5YWB

Structure of pancreatic ATP-sensitive potassium channel bound with Mg-ADP (CTD class2 at 5.2A)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001508	biological_process	action potential
A	0001666	biological_process	response to hypoxia
A	0001669	cellular_component	acrosomal vesicle
A	0002931	biological_process	response to ischemia
A	0003229	biological_process	ventricular cardiac muscle tissue development
A	0005242	molecular_function	inward rectifier potassium channel activity
A	0005249	molecular_function	voltage-gated potassium channel activity
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005635	cellular_component	nuclear envelope
A	0005737	cellular_component	cytoplasm
A	0005768	cellular_component	endosome
A	0005886	cellular_component	plasma membrane
A	0006006	biological_process	glucose metabolic process
A	0006813	biological_process	potassium ion transport
A	0006915	biological_process	apoptotic process
A	0006950	biological_process	response to stress
A	0008282	cellular_component	inward rectifying potassium channel
A	0008340	biological_process	determination of adult lifespan
A	0009410	biological_process	response to xenobiotic stimulus
A	0014704	cellular_component	intercalated disc
A	0015272	molecular_function	ATP-activated inward rectifier potassium channel activity
A	0016020	cellular_component	membrane
A	0019829	molecular_function	ATPase-coupled monoatomic cation transmembrane transporter activity
A	0030315	cellular_component	T-tubule
A	0030506	molecular_function	ankyrin binding
A	0030673	cellular_component	axolemma
A	0030955	molecular_function	potassium ion binding
A	0031072	molecular_function	heat shock protein binding
A	0031669	biological_process	cellular response to nutrient levels
A	0032355	biological_process	response to estradiol
A	0033198	biological_process	response to ATP
A	0033574	biological_process	response to testosterone
A	0034220	biological_process	monoatomic ion transmembrane transport
A	0034702	cellular_component	monoatomic ion channel complex
A	0042383	cellular_component	sarcolemma
A	0042391	biological_process	regulation of membrane potential
A	0042734	cellular_component	presynaptic membrane
A	0043025	cellular_component	neuronal cell body
A	0044325	molecular_function	transmembrane transporter binding
A	0046676	biological_process	negative regulation of insulin secretion
A	0050796	biological_process	regulation of insulin secretion
A	0050877	biological_process	nervous system process
A	0061762	biological_process	CAMKK-AMPK signaling cascade
A	0070852	cellular_component	cell body fiber
A	0071316	biological_process	cellular response to nicotine
A	0071333	biological_process	cellular response to glucose stimulus
A	0071356	biological_process	cellular response to tumor necrosis factor
A	0071805	biological_process	potassium ion transmembrane transport
A	0098662	biological_process	inorganic cation transmembrane transport
A	0098978	cellular_component	glutamatergic synapse
A	0099505	biological_process	regulation of presynaptic membrane potential
A	0099508	molecular_function	voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential
A	1903078	biological_process	positive regulation of protein localization to plasma membrane
A	1904638	biological_process	response to resveratrol
A	1990573	biological_process	potassium ion import across plasma membrane
B	0005267	molecular_function	potassium channel activity
B	0005524	molecular_function	ATP binding
B	0005886	cellular_component	plasma membrane
B	0006813	biological_process	potassium ion transport
B	0008281	molecular_function	sulfonylurea receptor activity
B	0016020	cellular_component	membrane
B	0016887	molecular_function	ATP hydrolysis activity
B	0032991	cellular_component	protein-containing complex
B	0042626	molecular_function	ATPase-coupled transmembrane transporter activity
B	0055085	biological_process	transmembrane transport
B	0071805	biological_process	potassium ion transmembrane transport
