5Z2B
Crystal structure of highly active BTUO mutant P287G Improved by Humidity Control at 86% RH
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | binding site for residue AZA A 401 |
| Chain | Residue |
| A | PHE184 |
| B | ALA72 |
| B | THR73 |
| A | LEU195 |
| A | ARG201 |
| A | SER248 |
| A | ILE249 |
| A | GLN250 |
| A | ASN276 |
| A | OXY403 |
| A | HOH579 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 A 402 |
| Chain | Residue |
| A | ARG298 |
| B | ARG298 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue OXY A 403 |
| Chain | Residue |
| A | ASN276 |
| A | GLY302 |
| A | GLN304 |
| A | AZA401 |
| B | THR73 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue OXY B 401 |
| Chain | Residue |
| A | THR73 |
| B | ASN276 |
| B | GLY302 |
| B | GLN304 |
| B | AZA402 |
| site_id | AC5 |
| Number of Residues | 10 |
| Details | binding site for residue AZA B 402 |
| Chain | Residue |
| A | ALA72 |
| A | THR73 |
| B | PHE184 |
| B | ARG201 |
| B | SER248 |
| B | ILE249 |
| B | GLN250 |
| B | ASN276 |
| B | OXY401 |
| B | HOH583 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue CL B 403 |
| Chain | Residue |
| B | ILE32 |
| B | SER35 |
| B | SER38 |
| B | ARG133 |
| B | HOH537 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 404 |
| Chain | Residue |
| B | GLU119 |
| B | ALA230 |
| B | GLU231 |
| B | ARG234 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 405 |
| Chain | Residue |
| B | HIS42 |
| B | ILE43 |
| B | LEU44 |
| B | PHE140 |
| B | HOH596 |
| B | HOH623 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 406 |
| Chain | Residue |
| B | GLU123 |
| B | SER143 |
| B | ASN145 |
| B | GLU146 |
| B | HOH539 |
Functional Information from PROSITE/UniProt
| site_id | PS00366 |
| Number of Residues | 28 |
| Details | URICASE Uricase signature. LqLIKVSgNsFvgFirdeYttLpedsnR |
| Chain | Residue | Details |
| A | LEU174-ARG201 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Active site: {"description":"Charge relay system; for urate oxidase activity","evidences":[{"source":"UniProtKB","id":"D0VWQ1","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Charge relay system","evidences":[{"source":"UniProtKB","id":"Q00511","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"Q00511","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"Reference","evidenceCode":"ECO:0000305","citation":{"citationType":"submission","publicationDate":"FEB-2009","submissionDatabase":"PDB data bank","title":"Crystal structure of urate oxidase from Bacillus sp.","authoringGroup":["Mycobacterium tuberculosis structural genomics consortium (TB)"]}}]} |
| Chain | Residue | Details |
