5YUA
Crystal structure of voltage-gated sodium channel NavAb in high-pH condition
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0001518 | cellular_component | voltage-gated sodium channel complex |
| A | 0005216 | molecular_function | monoatomic ion channel activity |
| A | 0005248 | molecular_function | voltage-gated sodium channel activity |
| A | 0005261 | molecular_function | monoatomic cation channel activity |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006811 | biological_process | monoatomic ion transport |
| A | 0016020 | cellular_component | membrane |
| A | 0034220 | biological_process | monoatomic ion transmembrane transport |
| A | 0035725 | biological_process | sodium ion transmembrane transport |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0055085 | biological_process | transmembrane transport |
| A | 0098655 | biological_process | monoatomic cation transmembrane transport |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue LMT A 1303 |
| Chain | Residue |
| A | ILE1097 |
| A | LEU1151 |
| A | TYR1191 |
| A | TYR1193 |
| A | VAL1196 |
| A | PX41308 |
| A | PX41309 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue 1N7 A 1304 |
| Chain | Residue |
| A | LEU1131 |
| A | SER1132 |
| A | PX41310 |
| A | GLN1115 |
| A | PRO1128 |
| site_id | AC3 |
| Number of Residues | 11 |
| Details | binding site for residue PX4 A 1305 |
| Chain | Residue |
| A | PHE1141 |
| A | GLY1164 |
| A | GLU1165 |
| A | PHE1167 |
| A | MET1188 |
| A | PRO1192 |
| A | TRP1195 |
| A | PHE1203 |
| A | LMT1302 |
| A | PX41306 |
| A | PX41309 |
| site_id | AC4 |
| Number of Residues | 11 |
| Details | binding site for residue PX4 A 1306 |
| Chain | Residue |
| A | GLY1026 |
| A | ILE1027 |
| A | GLY1030 |
| A | SER1034 |
| A | THR1036 |
| A | LEU1139 |
| A | TYR1142 |
| A | THR1162 |
| A | LEU1163 |
| A | GLY1164 |
| A | PX41305 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue PX4 A 1308 |
| Chain | Residue |
| A | PRO1075 |
| A | TRP1076 |
| A | LMT1303 |
| A | PX41307 |
| A | PX41310 |
| site_id | AC6 |
| Number of Residues | 25 |
| Details | binding site for Poly-Saccharide residues LMT A 1302 through PX4 A 1307 |
| Chain | Residue |
| A | TRP1076 |
| A | PHE1079 |
| A | SER1121 |
| A | ILE1124 |
| A | ILE1127 |
| A | PRO1128 |
| A | LEU1136 |
| A | MET1174 |
| A | THR1175 |
| A | LEU1176 |
| A | LEU1176 |
| A | THR1206 |
| A | THR1206 |
| A | MET1209 |
| A | PX41305 |
| A | PX41308 |
| A | PX41310 |
| A | HOH1401 |
| A | HOH1401 |
| A | HOH1401 |
| A | HOH1401 |
| A | HOH1403 |
| A | HOH1403 |
| A | HOH1403 |
| A | HOH1403 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | binding site for residues PX4 A 1309 and PX4 A 1310 |
| Chain | Residue |
| A | ILE1097 |
| A | LEU1131 |
| A | TYR1193 |
| A | LMT1303 |
| A | 1N71304 |
| A | PX41305 |
| A | PX41307 |
| A | PX41308 |