B	0140359	molecular_function	ABC-type transporter activity
C	0001508	biological_process	action potential
C	0001666	biological_process	response to hypoxia
C	0001669	cellular_component	acrosomal vesicle
C	0002931	biological_process	response to ischemia
C	0003229	biological_process	ventricular cardiac muscle tissue development
C	0005242	molecular_function	inward rectifier potassium channel activity
C	0005249	molecular_function	voltage-gated potassium channel activity
C	0005515	molecular_function	protein binding
C	0005524	molecular_function	ATP binding
C	0005635	cellular_component	nuclear envelope
C	0005737	cellular_component	cytoplasm
C	0005768	cellular_component	endosome
C	0005886	cellular_component	plasma membrane
C	0006006	biological_process	glucose metabolic process
C	0006813	biological_process	potassium ion transport
C	0006915	biological_process	apoptotic process
C	0006950	biological_process	response to stress
C	0008282	cellular_component	inward rectifying potassium channel
C	0008340	biological_process	determination of adult lifespan
C	0009410	biological_process	response to xenobiotic stimulus
C	0014704	cellular_component	intercalated disc
C	0015272	molecular_function	ATP-activated inward rectifier potassium channel activity
C	0016020	cellular_component	membrane
C	0019829	molecular_function	ATPase-coupled monoatomic cation transmembrane transporter activity
C	0030315	cellular_component	T-tubule
C	0030506	molecular_function	ankyrin binding
C	0030673	cellular_component	axolemma
C	0030955	molecular_function	potassium ion binding
C	0031072	molecular_function	heat shock protein binding
C	0031669	biological_process	cellular response to nutrient levels
C	0032355	biological_process	response to estradiol
C	0033198	biological_process	response to ATP
C	0033574	biological_process	response to testosterone
C	0034220	biological_process	monoatomic ion transmembrane transport
C	0034702	cellular_component	monoatomic ion channel complex
C	0042383	cellular_component	sarcolemma
C	0042391	biological_process	regulation of membrane potential
C	0042734	cellular_component	presynaptic membrane
C	0043025	cellular_component	neuronal cell body
C	0044325	molecular_function	transmembrane transporter binding
C	0046676	biological_process	negative regulation of insulin secretion
C	0050796	biological_process	regulation of insulin secretion
C	0050877	biological_process	nervous system process
C	0061762	biological_process	CAMKK-AMPK signaling cascade
C	0070852	cellular_component	cell body fiber
C	0071316	biological_process	cellular response to nicotine
C	0071333	biological_process	cellular response to glucose stimulus
C	0071356	biological_process	cellular response to tumor necrosis factor
C	0071805	biological_process	potassium ion transmembrane transport
C	0098662	biological_process	inorganic cation transmembrane transport
C	0098978	cellular_component	glutamatergic synapse
C	0099505	biological_process	regulation of presynaptic membrane potential
C	0099508	molecular_function	voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential
C	1903078	biological_process	positive regulation of protein localization to plasma membrane
C	1904638	biological_process	response to resveratrol
C	1990573	biological_process	potassium ion import across plasma membrane
D	0005267	molecular_function	potassium channel activity
D	0005524	molecular_function	ATP binding
D	0005886	cellular_component	plasma membrane
D	0006813	biological_process	potassium ion transport
D	0008281	molecular_function	sulfonylurea receptor activity
D	0016020	cellular_component	membrane
D	0016887	molecular_function	ATP hydrolysis activity
D	0032991	cellular_component	protein-containing complex
D	0042626	molecular_function	ATPase-coupled transmembrane transporter activity
D	0055085	biological_process	transmembrane transport
D	0071805	biological_process	potassium ion transmembrane transport
D	0140359	molecular_function	ABC-type transporter activity
