5YW5

Crystal structure of Adenine phosphoribosyltransferase from Francisella tularensis in complex with adenine

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0002055	molecular_function	adenine binding
A	0003999	molecular_function	adenine phosphoribosyltransferase activity
A	0005737	cellular_component	cytoplasm
A	0006166	biological_process	purine ribonucleoside salvage
A	0006168	biological_process	adenine salvage
A	0009116	biological_process	nucleoside metabolic process
A	0016208	molecular_function	AMP binding
A	0016757	molecular_function	glycosyltransferase activity
A	0044209	biological_process	AMP salvage
B	0002055	molecular_function	adenine binding
B	0003999	molecular_function	adenine phosphoribosyltransferase activity
B	0005737	cellular_component	cytoplasm
B	0006166	biological_process	purine ribonucleoside salvage
B	0006168	biological_process	adenine salvage
B	0009116	biological_process	nucleoside metabolic process
B	0016208	molecular_function	AMP binding
B	0016757	molecular_function	glycosyltransferase activity
B	0044209	biological_process	AMP salvage
C	0002055	molecular_function	adenine binding
C	0003999	molecular_function	adenine phosphoribosyltransferase activity
C	0005737	cellular_component	cytoplasm
C	0006166	biological_process	purine ribonucleoside salvage
C	0006168	biological_process	adenine salvage
C	0009116	biological_process	nucleoside metabolic process
C	0016208	molecular_function	AMP binding
C	0016757	molecular_function	glycosyltransferase activity
C	0044209	biological_process	AMP salvage
D	0002055	molecular_function	adenine binding
D	0003999	molecular_function	adenine phosphoribosyltransferase activity
D	0005737	cellular_component	cytoplasm
D	0006166	biological_process	purine ribonucleoside salvage
D	0006168	biological_process	adenine salvage
D	0009116	biological_process	nucleoside metabolic process
D	0016208	molecular_function	AMP binding
D	0016757	molecular_function	glycosyltransferase activity
D	0044209	biological_process	AMP salvage

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue ADE A 201

Chain	Residue
A	MET22
A	PHE23
A	ARG24
A	LEU155

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site_id	AC2
Number of Residues	3
Details	binding site for residue ADE B 201

Chain	Residue
B	MET22
B	PHE23
B	ARG24

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site_id	AC3
Number of Residues	4
Details	binding site for residue ADE C 201

Chain	Residue
C	ARG24
C	LEU125
C	MET22
C	PHE23

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site_id	AC4
Number of Residues	4
Details	binding site for residue ADE D 201

Chain	Residue
D	MET22
D	PHE23
D	ARG24
D	LEU125

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Functional Information from PROSITE/UniProt

site_id	PS00103
Number of Residues	13
Details	PUR_PYR_PR_TRANSFER Purine/pyrimidine phosphoribosyl transferases signature. VLVVDDLLATGgT

Chain	Residue	Details
A	VAL119-THR131

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