5Z2C
Crystal structure of ALPK-1 N-terminal domain in complex with ADP-heptose
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004674 | molecular_function | protein serine/threonine kinase activity |
| B | 0004674 | molecular_function | protein serine/threonine kinase activity |
| C | 0004674 | molecular_function | protein serine/threonine kinase activity |
| D | 0004674 | molecular_function | protein serine/threonine kinase activity |
| E | 0004674 | molecular_function | protein serine/threonine kinase activity |
| F | 0004674 | molecular_function | protein serine/threonine kinase activity |
| G | 0004674 | molecular_function | protein serine/threonine kinase activity |
| H | 0004674 | molecular_function | protein serine/threonine kinase activity |
| I | 0004674 | molecular_function | protein serine/threonine kinase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | binding site for residue AYU A 501 |
| Chain | Residue |
| A | PHE61 |
| A | TYR224 |
| A | ASP231 |
| A | LYS233 |
| A | GLY234 |
| A | SER236 |
| A | THR237 |
| A | PHE295 |
| A | GLN67 |
| A | TYR68 |
| A | ARG116 |
| A | GLN146 |
| A | ARG150 |
| A | ARG153 |
| A | VAL195 |
| A | GLN198 |
| site_id | AC2 |
| Number of Residues | 17 |
| Details | binding site for residue AYU B 501 |
| Chain | Residue |
| B | PHE61 |
| B | GLN67 |
| B | TYR68 |
| B | ARG116 |
| B | TYR119 |
| B | GLN146 |
| B | ARG150 |
| B | ARG153 |
| B | VAL195 |
| B | GLN198 |
| B | TYR224 |
| B | ASP231 |
| B | LYS233 |
| B | GLY234 |
| B | SER236 |
| B | THR237 |
| B | PHE295 |
| site_id | AC3 |
| Number of Residues | 16 |
| Details | binding site for residue AYU C 501 |
| Chain | Residue |
| C | PHE61 |
| C | GLN67 |
| C | ARG116 |
| C | TYR119 |
| C | GLN146 |
| C | ARG150 |
| C | ARG153 |
| C | VAL195 |
| C | GLN198 |
| C | TYR224 |
| C | ASP231 |
| C | LYS233 |
| C | GLY234 |
| C | SER236 |
| C | THR237 |
| C | PHE295 |
| site_id | AC4 |
| Number of Residues | 16 |
| Details | binding site for residue AYU D 501 |
| Chain | Residue |
| D | PHE61 |
| D | GLN67 |
| D | ARG116 |
| D | TYR119 |
| D | GLN146 |
| D | ARG150 |
| D | ARG153 |
| D | VAL195 |
| D | GLN198 |
| D | TYR224 |
| D | ASP231 |
| D | LYS233 |
| D | GLY234 |
| D | SER236 |
| D | THR237 |
| D | PHE295 |
| site_id | AC5 |
| Number of Residues | 17 |
| Details | binding site for residue AYU E 501 |
| Chain | Residue |
| E | PHE61 |
| E | GLN67 |
| E | TYR68 |
| E | ARG116 |
| E | TYR119 |
| E | GLN146 |
| E | ARG150 |
| E | ARG153 |
| E | VAL195 |
| E | GLN198 |
| E | TYR224 |
| E | ASP231 |
| E | LYS233 |
| E | GLY234 |
| E | SER236 |
| E | THR237 |
| E | PHE295 |
| site_id | AC6 |
| Number of Residues | 17 |
| Details | binding site for residue AYU F 501 |
| Chain | Residue |
| F | PHE61 |
| F | GLN67 |
| F | TYR68 |
| F | ARG116 |
| F | TYR119 |
| F | GLN146 |
| F | ARG150 |
| F | ARG153 |
| F | VAL195 |
| F | GLN198 |
| F | TYR224 |
| F | ASP231 |
| F | LYS233 |
| F | GLY234 |
| F | SER236 |
| F | THR237 |
| F | PHE295 |
| site_id | AC7 |
| Number of Residues | 16 |
| Details | binding site for residue AYU G 501 |
| Chain | Residue |
| G | PHE61 |
| G | ARG116 |
| G | TYR119 |
| G | GLN146 |
| G | ARG150 |
| G | ARG153 |
| G | VAL195 |
| G | GLN198 |
| G | TYR224 |
| G | ASP231 |
| G | LYS233 |
| G | GLY234 |
| G | SER236 |
| G | THR237 |
| G | SER289 |
| G | PHE295 |
| site_id | AC8 |
| Number of Residues | 16 |
| Details | binding site for residue AYU H 501 |
| Chain | Residue |
| H | PHE61 |
| H | ARG116 |
| H | TYR119 |
| H | GLN146 |
| H | ILE149 |
| H | ARG150 |
| H | ARG153 |
| H | VAL195 |
| H | GLN198 |
| H | TYR224 |
| H | ASP231 |
| H | LYS233 |
| H | GLY234 |
| H | SER236 |
| H | THR237 |
| H | PHE295 |
| site_id | AC9 |
| Number of Residues | 15 |
| Details | binding site for residue AYU I 501 |
| Chain | Residue |
| I | PHE61 |
| I | GLN67 |
| I | ARG116 |
| I | TYR119 |
| I | GLN146 |
| I | ARG150 |
| I | ARG153 |
| I | VAL195 |
| I | TYR224 |
| I | ASP231 |
| I | LYS233 |
| I | GLY234 |
| I | SER236 |
| I | THR237 |
| I | PHE295 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 72 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:30111836 |
| Chain | Residue | Details |
| A | PHE61 | |
| B | GLN67 | |
| B | ARG116 | |
| B | ARG150 | |
| B | ASP231 | |
| B | LYS233 | |
| B | SER236 | |
| B | PHE295 | |
| C | PHE61 | |
| C | GLN67 | |
| C | ARG116 | |
| A | GLN67 | |
| C | ARG150 | |
| C | ASP231 | |
| C | LYS233 | |
| C | SER236 | |
| C | PHE295 | |
| D | PHE61 | |
| D | GLN67 | |
| D | ARG116 | |
| D | ARG150 | |
| D | ASP231 | |
| A | ARG116 | |
| D | LYS233 | |
| D | SER236 | |
| D | PHE295 | |
| E | PHE61 | |
| E | GLN67 | |
| E | ARG116 | |
| E | ARG150 | |
| E | ASP231 | |
| E | LYS233 | |
| E | SER236 | |
| A | ARG150 | |
| E | PHE295 | |
| F | PHE61 | |
| F | GLN67 | |
| F | ARG116 | |
| F | ARG150 | |
| F | ASP231 | |
| F | LYS233 | |
| F | SER236 | |
| F | PHE295 | |
| G | PHE61 | |
| A | ASP231 | |
| G | GLN67 | |
| G | ARG116 | |
| G | ARG150 | |
| G | ASP231 | |
| G | LYS233 | |
| G | SER236 | |
| G | PHE295 | |
| H | PHE61 | |
| H | GLN67 | |
| H | ARG116 | |
| A | LYS233 | |
| H | ARG150 | |
| H | ASP231 | |
| H | LYS233 | |
| H | SER236 | |
| H | PHE295 | |
| I | PHE61 | |
| I | GLN67 | |
| I | ARG116 | |
| I | ARG150 | |
| I | ASP231 | |
| A | SER236 | |
| I | LYS233 | |
| I | SER236 | |
| I | PHE295 | |
| A | PHE295 | |
| B | PHE61 |