E	0001508	biological_process	action potential
E	0001666	biological_process	response to hypoxia
E	0001669	cellular_component	acrosomal vesicle
E	0002931	biological_process	response to ischemia
E	0003229	biological_process	ventricular cardiac muscle tissue development
E	0005242	molecular_function	inward rectifier potassium channel activity
E	0005249	molecular_function	voltage-gated potassium channel activity
E	0005515	molecular_function	protein binding
E	0005524	molecular_function	ATP binding
E	0005635	cellular_component	nuclear envelope
E	0005737	cellular_component	cytoplasm
E	0005768	cellular_component	endosome
E	0005886	cellular_component	plasma membrane
E	0006006	biological_process	glucose metabolic process
E	0006813	biological_process	potassium ion transport
E	0006915	biological_process	apoptotic process
E	0006950	biological_process	response to stress
E	0008282	cellular_component	inward rectifying potassium channel
E	0008340	biological_process	determination of adult lifespan
E	0009410	biological_process	response to xenobiotic stimulus
E	0014704	cellular_component	intercalated disc
E	0015272	molecular_function	ATP-activated inward rectifier potassium channel activity
E	0016020	cellular_component	membrane
E	0019829	molecular_function	ATPase-coupled monoatomic cation transmembrane transporter activity
E	0030315	cellular_component	T-tubule
E	0030506	molecular_function	ankyrin binding
E	0030673	cellular_component	axolemma
E	0030955	molecular_function	potassium ion binding
E	0031072	molecular_function	heat shock protein binding
E	0031669	biological_process	cellular response to nutrient levels
E	0032355	biological_process	response to estradiol
E	0033198	biological_process	response to ATP
E	0033574	biological_process	response to testosterone
E	0034220	biological_process	monoatomic ion transmembrane transport
E	0034702	cellular_component	monoatomic ion channel complex
E	0042383	cellular_component	sarcolemma
E	0042391	biological_process	regulation of membrane potential
E	0042734	cellular_component	presynaptic membrane
E	0043025	cellular_component	neuronal cell body
E	0044325	molecular_function	transmembrane transporter binding
E	0046676	biological_process	negative regulation of insulin secretion
E	0050796	biological_process	regulation of insulin secretion
E	0050877	biological_process	nervous system process
E	0061762	biological_process	CAMKK-AMPK signaling cascade
E	0070852	cellular_component	cell body fiber
E	0071316	biological_process	cellular response to nicotine
E	0071333	biological_process	cellular response to glucose stimulus
E	0071356	biological_process	cellular response to tumor necrosis factor
E	0071805	biological_process	potassium ion transmembrane transport
E	0098662	biological_process	inorganic cation transmembrane transport
E	0098978	cellular_component	glutamatergic synapse
E	0099505	biological_process	regulation of presynaptic membrane potential
E	0099508	molecular_function	voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential
E	1903078	biological_process	positive regulation of protein localization to plasma membrane
E	1904638	biological_process	response to resveratrol
E	1990573	biological_process	potassium ion import across plasma membrane
F	0005267	molecular_function	potassium channel activity
F	0005524	molecular_function	ATP binding
F	0005886	cellular_component	plasma membrane
F	0006813	biological_process	potassium ion transport
F	0008281	molecular_function	sulfonylurea receptor activity
F	0016020	cellular_component	membrane
F	0016887	molecular_function	ATP hydrolysis activity
F	0032991	cellular_component	protein-containing complex
F	0042626	molecular_function	ATPase-coupled transmembrane transporter activity
F	0055085	biological_process	transmembrane transport
F	0071805	biological_process	potassium ion transmembrane transport
F	0140359	molecular_function	ABC-type transporter activity
G	0001508	biological_process	action potential
