5YW2
Crystal structure of Adenine phosphoribosyltransferase from Francisella tularensis.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0002055 | molecular_function | adenine binding |
| A | 0003999 | molecular_function | adenine phosphoribosyltransferase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006166 | biological_process | purine ribonucleoside salvage |
| A | 0006168 | biological_process | adenine salvage |
| A | 0009116 | biological_process | nucleoside metabolic process |
| A | 0016208 | molecular_function | AMP binding |
| A | 0016757 | molecular_function | glycosyltransferase activity |
| A | 0044209 | biological_process | AMP salvage |
| B | 0002055 | molecular_function | adenine binding |
| B | 0003999 | molecular_function | adenine phosphoribosyltransferase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006166 | biological_process | purine ribonucleoside salvage |
| B | 0006168 | biological_process | adenine salvage |
| B | 0009116 | biological_process | nucleoside metabolic process |
| B | 0016208 | molecular_function | AMP binding |
| B | 0016757 | molecular_function | glycosyltransferase activity |
| B | 0044209 | biological_process | AMP salvage |
| C | 0002055 | molecular_function | adenine binding |
| C | 0003999 | molecular_function | adenine phosphoribosyltransferase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0006166 | biological_process | purine ribonucleoside salvage |
| C | 0006168 | biological_process | adenine salvage |
| C | 0009116 | biological_process | nucleoside metabolic process |
| C | 0016208 | molecular_function | AMP binding |
| C | 0016757 | molecular_function | glycosyltransferase activity |
| C | 0044209 | biological_process | AMP salvage |
| D | 0002055 | molecular_function | adenine binding |
| D | 0003999 | molecular_function | adenine phosphoribosyltransferase activity |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0006166 | biological_process | purine ribonucleoside salvage |
| D | 0006168 | biological_process | adenine salvage |
| D | 0009116 | biological_process | nucleoside metabolic process |
| D | 0016208 | molecular_function | AMP binding |
| D | 0016757 | molecular_function | glycosyltransferase activity |
| D | 0044209 | biological_process | AMP salvage |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | binding site for residue SO4 A 201 |
| Chain | Residue |
| A | LEU125 |
| A | LEU126 |
| A | ALA127 |
| A | THR128 |
| A | GLY129 |
| A | GLY130 |
| A | THR131 |
| A | ALA132 |
| A | HOH303 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue MG A 202 |
| Chain | Residue |
| A | HOH301 |
| A | HOH308 |
| A | HOH320 |
| A | HOH321 |
| A | HOH322 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 203 |
| Chain | Residue |
| A | SER62 |
| A | ARG63 |
| B | ARG83 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue CL A 204 |
| Chain | Residue |
| A | ARG83 |
| B | ARG63 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 205 |
| Chain | Residue |
| A | ARG83 |
| B | SER62 |
| B | ARG63 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 206 |
| Chain | Residue |
| A | ARG63 |
| A | HOH304 |
| B | ARG83 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 C 201 |
| Chain | Residue |
| C | LEU125 |
| C | LEU126 |
| C | ALA127 |
| C | THR128 |
| C | GLY129 |
| C | GLY130 |
| C | THR131 |
| C | ALA132 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | binding site for residue CL C 202 |
| Chain | Residue |
| C | SER62 |
| D | ARG83 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | binding site for residue CL C 203 |
| Chain | Residue |
| C | ARG63 |
| D | ARG83 |
| site_id | AD1 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 B 201 |
| Chain | Residue |
| B | LEU125 |
| B | LEU126 |
| B | ALA127 |
| B | THR128 |
| B | GLY129 |
| B | GLY130 |
| B | THR131 |
| B | ALA132 |
| site_id | AD2 |
| Number of Residues | 2 |
| Details | binding site for residue CL D 201 |
| Chain | Residue |
| C | ARG83 |
| D | ARG63 |
| site_id | AD3 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 D 202 |
| Chain | Residue |
| D | LEU125 |
| D | ALA127 |
| D | THR128 |
| D | GLY129 |
| D | GLY130 |
| D | THR131 |
| D | ALA132 |
| D | HOH301 |
| site_id | AD4 |
| Number of Residues | 5 |
| Details | binding site for residue MG D 203 |
| Chain | Residue |
| D | HOH302 |
| D | HOH303 |
| D | HOH310 |
| D | HOH311 |
| D | HOH313 |
| site_id | AD5 |
| Number of Residues | 3 |
| Details | binding site for residue CL D 204 |
| Chain | Residue |
| C | ARG83 |
| D | SER62 |
| D | ARG63 |
Functional Information from PROSITE/UniProt
| site_id | PS00103 |
| Number of Residues | 13 |
| Details | PUR_PYR_PR_TRANSFER Purine/pyrimidine phosphoribosyl transferases signature. VLVVDDLLATGgT |
| Chain | Residue | Details |
| A | VAL119-THR131 |
