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5YVR

Crystal Structure of the H277A mutant of ADH/D1, an archaeal halo-thermophilic Red Sea brine pool alcohol dehydrogenase

Functional Information from GO Data
ChainGOidnamespacecontents
A0000166molecular_functionnucleotide binding
A0004022molecular_functionalcohol dehydrogenase (NAD+) activity
A0016491molecular_functionoxidoreductase activity
A0016616molecular_functionoxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
A0046872molecular_functionmetal ion binding
Functional Information from PDB Data
site_idAC1
Number of Residues6
Detailsbinding site for residue MN A 501
ChainResidue
AASP204
AHIS208
AHIS273
AHIS288
ALEU292
ANDP502

site_idAC2
Number of Residues37
Detailsbinding site for residue NDP A 502
ChainResidue
AASN41
AASN71
AGLY97
AGLY98
ASER99
AASP102
ASER148
ATHR149
ATHR152
ASER154
ATHR157
ATYR159
AVAL161
ALYS170
AILE189
AGLU192
AMET193
APRO194
ALEU197
ATHR201
AASP204
AHIS208
AHIS288
AMN501
AHOH617
AHOH624
AHOH627
AHOH628
AHOH631
AHOH636
AHOH638
AHOH651
AHOH661
AHOH667
AGLY38
ALYS39
ASER40

Functional Information from PROSITE/UniProt
site_idPS00913
Number of Residues29
DetailsADH_IRON_1 Iron-containing alcohol dehydrogenases signature 1. SIvDidilkemPprltAiTgyDVFshvsE
ChainResidueDetails
ASER183-GLU211

238582

PDB entries from 2025-07-09

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