5YPS
The structural basis of histone chaperoneVps75
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000775 | cellular_component | chromosome, centromeric region |
| A | 0000785 | cellular_component | chromatin |
| A | 0005634 | cellular_component | nucleus |
| A | 0005654 | cellular_component | nucleoplasm |
| A | 0006334 | biological_process | nucleosome assembly |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0140713 | molecular_function | histone chaperone activity |
| B | 0000775 | cellular_component | chromosome, centromeric region |
| B | 0000785 | cellular_component | chromatin |
| B | 0005634 | cellular_component | nucleus |
| B | 0005654 | cellular_component | nucleoplasm |
| B | 0006334 | biological_process | nucleosome assembly |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0140713 | molecular_function | histone chaperone activity |
| C | 0000775 | cellular_component | chromosome, centromeric region |
| C | 0000785 | cellular_component | chromatin |
| C | 0005634 | cellular_component | nucleus |
| C | 0005654 | cellular_component | nucleoplasm |
| C | 0006334 | biological_process | nucleosome assembly |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0140713 | molecular_function | histone chaperone activity |
| D | 0000775 | cellular_component | chromosome, centromeric region |
| D | 0000785 | cellular_component | chromatin |
| D | 0005634 | cellular_component | nucleus |
| D | 0005654 | cellular_component | nucleoplasm |
| D | 0006334 | biological_process | nucleosome assembly |
| D | 0046872 | molecular_function | metal ion binding |
| D | 0140713 | molecular_function | histone chaperone activity |
| E | 0000775 | cellular_component | chromosome, centromeric region |
| E | 0000785 | cellular_component | chromatin |
| E | 0005634 | cellular_component | nucleus |
| E | 0005654 | cellular_component | nucleoplasm |
| E | 0006334 | biological_process | nucleosome assembly |
| E | 0046872 | molecular_function | metal ion binding |
| E | 0140713 | molecular_function | histone chaperone activity |
| F | 0000775 | cellular_component | chromosome, centromeric region |
| F | 0000785 | cellular_component | chromatin |
| F | 0005634 | cellular_component | nucleus |
| F | 0005654 | cellular_component | nucleoplasm |
| F | 0006334 | biological_process | nucleosome assembly |
| F | 0046872 | molecular_function | metal ion binding |
| F | 0140713 | molecular_function | histone chaperone activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue CA A 301 |
| Chain | Residue |
| A | ASP189 |
| A | PHE191 |
| A | GLU192 |
| D | GLU192 |
| D | GLU194 |
| D | HOH401 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue CA A 302 |
| Chain | Residue |
| A | GLU196 |
| D | ASP193 |
| A | GLU147 |
| A | GLU192 |
| A | ASP193 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue 1PE A 303 |
| Chain | Residue |
| A | GLN43 |
| A | PHE47 |
| A | TYR51 |
| A | PRO207 |
| A | ASN208 |
| B | PHE32 |
| B | ASP36 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue 1PE A 304 |
| Chain | Residue |
| A | TYR98 |
| A | PRO100 |
| A | LYS108 |
| A | TYR125 |
| A | MSE127 |
| A | HOH427 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue 1PE A 305 |
| Chain | Residue |
| A | ASN48 |
| A | PRO100 |
| A | ASN101 |
| A | GLU102 |
| A | HOH407 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue PEG A 306 |
| Chain | Residue |
| A | SER78 |
| A | VAL79 |
| A | ILE81 |
| D | SER141 |
| site_id | AC7 |
| Number of Residues | 1 |
| Details | binding site for residue GOL A 307 |
| Chain | Residue |
| A | GLU33 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 308 |