G	0001666	biological_process	response to hypoxia
G	0001669	cellular_component	acrosomal vesicle
G	0002931	biological_process	response to ischemia
G	0003229	biological_process	ventricular cardiac muscle tissue development
G	0005242	molecular_function	inward rectifier potassium channel activity
G	0005249	molecular_function	voltage-gated potassium channel activity
G	0005515	molecular_function	protein binding
G	0005524	molecular_function	ATP binding
G	0005635	cellular_component	nuclear envelope
G	0005737	cellular_component	cytoplasm
G	0005768	cellular_component	endosome
G	0005886	cellular_component	plasma membrane
G	0006006	biological_process	glucose metabolic process
G	0006813	biological_process	potassium ion transport
G	0006915	biological_process	apoptotic process
G	0006950	biological_process	response to stress
G	0008282	cellular_component	inward rectifying potassium channel
G	0008340	biological_process	determination of adult lifespan
G	0009410	biological_process	response to xenobiotic stimulus
G	0014704	cellular_component	intercalated disc
G	0015272	molecular_function	ATP-activated inward rectifier potassium channel activity
G	0016020	cellular_component	membrane
G	0019829	molecular_function	ATPase-coupled monoatomic cation transmembrane transporter activity
G	0030315	cellular_component	T-tubule
G	0030506	molecular_function	ankyrin binding
G	0030673	cellular_component	axolemma
G	0030955	molecular_function	potassium ion binding
G	0031072	molecular_function	heat shock protein binding
G	0031669	biological_process	cellular response to nutrient levels
G	0032355	biological_process	response to estradiol
G	0033198	biological_process	response to ATP
G	0033574	biological_process	response to testosterone
G	0034220	biological_process	monoatomic ion transmembrane transport
G	0034702	cellular_component	monoatomic ion channel complex
G	0042383	cellular_component	sarcolemma
G	0042391	biological_process	regulation of membrane potential
G	0042734	cellular_component	presynaptic membrane
G	0043025	cellular_component	neuronal cell body
G	0044325	molecular_function	transmembrane transporter binding
G	0046676	biological_process	negative regulation of insulin secretion
G	0050796	biological_process	regulation of insulin secretion
G	0050877	biological_process	nervous system process
G	0061762	biological_process	CAMKK-AMPK signaling cascade
G	0070852	cellular_component	cell body fiber
G	0071316	biological_process	cellular response to nicotine
G	0071333	biological_process	cellular response to glucose stimulus
G	0071356	biological_process	cellular response to tumor necrosis factor
G	0071805	biological_process	potassium ion transmembrane transport
G	0098662	biological_process	inorganic cation transmembrane transport
G	0098978	cellular_component	glutamatergic synapse
G	0099505	biological_process	regulation of presynaptic membrane potential
G	0099508	molecular_function	voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential
G	1903078	biological_process	positive regulation of protein localization to plasma membrane
G	1904638	biological_process	response to resveratrol
G	1990573	biological_process	potassium ion import across plasma membrane
H	0005267	molecular_function	potassium channel activity
H	0005524	molecular_function	ATP binding
H	0005886	cellular_component	plasma membrane
H	0006813	biological_process	potassium ion transport
H	0008281	molecular_function	sulfonylurea receptor activity
H	0016020	cellular_component	membrane
H	0016887	molecular_function	ATP hydrolysis activity
H	0032991	cellular_component	protein-containing complex
H	0042626	molecular_function	ATPase-coupled transmembrane transporter activity
H	0055085	biological_process	transmembrane transport
H	0071805	biological_process	potassium ion transmembrane transport
H	0140359	molecular_function	ABC-type transporter activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	binding site for residue ADP A 401

