5YSR

Ethanolamine ammonia-lyase, AdoCbl/2-amino-1-propanol

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005829	cellular_component	cytosol
A	0006520	biological_process	amino acid metabolic process
A	0008851	molecular_function	ethanolamine ammonia-lyase activity
A	0009350	cellular_component	ethanolamine ammonia-lyase complex
A	0016829	molecular_function	lyase activity
A	0031419	molecular_function	cobalamin binding
A	0031469	cellular_component	bacterial microcompartment
A	0031471	cellular_component	ethanolamine degradation polyhedral organelle
A	0046336	biological_process	ethanolamine catabolic process
B	0006520	biological_process	amino acid metabolic process
B	0008851	molecular_function	ethanolamine ammonia-lyase activity
B	0009350	cellular_component	ethanolamine ammonia-lyase complex
B	0016829	molecular_function	lyase activity
B	0031419	molecular_function	cobalamin binding
B	0031469	cellular_component	bacterial microcompartment
B	0031471	cellular_component	ethanolamine degradation polyhedral organelle
B	0046336	biological_process	ethanolamine catabolic process
C	0005829	cellular_component	cytosol
C	0006520	biological_process	amino acid metabolic process
C	0008851	molecular_function	ethanolamine ammonia-lyase activity
C	0009350	cellular_component	ethanolamine ammonia-lyase complex
C	0016829	molecular_function	lyase activity
C	0031419	molecular_function	cobalamin binding
C	0031469	cellular_component	bacterial microcompartment
C	0031471	cellular_component	ethanolamine degradation polyhedral organelle
C	0046336	biological_process	ethanolamine catabolic process
D	0006520	biological_process	amino acid metabolic process
D	0008851	molecular_function	ethanolamine ammonia-lyase activity
D	0009350	cellular_component	ethanolamine ammonia-lyase complex
D	0016829	molecular_function	lyase activity
D	0031419	molecular_function	cobalamin binding
D	0031469	cellular_component	bacterial microcompartment
D	0031471	cellular_component	ethanolamine degradation polyhedral organelle
D	0046336	biological_process	ethanolamine catabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	binding site for residue 5AD A 501

Chain	Residue
A	ASN193
B	B12601
A	SER247
A	ILE248
A	GLU287
A	THR288
A	GLY289
A	SER292
A	VAL326
A	PHE329

---

site_id	AC2
Number of Residues	8
Details	binding site for residue GOL A 502

Chain	Residue
A	ILE76
A	ARG114
A	LEU117
A	THR118
A	SER119
A	GLY313
A	SER355
A	GOL504

---

site_id	AC3
Number of Residues	4
Details	binding site for residue GOL A 503

Chain	Residue
A	LYS145
A	ARG316
A	GLY356
A	HOH748

---

site_id	AC4
Number of Residues	7
Details	binding site for residue GOL A 504

Chain	Residue
A	ASP79
A	ARG316
A	GOL502
A	HOH627
C	GLU281
C	HOH675
C	HOH777

---

site_id	AC5
Number of Residues	10
Details	binding site for residue GOL A 505

Chain	Residue
A	GLY272
A	ALA273
A	ILE278
A	GLY280
A	GLU281
A	ASN282
A	CYS283
A	HOH606
A	HOH625
C	LYS115

---

site_id	AC6
Number of Residues	3
Details	binding site for residue GOL A 506

Chain	Residue
A	LYS139
A	PRO154
A	GLY155

---

site_id	AC7
Number of Residues	2
Details	binding site for residue GOL A 507

Chain	Residue
A	PRO142
A	PRO154

---

site_id	AC8
Number of Residues	35
Details	binding site for residue B12 B 601

Chain	Residue
A	ASN193
A	PRO194
A	VAL195
A	THR196
A	LEU225
A	ALA226
A	HIS227
A	PHE245
A	GLN246
A	SER247
A	GLU257
A	PHE258
A	SER295
A	PHE329
A	ILE330
A	MET401
A	LEU402
A	5AD501
A	HOH665
B	ARG141
B	LEU169
B	ARG206
B	VAL207
B	LYS208
B	GLU228
B	ARG229
B	TYR241
B	GLU253
B	ARG256
B	CYS258
B	SER260
B	ASN261
B	HOH711
B	HOH712
B	HOH726

---

site_id	AC9
Number of Residues	14
Details	binding site for residue 5AD C 501

Chain	Residue
C	ASN193
C	SER247
C	ILE248
C	GLU287
C	THR288
C	GLY289
C	SER292
C	VAL326
C	PHE329
C	LEU402
C	HOH602
C	HOH640
C	HOH646
D	B12601

---

site_id	AD1
Number of Residues	3
Details	binding site for residue GOL C 502

Chain	Residue
C	LYS145
C	ARG316
C	GLY356

---

site_id	AD2
Number of Residues	4
Details	binding site for residue GOL C 503

Chain	Residue
C	HOH713
C	PRO154
C	GLY155
C	THR156

---

site_id	AD3
Number of Residues	8
Details	binding site for residue GOL C 504

Chain	Residue
A	LYS115
C	ARG269
C	GLY272
C	ALA273
C	GLY280
C	GLU281
C	CYS283
C	HOH675

---

site_id	AD4
Number of Residues	5
Details	binding site for residue GOL C 505

Chain	Residue
C	ASP207
C	THR208
C	GLY211
C	VAL212
C	HOH620

---

site_id	AD5
Number of Residues	3
Details	binding site for residue GOL C 506

Chain	Residue
C	ALA34
C	GLY35
C	HOH744

---

site_id	AD6
Number of Residues	34
Details	binding site for residue B12 D 601

Chain	Residue
C	ASN193
C	PRO194
C	VAL195
C	THR196
C	ASP197
C	LEU225
C	ALA226
C	HIS227
C	PHE245
C	GLN246
C	SER247
C	GLU257
C	PHE258
C	SER295
C	PHE329
C	ILE330
C	MET401
C	LEU402
C	5AD501
D	ARG206
D	VAL207
D	LYS208
D	GLY227
D	GLU228
D	ARG229
D	TYR241
D	GLU253
D	ARG256
D	CYS258
D	SER260
D	ASN261
D	HOH701
D	HOH707
D	HOH720

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00861","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"20519496","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21142024","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3ABO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3ABS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3ANY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3AO0","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00861","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"20519496","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21142024","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3ABO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3ABS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3AO0","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00861","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"29797764","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3ABR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5YSN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5YSR","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00861","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"20519496","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21142024","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3ABO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3ABQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3ANY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3AO0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5YSN","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00861","evidenceCode":"ECO:0000255"},{"evidenceCode":"ECO:0000305"},{"source":"PDB","id":"3ABR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3ANY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3AO0","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00861","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"20519496","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21142024","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3ABO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3ABQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3ANY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3AO0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5YSN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5YSR","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00601","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"20519496","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21142024","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3ABO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3ABQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3ABR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5YSN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5YSR","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00601","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"20519496","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21142024","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3ABO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3ABQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3ABR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3ANY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3AO0","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00601","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"20519496","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21142024","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3ABO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3ABR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3AO0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5YSN","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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