5YSN
Ethanolamine ammonia-lyase, AdoCbl/substrate-free
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005829 | cellular_component | cytosol |
| A | 0006520 | biological_process | amino acid metabolic process |
| A | 0008851 | molecular_function | ethanolamine ammonia-lyase activity |
| A | 0009350 | cellular_component | ethanolamine ammonia-lyase complex |
| A | 0016829 | molecular_function | lyase activity |
| A | 0031419 | molecular_function | cobalamin binding |
| A | 0031469 | cellular_component | bacterial microcompartment |
| A | 0031471 | cellular_component | ethanolamine degradation polyhedral organelle |
| A | 0046336 | biological_process | ethanolamine catabolic process |
| B | 0006520 | biological_process | amino acid metabolic process |
| B | 0008851 | molecular_function | ethanolamine ammonia-lyase activity |
| B | 0009350 | cellular_component | ethanolamine ammonia-lyase complex |
| B | 0016829 | molecular_function | lyase activity |
| B | 0031419 | molecular_function | cobalamin binding |
| B | 0031469 | cellular_component | bacterial microcompartment |
| B | 0031471 | cellular_component | ethanolamine degradation polyhedral organelle |
| B | 0046336 | biological_process | ethanolamine catabolic process |
| C | 0005829 | cellular_component | cytosol |
| C | 0006520 | biological_process | amino acid metabolic process |
| C | 0008851 | molecular_function | ethanolamine ammonia-lyase activity |
| C | 0009350 | cellular_component | ethanolamine ammonia-lyase complex |
| C | 0016829 | molecular_function | lyase activity |
| C | 0031419 | molecular_function | cobalamin binding |
| C | 0031469 | cellular_component | bacterial microcompartment |
| C | 0031471 | cellular_component | ethanolamine degradation polyhedral organelle |
| C | 0046336 | biological_process | ethanolamine catabolic process |
| D | 0006520 | biological_process | amino acid metabolic process |
| D | 0008851 | molecular_function | ethanolamine ammonia-lyase activity |
| D | 0009350 | cellular_component | ethanolamine ammonia-lyase complex |
| D | 0016829 | molecular_function | lyase activity |
| D | 0031419 | molecular_function | cobalamin binding |
| D | 0031469 | cellular_component | bacterial microcompartment |
| D | 0031471 | cellular_component | ethanolamine degradation polyhedral organelle |
| D | 0046336 | biological_process | ethanolamine catabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | binding site for residue 5AD A 501 |
| Chain | Residue |
| A | ASN193 |
| A | HOH713 |
| A | HOH717 |
| B | B12601 |
| A | PHE245 |
| A | SER247 |
| A | GLU287 |
| A | THR288 |
| A | GLY289 |
| A | VAL326 |
| A | PHE329 |
| A | HOH620 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 502 |
| Chain | Residue |
| A | ILE76 |
| A | ARG114 |
| A | LEU117 |
| A | THR118 |
| A | SER119 |
| A | SER355 |
| A | GOL504 |
| A | HOH759 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 503 |
| Chain | Residue |
| A | LYS145 |
| A | ARG316 |
| A | GLY356 |
| A | HOH758 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 504 |
| Chain | Residue |
| A | ASP79 |
| A | ARG316 |
| A | GOL502 |
| A | HOH755 |
| C | GLU281 |
| C | GOL506 |
| C | HOH854 |
| site_id | AC5 |
| Number of Residues | 10 |
| Details | binding site for residue GOL A 505 |
| Chain | Residue |
| A | GLY272 |
| A | ALA273 |
| A | ILE278 |
| A | GLY280 |
| A | GLU281 |
| A | ASN282 |
| A | CYS283 |
| A | HOH607 |
| A | HOH659 |
| C | LYS115 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 506 |
| Chain | Residue |
| A | HIS368 |
| A | ALA369 |
| A | ASP370 |
| B | LYS103 |
| B | LEU134 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | binding site for residue GOL A 507 |
| Chain | Residue |
| A | MET434 |
| A | LEU451 |
| A | HOH798 |
| site_id | AC8 |
| Number of Residues | 37 |
| Details | binding site for residue B12 B 601 |
| Chain | Residue |
| A | ASN193 |
| A | PRO194 |
| A | VAL195 |
| A | ALA226 |
| A | HIS227 |
| A | PHE245 |
| A | GLN246 |
| A | SER247 |
| A | GLU257 |
| A | PHE258 |
| A | SER295 |
| A | PHE329 |
| A | ILE330 |
| A | MET401 |
| A | LEU402 |