Chain	Residue
A	ILE182
A	LYS185
A	TYR330
A	PHE333
A	GLY334
G	ASN48
G	ARG50

---

site_id	AC2
Number of Residues	10
Details	binding site for residue ADP B 2501

Chain	Residue
B	GLY718
B	LYS719
B	SER720
B	SER721
B	GLN775
B	GLU1480
B	SER1483
B	MG2503
B	TRP688
B	GLY716

---

site_id	AC3
Number of Residues	10
Details	binding site for residue ADP B 2502

Chain	Residue
B	ARG1111
B	GLU1114
B	TYR1354
B	GLY1382
B	SER1383
B	GLY1384
B	LYS1385
B	SER1386
B	SER1387
B	MG2504

---

site_id	AC4
Number of Residues	3
Details	binding site for residue MG B 2503

Chain	Residue
B	SER720
B	GLN775
B	ADP2501

---

site_id	AC5
Number of Residues	3
Details	binding site for residue MG B 2504

Chain	Residue
B	SER1386
B	GLN1427
B	ADP2502

---

site_id	AC6
Number of Residues	7
Details	binding site for residue ADP C 401

Chain	Residue
A	ASN48
A	ARG50
C	ILE182
C	LYS185
C	TYR330
C	PHE333
C	GLY334

---

site_id	AC7
Number of Residues	10
Details	binding site for residue ADP D 2501

Chain	Residue
D	TRP688
D	GLY716
D	GLY718
D	LYS719
D	SER720
D	SER721
D	GLN775
D	GLU1480
D	SER1483
D	MG2503

---

site_id	AC8
Number of Residues	10
Details	binding site for residue ADP D 2502

Chain	Residue
D	ARG1111
D	GLU1114
D	TYR1354
D	GLY1382
D	SER1383
D	GLY1384
D	LYS1385
D	SER1386
D	SER1387
D	MG2504

---

site_id	AC9
Number of Residues	3
Details	binding site for residue MG D 2503

Chain	Residue
D	SER720
D	GLN775
D	ADP2501

---

site_id	AD1
Number of Residues	3
Details	binding site for residue MG D 2504

Chain	Residue
D	SER1386
D	GLN1427
D	ADP2502

---

site_id	AD2
Number of Residues	7
Details	binding site for residue ADP E 401

Chain	Residue
C	ASN48
C	ARG50
E	ILE182
E	LYS185
E	TYR330
E	PHE333
E	GLY334

---

site_id	AD3
Number of Residues	10
Details	binding site for residue ADP F 2501

Chain	Residue
F	TRP688
F	GLY716
F	GLY718
F	LYS719
F	SER720
F	SER721
F	GLN775
F	GLU1480
F	SER1483
F	MG2503

---

site_id	AD4
Number of Residues	10
Details	binding site for residue ADP F 2502

Chain	Residue
F	ARG1111
F	GLU1114
F	TYR1354
F	GLY1382
F	SER1383
F	GLY1384
F	LYS1385
F	SER1386
F	SER1387
F	MG2504

---

site_id	AD5
Number of Residues	3
Details	binding site for residue MG F 2503

Chain	Residue
F	SER720
F	GLN775
F	ADP2501

---

site_id	AD6
Number of Residues	3
Details	binding site for residue MG F 2504

Chain	Residue
F	SER1386
F	GLN1427
F	ADP2502

---

site_id	AD7
Number of Residues	7
Details	binding site for residue ADP G 401

Chain	Residue
E	ASN48
E	ARG50
G	ILE182
G	LYS185
G	TYR330
G	PHE333
G	GLY334

---

site_id	AD8
Number of Residues	10
Details	binding site for residue ADP H 2501

Chain	Residue
H	TRP688
H	GLY716
H	GLY718
H	LYS719
H	SER720
H	SER721
H	GLN775
H	GLU1480
H	SER1483
H	MG2503

---

site_id	AD9
Number of Residues	10
Details	binding site for residue ADP H 2502

Chain	Residue
H	ARG1111
H	GLU1114
H	TYR1354
H	GLY1382
H	SER1383
H	GLY1384
H	LYS1385
H	SER1386
H	SER1387
H	MG2504

---

site_id	AE1
Number of Residues	3
Details	binding site for residue MG H 2503

Chain	Residue
H	SER720
H	GLN775
H	ADP2501

---

site_id	AE2
Number of Residues	3
Details	binding site for residue MG H 2504

Chain	Residue
H	SER1386
H	GLN1427
H	ADP2502

---

Functional Information from PROSITE/UniProt

site_id	PS00211
Number of Residues	15
Details	ABC_TRANSPORTER_1 ABC transporters family signature. LSGGQRQRISVARAL

Chain	Residue	Details
B	LEU830-LEU844
B	PHE1482-PHE1496

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	392
Details	TOPO_DOM: Extracellular => ECO:0000269|PubMed:10506167

Chain	Residue	Details
B	MET1-VAL34
D	ARG1274-SER1277
F	MET1-VAL34
F	GLY97-SER101
F	VAL155-LEU167
F	LEU1027-SER1073
F	ARG1274-SER1277
H	MET1-VAL34
H	GLY97-SER101
H	VAL155-LEU167
H	LEU1027-SER1073
B	GLY97-SER101
H	ARG1274-SER1277
B	VAL155-LEU167
B	LEU1027-SER1073
B	ARG1274-SER1277
D	MET1-VAL34
D	GLY97-SER101
D	VAL155-LEU167
D	LEU1027-SER1073

