5Z6U

Crystal structure of D-xylose reductase from Scheffersomyces stipitis

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016491	molecular_function	oxidoreductase activity
A	0032866	molecular_function	D-xylose reductase (NADPH) activity
A	0042843	biological_process	D-xylose catabolic process
B	0016491	molecular_function	oxidoreductase activity
B	0032866	molecular_function	D-xylose reductase (NADPH) activity
B	0042843	biological_process	D-xylose catabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue GOL A 401

Chain	Residue
A	TYR48
A	LYS77
A	HIS110
A	ASN166
A	GLN187
A	TYR213

---

site_id	AC2
Number of Residues	6
Details	binding site for residue GOL B 401

Chain	Residue
B	ASN166
B	GLN187
B	TYR213
B	TYR48
B	LYS77
B	HIS110

---

Functional Information from PROSITE/UniProt

site_id	PS00062
Number of Residues	18
Details	ALDOKETO_REDUCTASE_2 Aldo/keto reductase family signature 2. LeklvkagkIRSIGVSNF

Chain	Residue	Details
A	LEU150-PHE167

---

site_id	PS00063
Number of Residues	16
Details	ALDOKETO_REDUCTASE_3 Aldo/keto reductase family putative active site signature. IPKSNTvpRLlENkDV

Chain	Residue	Details
A	ILE268-VAL283

---

site_id	PS00798
Number of Residues	18
Details	ALDOKETO_REDUCTASE_1 Aldo/keto reductase family signature 1. GYRLFDGAedyanEklVG

Chain	Residue	Details
A	GLY38-GLY55

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Active site: {"description":"Proton donor","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	42
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	Site: {"description":"Lowers pKa of active site Tyr","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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