5Z2M

Structure of Orp1L/Rab7 complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003924	molecular_function	GTPase activity
A	0005525	molecular_function	GTP binding
C	0003924	molecular_function	GTPase activity
C	0005525	molecular_function	GTP binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue MG A 201

Chain	Residue
A	THR22
A	THR40
A	GTP202
A	HOH313

---

site_id	AC2
Number of Residues	23
Details	binding site for residue GTP A 202

Chain	Residue
A	THR22
A	SER23
A	PHE33
A	SER34
A	ASN35
A	TYR37
A	THR40
A	GLY66
A	ASN125
A	LYS126
A	ASP128
A	LEU129
A	SER155
A	ALA156
A	LYS157
A	MG201
A	HOH313
A	HOH325
A	SER17
A	GLY18
A	VAL19
A	GLY20
A	LYS21

---

site_id	AC3
Number of Residues	21
Details	binding site for residue GTP C 201

Chain	Residue
C	SER17
C	GLY18
C	VAL19
C	GLY20
C	LYS21
C	THR22
C	SER23
C	PHE33
C	ASN35
C	GLN36
C	ASP63
C	THR64
C	GLU68
C	ASN125
C	LYS126
C	ASP128
C	LEU129
C	SER155
C	ALA156
C	LYS157
C	HOH301

---

Functional Information from PROSITE/UniProt

site_id	PS00675
Number of Residues	14
Details	SIGMA54_INTERACT_1 Sigma-54 interaction domain ATP-binding region A signature. VIIlGDSGVGKtsL

Chain	Residue	Details
A	VAL11-LEU24

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	36
Details	BINDING: BINDING => ECO:0000250|UniProtKB:P51149

Chain	Residue	Details
A	SER17
A	TYR37
A	THR40
A	ASP63
A	GLY66
A	ASN125
A	LYS126
A	ASP128
A	ALA156
A	LYS157
C	SER17
A	GLY18
C	GLY18
C	VAL19
C	GLY20
C	LYS21
C	THR22
C	SER23
C	SER34
C	ASN35
C	TYR37
C	THR40
A	VAL19
C	ASP63
C	GLY66
C	ASN125
C	LYS126
C	ASP128
C	ALA156
C	LYS157
A	GLY20
A	LYS21
A	THR22
A	SER23
A	SER34
A	ASN35

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	MOD_RES: N-acetylthreonine => ECO:0000250|UniProtKB:P51149

Chain	Residue	Details
A	THR2
C	THR2

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:19144319, ECO:0007744|PubMed:21183079

Chain	Residue	Details
A	SER72
C	SER72

---