5Z9M
Bacterial GyrB ATPase domain in complex with a chemical fragment
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003918 | molecular_function | DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006265 | biological_process | DNA topological change |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003918 | molecular_function | DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006265 | biological_process | DNA topological change |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue BZ2 A 301 |
| Chain | Residue |
| A | GLU50 |
| A | ARG76 |
| A | GLY77 |
| A | ARG136 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 302 |
| Chain | Residue |
| A | ARG204 |
| A | GLU213 |
| A | HIS215 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 303 |
| Chain | Residue |
| A | LYS208 |
| A | HOH406 |
| A | HOH412 |
| A | HIS64 |
| A | ARG168 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 304 |
| Chain | Residue |
| A | ARG192 |
| A | SO4305 |
| B | ALA152 |
| B | PRO153 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 305 |
| Chain | Residue |
| A | GLU193 |
| A | SO4304 |
| B | VAL88 |
| B | GLU92 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 A 306 |
| Chain | Residue |
| A | ARG206 |
| A | LYS208 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 307 |
| Chain | Residue |
| A | ARG22 |
| A | PRO23 |
| A | GLY24 |
| site_id | AC8 |
| Number of Residues | 1 |
| Details | binding site for residue SO4 A 308 |
| Chain | Residue |
| A | HIS83 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 A 309 |
| Chain | Residue |
| A | ARG142 |
| A | HOH404 |
| site_id | AD1 |
| Number of Residues | 4 |
| Details | binding site for residue BZ2 B 301 |
| Chain | Residue |
| B | GLU50 |
| B | ARG76 |
| B | GLY77 |
| B | ARG136 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 302 |
| Chain | Residue |
| A | THR177 |
| A | ASN178 |
| B | LYS129 |
| B | ARG142 |
| site_id | AD3 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 B 303 |
| Chain | Residue |
| B | ARG204 |
| B | HIS215 |
| site_id | AD4 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 B 304 |
| Chain | Residue |
| B | ARG206 |
| B | HOH405 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor (ATPase activity)","evidences":[{"source":"PubMed","id":"10734094","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"8248233","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"10734094","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25202966","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25849408","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"25849408","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
