5YU7
CRYSTAL STRUCTURE OF EXPORTIN-5
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000049 | molecular_function | tRNA binding |
| A | 0003723 | molecular_function | RNA binding |
| A | 0003729 | molecular_function | mRNA binding |
| A | 0005049 | molecular_function | nuclear export signal receptor activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005654 | cellular_component | nucleoplasm |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006405 | biological_process | RNA export from nucleus |
| A | 0006611 | biological_process | protein export from nucleus |
| A | 0006886 | biological_process | intracellular protein transport |
| A | 0010586 | biological_process | miRNA metabolic process |
| A | 0015031 | biological_process | protein transport |
| A | 0016442 | cellular_component | RISC complex |
| A | 0031047 | biological_process | regulatory ncRNA-mediated gene silencing |
| A | 0031267 | molecular_function | small GTPase binding |
| A | 0035281 | biological_process | pre-miRNA export from nucleus |
| A | 0042565 | cellular_component | RNA nuclear export complex |
| A | 0070883 | molecular_function | pre-miRNA binding |
| A | 1905172 | molecular_function | RISC complex binding |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 107 |
| Details | Region: {"description":"Necessary for interaction with ILF3"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Region: {"description":"Pre-miRNA binding","evidences":[{"source":"PubMed","id":"19965479","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Site: {"description":"Pre-miRNA binding","evidences":[{"source":"PubMed","id":"19965479","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18691976","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
