residue 9A3 F 201

Chain	Residue
F	HIS16
F	MET19
F	PHE66
F	TYR82
F	TRP86
F	ILE105
F	TRP108
F	GLY109
F	LEU112
F	TYR132
F	VAL162
F	MET165
F	THR166
F	HIS169
F	TRP173
F	TYR184

site_id	AC7
Number of Residues	16
Details	binding site for residue 9A3 G 201

Chain	Residue
G	GLY109
G	LEU112
G	TRP129
G	TYR132
G	VAL162
G	MET165
G	THR166
G	HIS169
G	TRP173
G	TYR184
G	HIS16
G	MET19
G	TYR82
G	TRP86
G	ILE105
G	TRP108

site_id	AC8
Number of Residues	15
Details	binding site for residue 9A3 H 201

Chain	Residue
H	HIS16
H	MET19
H	PHE66
H	TYR82
H	TRP86
H	ILE105
H	TRP108
H	GLY109
H	TRP129
H	TYR132
H	MET165
H	THR166
H	HIS169
H	TRP173
H	TYR184

site_id	AC9
Number of Residues	16
Details	binding site for residue 9A3 I 201

Chain	Residue
I	HIS16
I	MET19
I	PHE66
I	TYR82
I	TRP86
I	ILE105
I	TRP108
I	GLY109
I	LEU112
I	TRP129
I	TYR132
I	MET165
I	THR166
I	HIS169
I	TRP173
I	TYR184

site_id	AD1
Number of Residues	16
Details	binding site for residue 9A3 J 201

Chain	Residue
J	HIS16
J	MET19
J	LEU23
J	TYR82
J	TRP86
J	ILE105
J	TRP108
J	GLY109
J	LEU112
J	TRP129
J	TYR132
J	MET165
J	THR166
J	HIS169
J	TRP173
J	TYR184

site_id	AD2
Number of Residues	17
Details	binding site for residue 9A3 K 201

Chain	Residue
K	HIS16
K	MET19
K	MET36
K	LYS39
K	TYR82
K	TRP86
K	ILE105
K	TRP108
K	GLY109
K	LEU112
K	TRP129
K	TYR132
K	MET165
K	THR166
K	HIS169
K	TRP173
K	TYR184

site_id	AD3
Number of Residues	15
Details	binding site for residue 9A3 L 201

Chain	Residue
L	HIS16
L	MET19
L	TYR82
L	TRP86
L	ILE105
L	TRP108
L	GLY109
L	LEU112
L	TRP129
L	TYR132
L	MET165
L	THR166
L	HIS169
L	TRP173
L	TYR184

site_id	AD4
Number of Residues	16
Details	binding site for residue 9A3 M 201

Chain	Residue
M	HIS16
M	MET19
M	LYS39
M	TYR82
M	TRP86
M	ILE105
M	TRP108
M	GLY109
M	LEU112
M	TYR132
M	ILE138
M	MET165
M	THR166
M	HIS169
M	TRP173
M	TYR184

site_id	AD5
Number of Residues	16
Details	binding site for residue 9A3 N 201

Chain	Residue
N	HIS16
N	MET19
N	LYS39
N	TYR82
N	TRP86
N	ILE105
N	TRP108
N	GLY109
N	LEU112
N	TRP129
N	TYR132
N	MET165
N	THR166
N	HIS169
N	TRP173
N	TYR184

site_id	AD6
Number of Residues	15
Details	binding site for residue 9A3 O 201

Chain	Residue
O	HIS16
O	MET19
O	MET36
O	TYR82
O	TRP86
O	ILE105
O	TRP108
O	GLY109
O	LEU112
O	TYR132
O	MET165
O	THR166
O	HIS169
O	TRP173
O	TYR184

site_id	AD7
Number of Residues	15
Details	binding site for residue 9A3 P 201

Chain	Residue
P	HIS16
P	MET19
P	TYR82
P	TRP86
P	ILE105
P	TRP108
P	GLY109
P	LEU112
P	TRP129
P	TYR132
P	MET165
P	THR166
P	HIS169
P	TRP173
P	TYR184

Functional Information from PROSITE/UniProt

site_id	PS00018
Number of Residues	13
Details	EF_HAND_1 EF-hand calcium-binding domain. DVNHNGKISldEM

Chain	Residue	Details
A	ASP24-MET36
A	ASP117-TRP129
A	ASP153-MET165

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	560
Details	Domain: {"description":"EF-hand 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	864
Details	Domain: {"description":"EF-hand 2","evidences":[{"source":"PubMed","id":"10830969","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	464
Details	Domain: {"description":"EF-hand 3","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	560
Details	Domain: {"description":"EF-hand 4","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	480
Details	Region: {"description":"May interact with the chromophore"}

Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	224
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI7
Number of Residues	16
Details	Site: {"description":"Required for bioluminescence"}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)