---

site_id	SWS_FT_FI2
Number of Residues	80
Details	TRANSMEM: Helical; Name=1

Chain	Residue	Details
B	PRO35-SER55
D	PRO35-SER55
F	PRO35-SER55
H	PRO35-SER55

---

site_id	SWS_FT_FI3
Number of Residues	3312
Details	TOPO_DOM: Cytoplasmic => ECO:0000269|PubMed:10506167

Chain	Residue	Details
B	SER56-TRP75
D	VAL1299-LYS1582
F	SER56-TRP75
F	TYR123-LYS134
F	TYR195-LEU311
F	SER606-LEU1005
F	VAL1299-LYS1582
H	SER56-TRP75
H	TYR123-LYS134
H	TYR195-LEU311
H	SER606-LEU1005
B	TYR123-LYS134
H	VAL1299-LYS1582
B	TYR195-LEU311
B	SER606-LEU1005
B	VAL1299-LYS1582
D	SER56-TRP75
D	TYR123-LYS134
D	TYR195-LEU311
D	SER606-LEU1005

---

site_id	SWS_FT_FI4
Number of Residues	80
Details	TRANSMEM: Helical; Name=2

Chain	Residue	Details
B	ILE76-ASP96
D	ILE76-ASP96
F	ILE76-ASP96
H	ILE76-ASP96

---

site_id	SWS_FT_FI5
Number of Residues	80
Details	TRANSMEM: Helical; Name=3

Chain	Residue	Details
B	ARG102-VAL122
D	ARG102-VAL122
F	ARG102-VAL122
H	ARG102-VAL122

---

site_id	SWS_FT_FI6
Number of Residues	76
Details	TRANSMEM: Helical; Name=4

Chain	Residue	Details
B	LEU135-PHE154
D	LEU135-PHE154
F	LEU135-PHE154
H	LEU135-PHE154

---

site_id	SWS_FT_FI7
Number of Residues	104
Details	TRANSMEM: Helical; Name=5

Chain	Residue	Details
B	ARG168-ARG194
D	ARG168-ARG194
F	ARG168-ARG194
H	ARG168-ARG194

---

site_id	SWS_FT_FI8
Number of Residues	76
Details	TRANSMEM: Helical; Name=6 => ECO:0000255|PROSITE-ProRule:PRU00441

Chain	Residue	Details
B	LEU312-ASN331
D	LEU312-ASN331
F	LEU312-ASN331
H	LEU312-ASN331

---

site_id	SWS_FT_FI9
Number of Residues	188
Details	TOPO_DOM: Extracellular => ECO:0000250

Chain	Residue	Details
B	HIS332-ALA355
F	LEU456-VAL458
F	VAL563-HIS584
F	VAL1160
H	HIS332-ALA355
H	LEU456-VAL458
H	VAL563-HIS584
H	VAL1160
B	LEU456-VAL458
B	VAL563-HIS584
B	VAL1160
D	HIS332-ALA355
D	LEU456-VAL458
D	VAL563-HIS584
D	VAL1160
F	HIS332-ALA355

---

site_id	SWS_FT_FI10
Number of Residues	80
Details	TRANSMEM: Helical; Name=7 => ECO:0000255|PROSITE-ProRule:PRU00441

Chain	Residue	Details
B	TYR356-SER376
D	TYR356-SER376
F	TYR356-SER376
H	TYR356-SER376

---

site_id	SWS_FT_FI11
Number of Residues	924
Details	TOPO_DOM: Cytoplasmic => ECO:0000250

Chain	Residue	Details
B	TYR377-LEU434
F	LYS480-SER541
F	LYS1095-SER1138
F	PHE1182-MET1252
H	TYR377-LEU434
H	LYS480-SER541
H	LYS1095-SER1138
H	PHE1182-MET1252
B	LYS480-SER541
B	LYS1095-SER1138
B	PHE1182-MET1252
D	TYR377-LEU434
D	LYS480-SER541
D	LYS1095-SER1138
D	PHE1182-MET1252
F	TYR377-LEU434

