5Z5B
Crystal structure of Tk-PTP in the G95A mutant form
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004721 | molecular_function | phosphoprotein phosphatase activity |
| A | 0004725 | molecular_function | protein tyrosine phosphatase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006470 | biological_process | protein dephosphorylation |
| A | 0016311 | biological_process | dephosphorylation |
| B | 0004721 | molecular_function | phosphoprotein phosphatase activity |
| B | 0004725 | molecular_function | protein tyrosine phosphatase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006470 | biological_process | protein dephosphorylation |
| B | 0016311 | biological_process | dephosphorylation |
| C | 0004721 | molecular_function | phosphoprotein phosphatase activity |
| C | 0004725 | molecular_function | protein tyrosine phosphatase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0006470 | biological_process | protein dephosphorylation |
| C | 0016311 | biological_process | dephosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 1 |
| Details | binding site for residue CL A 201 |
| Chain | Residue |
| A | ARG146 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue FMT A 202 |
| Chain | Residue |
| A | ASP63 |
| A | CYS93 |
| A | MET94 |
| A | ALA95 |
| A | GLY98 |
| A | ARG99 |
| C | ARG117 |
| site_id | AC3 |
| Number of Residues | 1 |
| Details | binding site for residue CL B 201 |
| Chain | Residue |
| B | TYR110 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue FMT B 202 |
| Chain | Residue |
| A | ARG117 |
| B | ASP63 |
| B | CYS93 |
| B | MET94 |
| B | ALA95 |
| B | ARG99 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | binding site for residue FMT C 201 |
| Chain | Residue |
| B | ARG117 |
| C | ASP63 |
| C | CYS93 |
| C | MET94 |
| C | ALA95 |
| C | GLY96 |
| C | GLY98 |
| C | ARG99 |
Functional Information from PROSITE/UniProt
| site_id | PS00383 |
| Number of Residues | 11 |
| Details | TYR_PHOSPHATASE_1 Tyrosine specific protein phosphatases active site. IHCmaGlgRSG |
| Chain | Residue | Details |
| A | ILE91-GLY101 |
