Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0032866 | molecular_function | D-xylose reductase (NADPH) activity |
| A | 0042843 | biological_process | D-xylose catabolic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0032866 | molecular_function | D-xylose reductase (NADPH) activity |
| B | 0042843 | biological_process | D-xylose catabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 31 |
| Details | binding site for residue NAP A 401 |
| Chain | Residue |
| A | GLY18 |
| A | GLN187 |
| A | TYR213 |
| A | SER214 |
| A | SER215 |
| A | PHE216 |
| A | GLN219 |
| A | SER220 |
| A | GLU223 |
| A | PHE236 |
| A | ALA253 |
| A | CYS19 |
| A | ILE268 |
| A | PRO269 |
| A | LYS270 |
| A | ASN272 |
| A | ARG276 |
| A | GLU279 |
| A | ASN280 |
| A | ASN306 |
| A | HOH530 |
| A | HOH543 |
| A | TRP20 |
| A | HOH544 |
| A | HOH561 |
| A | ASP43 |
| A | TYR48 |
| A | LYS77 |
| A | HIS110 |
| A | SER165 |
| A | ASN166 |
| site_id | AC2 |
| Number of Residues | 21 |
| Details | binding site for residue NAP B 401 |
| Chain | Residue |
| B | TRP20 |
| B | LYS21 |
| B | TYR48 |
| B | HIS110 |
| B | SER165 |
| B | ASN166 |
| B | GLN187 |
| B | TYR213 |
| B | SER214 |
| B | SER215 |
| B | PHE216 |
| B | GLY217 |
| B | PHE236 |
| B | ALA253 |
| B | LYS270 |
| B | ASN272 |
| B | ARG276 |
| B | GLU279 |
| B | ASN280 |
| B | ASN306 |
| B | HOH501 |
Functional Information from PROSITE/UniProt
| site_id | PS00062 |
| Number of Residues | 18 |
| Details | ALDOKETO_REDUCTASE_2 Aldo/keto reductase family signature 2. LeklvkagkIRSIGVSNF |
| Chain | Residue | Details |
| A | LEU150-PHE167 | |
| site_id | PS00063 |
| Number of Residues | 16 |
| Details | ALDOKETO_REDUCTASE_3 Aldo/keto reductase family putative active site signature. IPKSNTvpRLlENkDV |
| Chain | Residue | Details |
| A | ILE268-VAL283 | |
| site_id | PS00798 |
| Number of Residues | 18 |
| Details | ALDOKETO_REDUCTASE_1 Aldo/keto reductase family signature 1. GYRLFDGAedyanEklVG |
| Chain | Residue | Details |
| A | GLY38-GLY55 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 42 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Site: {"description":"Lowers pKa of active site Tyr","evidences":[{"evidenceCode":"ECO:0000250"}]} |
5Z6T
