Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

5Z09

ST0452(Y97N)-UTP binding form

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0003977	molecular_function	UDP-N-acetylglucosamine diphosphorylase activity
A	0003983	molecular_function	UTP:glucose-1-phosphate uridylyltransferase activity
A	0006048	biological_process	UDP-N-acetylglucosamine biosynthetic process
A	0008879	molecular_function	glucose-1-phosphate thymidylyltransferase activity
A	0009058	biological_process	biosynthetic process
A	0016746	molecular_function	acyltransferase activity
A	0016779	molecular_function	nucleotidyltransferase activity
A	0019134	molecular_function	glucosamine-1-phosphate N-acetyltransferase activity
A	0052630	molecular_function	UDP-N-acetylgalactosamine diphosphorylase activity
B	0000166	molecular_function	nucleotide binding
B	0003977	molecular_function	UDP-N-acetylglucosamine diphosphorylase activity
B	0003983	molecular_function	UTP:glucose-1-phosphate uridylyltransferase activity
B	0006048	biological_process	UDP-N-acetylglucosamine biosynthetic process
B	0008879	molecular_function	glucose-1-phosphate thymidylyltransferase activity
B	0009058	biological_process	biosynthetic process
B	0016746	molecular_function	acyltransferase activity
B	0016779	molecular_function	nucleotidyltransferase activity
B	0019134	molecular_function	glucosamine-1-phosphate N-acetyltransferase activity
B	0052630	molecular_function	UDP-N-acetylgalactosamine diphosphorylase activity
C	0000166	molecular_function	nucleotide binding
C	0003977	molecular_function	UDP-N-acetylglucosamine diphosphorylase activity
C	0003983	molecular_function	UTP:glucose-1-phosphate uridylyltransferase activity
C	0006048	biological_process	UDP-N-acetylglucosamine biosynthetic process
C	0008879	molecular_function	glucose-1-phosphate thymidylyltransferase activity
C	0009058	biological_process	biosynthetic process
C	0016746	molecular_function	acyltransferase activity
C	0016779	molecular_function	nucleotidyltransferase activity
C	0019134	molecular_function	glucosamine-1-phosphate N-acetyltransferase activity
C	0052630	molecular_function	UDP-N-acetylgalactosamine diphosphorylase activity
D	0000166	molecular_function	nucleotide binding
D	0003977	molecular_function	UDP-N-acetylglucosamine diphosphorylase activity
D	0003983	molecular_function	UTP:glucose-1-phosphate uridylyltransferase activity
D	0006048	biological_process	UDP-N-acetylglucosamine biosynthetic process
D	0008879	molecular_function	glucose-1-phosphate thymidylyltransferase activity
D	0009058	biological_process	biosynthetic process
D	0016746	molecular_function	acyltransferase activity
D	0016779	molecular_function	nucleotidyltransferase activity
D	0019134	molecular_function	glucosamine-1-phosphate N-acetyltransferase activity
D	0052630	molecular_function	UDP-N-acetylgalactosamine diphosphorylase activity
E	0000166	molecular_function	nucleotide binding
E	0003977	molecular_function	UDP-N-acetylglucosamine diphosphorylase activity
E	0003983	molecular_function	UTP:glucose-1-phosphate uridylyltransferase activity
E	0006048	biological_process	UDP-N-acetylglucosamine biosynthetic process
E	0008879	molecular_function	glucose-1-phosphate thymidylyltransferase activity
E	0009058	biological_process	biosynthetic process
E	0016746	molecular_function	acyltransferase activity
E	0016779	molecular_function	nucleotidyltransferase activity
E	0019134	molecular_function	glucosamine-1-phosphate N-acetyltransferase activity
E	0052630	molecular_function	UDP-N-acetylgalactosamine diphosphorylase activity
F	0000166	molecular_function	nucleotide binding
F	0003977	molecular_function	UDP-N-acetylglucosamine diphosphorylase activity
F	0003983	molecular_function	UTP:glucose-1-phosphate uridylyltransferase activity
F	0006048	biological_process	UDP-N-acetylglucosamine biosynthetic process
F	0008879	molecular_function	glucose-1-phosphate thymidylyltransferase activity
F	0009058	biological_process	biosynthetic process
F	0016746	molecular_function	acyltransferase activity
F	0016779	molecular_function	nucleotidyltransferase activity
F	0019134	molecular_function	glucosamine-1-phosphate N-acetyltransferase activity
F	0052630	molecular_function	UDP-N-acetylgalactosamine diphosphorylase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	15
Details	binding site for residue UTP A 501

Chain	Residue
A	LEU6
A	GLN73
A	GLY79
A	THR80
A	GLY98
A	ASP99
A	ARG179
A	ALA7
A	ALA8
A	GLY9
A	SER10
A	GLY11
A	GLU12
A	ARG13
A	LYS23

site_id	AC2
Number of Residues	15
Details	binding site for residue UTP B 501

Chain	Residue
B	LEU6
B	ALA7
B	ALA8
B	GLY9
B	GLY11
B	ARG13
B	LYS23
B	GLN73
B	GLY79
B	THR80
B	ALA83
B	ASN97
B	GLY98
B	ASP99
B	ARG179

site_id	AC3
Number of Residues	14
Details	binding site for residue UTP C 501

Chain	Residue
C	LEU6
C	ALA7
C	ALA8
C	GLY9
C	SER10
C	GLY11
C	GLU12
C	ARG13
C	LYS23
C	GLN73
C	GLY79
C	THR80
C	GLY98
C	ASP99

site_id	AC4
Number of Residues	14
Details	binding site for residue UTP D 501

Chain	Residue
D	LEU6
D	ALA7
D	ALA8
D	GLY9
D	SER10
D	GLY11
D	GLU12
D	ARG13
D	GLN73
D	LYS78
D	GLY79
D	THR80
D	GLY98
D	ASP99

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	18
Details	BINDING: BINDING => ECO:0000269\|PubMed:30291121, ECO:0000269\|Ref.6

Chain	Residue	Details
A	ALA8
D	ALA8
D	GLN73
D	GLY79
E	ALA8
E	GLN73
E	GLY79
F	ALA8
F	GLN73
F	GLY79
A	GLN73
A	GLY79
B	ALA8
B	GLN73
B	GLY79
C	ALA8
C	GLN73
C	GLY79

site_id	SWS_FT_FI2
Number of Residues	30
Details	BINDING: BINDING => ECO:0000305\|PubMed:30291121, ECO:0007744\|PDB:5Z0A

Chain	Residue	Details
A	THR80
B	ASN157
C	THR80
C	ASN97
C	GLY131
C	GLU146
C	ASN157
D	THR80
D	ASN97
D	GLY131
D	GLU146
A	ASN97
D	ASN157
E	THR80
E	ASN97
E	GLY131
E	GLU146
E	ASN157
F	THR80
F	ASN97
F	GLY131
F	GLU146
A	GLY131
F	ASN157
A	GLU146
A	ASN157
B	THR80
B	ASN97
B	GLY131
B	GLU146

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)