| A | ASN403 |
| A | 5AD501 |
| A | HOH631 |
| A | HOH713 |
| B | ARG141 |
| B | ARG206 |
| B | VAL207 |
| B | LYS208 |
| B | GLU228 |
| B | ARG229 |
| B | TYR241 |
| B | GLU253 |
| B | ALA254 |
| B | ARG256 |
| B | CYS258 |
| B | SER260 |
| B | HOH704 |
| B | HOH723 |
| B | HOH733 |
| B | HOH737 |
| B | HOH770 |
| B | HOH777 |
| site_id | AC9 |
| Number of Residues | 12 |
| Details | binding site for residue 5AD C 501 |
| Chain | Residue |
| C | ASN193 |
| C | PHE245 |
| C | SER247 |
| C | GLU287 |
| C | THR288 |
| C | GLY289 |
| C | VAL326 |
| C | PHE329 |
| C | HOH650 |
| C | HOH652 |
| C | HOH679 |
| D | B12601 |
| site_id | AD1 |
| Number of Residues | 5 |
| Details | binding site for residue GOL C 502 |
| Chain | Residue |
| C | LYS145 |
| C | ARG316 |
| C | GLY356 |
| C | HOH777 |
| A | GLU281 |
| site_id | AD2 |
| Number of Residues | 10 |
| Details | binding site for residue GOL C 503 |
| Chain | Residue |
| C | ILE76 |
| C | ARG114 |
| C | LEU117 |
| C | THR118 |
| C | SER119 |
| C | SER355 |
| C | HOH610 |
| C | HOH621 |
| C | HOH670 |
| C | HOH760 |
| site_id | AD3 |
| Number of Residues | 7 |
| Details | binding site for residue GOL C 504 |
| Chain | Residue |
| A | LYS139 |
| A | LYS140 |
| C | GLN417 |
| C | LEU418 |
| C | ASN420 |
| C | ARG441 |
| C | HOH618 |
| site_id | AD4 |
| Number of Residues | 5 |
| Details | binding site for residue GOL C 505 |
| Chain | Residue |
| C | PRO154 |
| C | GLY155 |
| C | THR156 |
| C | HOH667 |
| C | HOH709 |
| site_id | AD5 |
| Number of Residues | 11 |
| Details | binding site for residue GOL C 506 |
| Chain | Residue |
| A | LYS115 |
| A | GOL504 |
| C | GLY272 |
| C | ALA273 |
| C | ILE278 |
| C | GLY280 |
| C | GLU281 |
| C | ASN282 |
| C | CYS283 |
| C | HOH617 |
| C | HOH624 |
| site_id | AD6 |
| Number of Residues | 33 |
| Details | binding site for residue B12 D 601 |
| Chain | Residue |
| C | PRO194 |
| C | VAL195 |
| C | ALA226 |
| C | PHE245 |
| C | GLN246 |
| C | SER247 |
| C | GLU257 |
| C | PHE258 |
| C | SER295 |
| C | PHE329 |
| C | ILE330 |
| C | MET401 |
| C | LEU402 |
| C | ASN403 |
| C | 5AD501 |
| C | HOH619 |
| D | ARG141 |
| D | LEU169 |
| D | ARG206 |
| D | VAL207 |
| D | LYS208 |
| D | GLY227 |
| D | GLU228 |
| D | ARG229 |
| D | TYR241 |
| D | GLU253 |
| D | ARG256 |
| D | CYS258 |
| D | SER260 |
| D | HOH703 |
| D | HOH712 |
| D | HOH731 |
| D | HOH740 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00601, ECO:0000269|PubMed:20519496, ECO:0000269|PubMed:21142024, ECO:0007744|PDB:3ABO, ECO:0007744|PDB:3ABQ, ECO:0007744|PDB:3ABR, ECO:0007744|PDB:5YSN, ECO:0007744|PDB:5YSR |
| Chain | Residue | Details |
| B | VAL207 | |
| D | VAL207 | |
| A | ASP362 | |
| C | ARG160 | |
| C | GLU287 | |
| C | ASP362 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00601, ECO:0000269|PubMed:20519496, ECO:0000269|PubMed:21142024, ECO:0007744|PDB:3ABO, ECO:0007744|PDB:3ABQ, ECO:0007744|PDB:3ABR, ECO:0007744|PDB:3ANY, ECO:0007744|PDB:3AO0 |
| Chain | Residue | Details |
| B | GLU228 | |
| D | GLU228 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00601, ECO:0000269|PubMed:20519496, ECO:0000269|PubMed:21142024, ECO:0007744|PDB:3ABO, ECO:0007744|PDB:3ABR, ECO:0007744|PDB:3AO0, ECO:0007744|PDB:5YSN |
| Chain | Residue | Details |
| B | CYS258 | |
| D | CYS258 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00861, ECO:0000269|PubMed:20519496, ECO:0000269|PubMed:21142024, ECO:0007744|PDB:3ABO, ECO:0007744|PDB:3ABQ, ECO:0007744|PDB:3ANY, ECO:0007744|PDB:3AO0, ECO:0007744|PDB:5YSN |
| Chain | Residue | Details |
| A | GLN246 | |
| C | GLN246 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00861, ECO:0000305, ECO:0007744|PDB:3ABR, ECO:0007744|PDB:3ANY, ECO:0007744|PDB:3AO0 |
| Chain | Residue | Details |
| A | SER295 | |
| C | SER295 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00861, ECO:0000269|PubMed:20519496, ECO:0000269|PubMed:21142024, ECO:0007744|PDB:3ABO, ECO:0007744|PDB:3ABQ, ECO:0007744|PDB:3ANY, ECO:0007744|PDB:3AO0, ECO:0007744|PDB:5YSN, ECO:0007744|PDB:5YSR |
| Chain | Residue | Details |
| A | MET401 | |
| C | MET401 |