---

site_id	SWS_FT_FI12
Number of Residues	80
Details	TRANSMEM: Helical; Name=8 => ECO:0000255|PROSITE-ProRule:PRU00441

Chain	Residue	Details
B	CYS435-ILE455
D	CYS435-ILE455
F	CYS435-ILE455
H	CYS435-ILE455

---

site_id	SWS_FT_FI13
Number of Residues	80
Details	TRANSMEM: Helical; Name=9 => ECO:0000255|PROSITE-ProRule:PRU00441

Chain	Residue	Details
B	SER459-THR479
D	SER459-THR479
F	SER459-THR479
H	SER459-THR479

---

site_id	SWS_FT_FI14
Number of Residues	80
Details	TRANSMEM: Helical; Name=10 => ECO:0000255|PROSITE-ProRule:PRU00441

Chain	Residue	Details
B	ILE542-HIS562
D	ILE542-HIS562
F	ILE542-HIS562
H	ILE542-HIS562

---

site_id	SWS_FT_FI15
Number of Residues	80
Details	TRANSMEM: Helical; Name=11 => ECO:0000255|PROSITE-ProRule:PRU00441

Chain	Residue	Details
B	ILE585-VAL605
D	ILE585-VAL605
F	ILE585-VAL605
H	ILE585-VAL605

---

site_id	SWS_FT_FI16
Number of Residues	80
Details	TRANSMEM: Helical; Name=12

Chain	Residue	Details
B	SER1006-VAL1026
D	SER1006-VAL1026
F	SER1006-VAL1026
H	SER1006-VAL1026

---

site_id	SWS_FT_FI17
Number of Residues	80
Details	TRANSMEM: Helical; Name=13 => ECO:0000255|PROSITE-ProRule:PRU00441

Chain	Residue	Details
B	LEU1074-ALA1094
D	LEU1074-ALA1094
F	LEU1074-ALA1094
H	LEU1074-ALA1094

---

site_id	SWS_FT_FI18
Number of Residues	80
Details	TRANSMEM: Helical; Name=14 => ECO:0000255|PROSITE-ProRule:PRU00441

Chain	Residue	Details
B	THR1139-TYR1159
D	THR1139-TYR1159
F	THR1139-TYR1159
H	THR1139-TYR1159

---

site_id	SWS_FT_FI19
Number of Residues	80
Details	TRANSMEM: Helical; Name=15 => ECO:0000255|PROSITE-ProRule:PRU00441

Chain	Residue	Details
B	THR1161-TYR1181
D	THR1161-TYR1181
F	THR1161-TYR1181
H	THR1161-TYR1181

---

site_id	SWS_FT_FI20
Number of Residues	80
Details	TRANSMEM: Helical; Name=16 => ECO:0000255|PROSITE-ProRule:PRU00441

Chain	Residue	Details
B	GLU1253-HIS1273
D	GLU1253-HIS1273
F	GLU1253-HIS1273
H	GLU1253-HIS1273

---

site_id	SWS_FT_FI21
Number of Residues	80
Details	TRANSMEM: Helical; Name=17

Chain	Residue	Details
B	ALA1278-MET1298
D	ALA1278-MET1298
F	ALA1278-MET1298
H	ALA1278-MET1298

---

site_id	SWS_FT_FI22
Number of Residues	8
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00434

Chain	Residue	Details
B	GLY713
B	GLY1379
D	GLY713
D	GLY1379
F	GLY713
F	GLY1379
H	GLY713
H	GLY1379

---

site_id	SWS_FT_FI23
Number of Residues	4
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:10506167, ECO:0000269|PubMed:8942641

Chain	Residue	Details
B	ASN10
D	ASN10
F	ASN10
H	ASN10

---

site_id	SWS_FT_FI24
Number of Residues	4
Details	CARBOHYD: N-linked (GlcNAc...) asparagine

Chain	Residue	Details
B	ASN1050
D	ASN1050
F	ASN1050
H	ASN1050

---