5Z2C

Crystal structure of ALPK-1 N-terminal domain in complex with ADP-heptose

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004674	molecular_function	protein serine/threonine kinase activity
B	0004674	molecular_function	protein serine/threonine kinase activity
C	0004674	molecular_function	protein serine/threonine kinase activity
D	0004674	molecular_function	protein serine/threonine kinase activity
E	0004674	molecular_function	protein serine/threonine kinase activity
F	0004674	molecular_function	protein serine/threonine kinase activity
G	0004674	molecular_function	protein serine/threonine kinase activity
H	0004674	molecular_function	protein serine/threonine kinase activity
I	0004674	molecular_function	protein serine/threonine kinase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	16
Details	binding site for residue AYU A 501

Chain	Residue
A	PHE61
A	TYR224
A	ASP231
A	LYS233
A	GLY234
A	SER236
A	THR237
A	PHE295
A	GLN67
A	TYR68
A	ARG116
A	GLN146
A	ARG150
A	ARG153
A	VAL195
A	GLN198

---

site_id	AC2
Number of Residues	17
Details	binding site for residue AYU B 501

Chain	Residue
B	PHE61
B	GLN67
B	TYR68
B	ARG116
B	TYR119
B	GLN146
B	ARG150
B	ARG153
B	VAL195
B	GLN198
B	TYR224
B	ASP231
B	LYS233
B	GLY234
B	SER236
B	THR237
B	PHE295

---

site_id	AC3
Number of Residues	16
Details	binding site for residue AYU C 501

Chain	Residue
C	PHE61
C	GLN67
C	ARG116
C	TYR119
C	GLN146
C	ARG150
C	ARG153
C	VAL195
C	GLN198
C	TYR224
C	ASP231
C	LYS233
C	GLY234
C	SER236
C	THR237
C	PHE295

---

site_id	AC4
Number of Residues	16
Details	binding site for residue AYU D 501

Chain	Residue
D	PHE61
D	GLN67
D	ARG116
D	TYR119
D	GLN146
D	ARG150
D	ARG153
D	VAL195
D	GLN198
D	TYR224
D	ASP231
D	LYS233
D	GLY234
D	SER236
D	THR237
D	PHE295

---

site_id	AC5
Number of Residues	17
Details	binding site for residue AYU E 501

Chain	Residue
E	PHE61
E	GLN67
E	TYR68
E	ARG116
E	TYR119
E	GLN146
E	ARG150
E	ARG153
E	VAL195
E	GLN198
E	TYR224
E	ASP231
E	LYS233
E	GLY234
E	SER236
E	THR237
E	PHE295

---

site_id	AC6
Number of Residues	17
Details	binding site for residue AYU F 501

Chain	Residue
F	PHE61
F	GLN67
F	TYR68
F	ARG116
F	TYR119
F	GLN146
F	ARG150
F	ARG153
F	VAL195
F	GLN198
F	TYR224
F	ASP231
F	LYS233
F	GLY234
F	SER236
F	THR237
F	PHE295

---

site_id	AC7
Number of Residues	16
Details	binding site for residue AYU G 501

Chain	Residue
G	PHE61
G	ARG116
G	TYR119
G	GLN146
G	ARG150
G	ARG153
G	VAL195
G	GLN198
G	TYR224
G	ASP231
G	LYS233
G	GLY234
G	SER236
G	THR237
G	SER289
G	PHE295

---

site_id	AC8
Number of Residues	16
Details	binding site for residue AYU H 501

Chain	Residue
H	PHE61
H	ARG116
H	TYR119
H	GLN146
H	ILE149
H	ARG150
H	ARG153
H	VAL195
H	GLN198
H	TYR224
H	ASP231
H	LYS233
H	GLY234
H	SER236
H	THR237
H	PHE295

---

site_id	AC9
Number of Residues	15
Details	binding site for residue AYU I 501

Chain	Residue
I	PHE61
I	GLN67
I	ARG116
I	TYR119
I	GLN146
I	ARG150
I	ARG153
I	VAL195
I	TYR224
I	ASP231
I	LYS233
I	GLY234
I	SER236
I	THR237
I	PHE295

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	88
Details	Binding site: {"evidences":[{"source":"PubMed","id":"30111836","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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