5Z1W
Cryo-EM structure of polycystic kidney disease-like channel PKD2L1
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005509 | molecular_function | calcium ion binding |
| A | 0016020 | cellular_component | membrane |
| B | 0005509 | molecular_function | calcium ion binding |
| B | 0016020 | cellular_component | membrane |
| C | 0005509 | molecular_function | calcium ion binding |
| C | 0016020 | cellular_component | membrane |
| D | 0005509 | molecular_function | calcium ion binding |
| D | 0016020 | cellular_component | membrane |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 472 |
| Details | TRANSMEM: Helical => ECO:0000305|PubMed:29567962 |
| Chain | Residue | Details |
| A | LEU104-SER124 | |
| B | TRP434-PHE454 | |
| B | PHE480-PHE499 | |
| B | GLY537-LEU557 | |
| C | LEU104-SER124 | |
| C | VAL357-LEU376 | |
| C | VAL385-ILE405 | |
| C | TRP434-PHE454 | |
| C | PHE480-PHE499 | |
| C | GLY537-LEU557 | |
| D | LEU104-SER124 | |
| A | VAL357-LEU376 | |
| D | VAL357-LEU376 | |
| D | VAL385-ILE405 | |
| D | TRP434-PHE454 | |
| D | PHE480-PHE499 | |
| D | GLY537-LEU557 | |
| A | VAL385-ILE405 | |
| A | TRP434-PHE454 | |
| A | PHE480-PHE499 | |
| A | GLY537-LEU557 | |
| B | LEU104-SER124 | |
| B | VAL357-LEU376 | |
| B | VAL385-ILE405 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1112 |
| Details | TOPO_DOM: Extracellular => ECO:0000305|PubMed:29567962 |
| Chain | Residue | Details |
| A | SER125-GLU356 | |
| C | PHE406-PHE433 | |
| C | GLY500-LYS511 | |
| C | ASN527-LEU536 | |
| D | SER125-GLU356 | |
| D | PHE406-PHE433 | |
| D | GLY500-LYS511 | |
| D | ASN527-LEU536 | |
| A | PHE406-PHE433 | |
| A | GLY500-LYS511 | |
| A | ASN527-LEU536 | |
| B | SER125-GLU356 | |
| B | PHE406-PHE433 | |
| B | GLY500-LYS511 | |
| B | ASN527-LEU536 | |
| C | SER125-GLU356 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 124 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000305|PubMed:29567962 |
| Chain | Residue | Details |
| A | HIS377-SER384 | |
| A | LYS455-GLY479 | |
| B | HIS377-SER384 | |
| B | LYS455-GLY479 | |
| C | HIS377-SER384 | |
| C | LYS455-GLY479 | |
| D | HIS377-SER384 | |
| D | LYS455-GLY479 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 56 |
| Details | INTRAMEM: Pore-forming => ECO:0000305|PubMed:29567962 |
| Chain | Residue | Details |
| A | CYS512-TYR526 | |
| B | CYS512-TYR526 | |
| C | CYS512-TYR526 | |
| D | CYS512-TYR526 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 12 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:29567962, ECO:0007744|PDB:5Z1W |
| Chain | Residue | Details |
| A | ASN177 | |
| D | ASN177 | |
| D | ASN207 | |
| D | ASN241 | |
| A | ASN207 | |
| A | ASN241 | |
| B | ASN177 | |
| B | ASN207 | |
| B | ASN241 | |
| C | ASN177 | |
| C | ASN207 | |
| C | ASN241 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 4 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN505 | |
| B | ASN505 | |
| C | ASN505 | |
| D | ASN505 |