| Chain | Residue |
| A | ASP36 |
| B | PHE47 |
| B | PRO207 |
| B | 1PE305 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue CA B 301 |
| Chain | Residue |
| B | ASP189 |
| B | PHE191 |
| B | GLU192 |
| C | GLU192 |
| C | GLU194 |
| C | HOH401 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for residue CA B 302 |
| Chain | Residue |
| B | GLU192 |
| B | GLU194 |
| B | HOH401 |
| C | ASP189 |
| C | PHE191 |
| C | GLU192 |
| site_id | AD2 |
| Number of Residues | 5 |
| Details | binding site for residue CA B 303 |
| Chain | Residue |
| B | GLU147 |
| B | GLU192 |
| B | ASP193 |
| B | GLU196 |
| C | ASP193 |
| site_id | AD3 |
| Number of Residues | 4 |
| Details | binding site for residue 1PE B 304 |
| Chain | Residue |
| B | TYR98 |
| B | PRO100 |
| B | LYS108 |
| B | MSE127 |
| site_id | AD4 |
| Number of Residues | 7 |
| Details | binding site for residue 1PE B 305 |
| Chain | Residue |
| A | GOL308 |
| B | GLN43 |
| B | TYR51 |
| B | VAL97 |
| B | ARG99 |
| B | ALA202 |
| B | GLU203 |
| site_id | AD5 |
| Number of Residues | 4 |
| Details | binding site for residue 1PE B 306 |
| Chain | Residue |
| B | GLU70 |
| B | GLU219 |
| B | GOL308 |
| D | GLU70 |
| site_id | AD6 |
| Number of Residues | 5 |
| Details | binding site for residue GOL B 308 |
| Chain | Residue |
| B | GLU219 |
| B | 1PE306 |
| D | ASN87 |
| D | GLU90 |
| D | 1PE305 |
| site_id | AD7 |
| Number of Residues | 5 |
| Details | binding site for residue CA C 301 |
| Chain | Residue |
| B | ASP193 |
| C | GLU147 |
| C | GLU192 |
| C | ASP193 |
| C | GLU196 |
| site_id | AD8 |
| Number of Residues | 6 |
| Details | binding site for residue 1PE C 302 |
| Chain | Residue |
| C | ASP36 |
| D | PHE47 |
| D | TYR51 |
| D | PRO207 |
| D | ASN208 |
| D | LYS211 |
| site_id | AD9 |
| Number of Residues | 9 |
| Details | binding site for residue 1PE C 303 |
| Chain | Residue |
| C | GLN43 |
| C | PHE47 |
| C | ASN48 |
| C | TYR51 |
| C | VAL97 |
| C | ARG99 |
| C | ALA202 |
| C | GLU203 |
| D | 1PE303 |
| site_id | AE1 |
| Number of Residues | 8 |
| Details | binding site for residue 1PE C 304 |
| Chain | Residue |
| C | TYR125 |
| C | MSE127 |
| F | GLU102 |
| F | PEG306 |
| C | TYR98 |
| C | PRO100 |
| C | ASN101 |
| C | LYS108 |
| site_id | AE2 |
| Number of Residues | 8 |
| Details | binding site for residue GOL C 305 |
| Chain | Residue |
| B | PHE191 |
| C | THR179 |
| C | TRP180 |
| C | SER182 |
| C | TRP183 |
| C | GLU194 |
| C | HOH401 |
| C | HOH419 |
| site_id | AE3 |
| Number of Residues | 8 |
| Details | binding site for residue PGE C 306 |
| Chain | Residue |
| A | ASP215 |
| A | GLU219 |
| B | SER141 |
| C | GLU70 |
| C | SER78 |
| C | ILE81 |
| C | PRO83 |
| C | ALA86 |
| site_id | AE4 |
| Number of Residues | 5 |
| Details | binding site for residue CA D 301 |
| Chain | Residue |
| A | ASP193 |
| D | GLU147 |
| D | GLU192 |
| D | ASP193 |
| D | GLU196 |
| site_id | AE5 |
| Number of Residues | 6 |
| Details | binding site for residue CA D 302 |
| Chain | Residue |
| A | GLU192 |
| A | GLU194 |
| A | HOH409 |
| D | ASP189 |
| D | PHE191 |
| D | GLU192 |
| site_id | AE6 |
| Number of Residues | 7 |
| Details | binding site for residue 1PE D 303 |
| Chain | Residue |
| C | GLN43 |
| C | PHE47 |
| C | TYR51 |
| C | PRO207 |
| C | ASN208 |
| C | 1PE303 |
| D | ASP36 |
| site_id | AE7 |
| Number of Residues | 5 |
| Details | binding site for residue 1PE D 304 |
| Chain | Residue |
| D | TYR98 |
| D | PRO100 |
| D | LYS108 |
| D | TYR125 |
| D | MSE127 |
| site_id | AE8 |
| Number of Residues | 10 |
| Details | binding site for residue 1PE D 305 |
| Chain | Residue |
| A | TRP160 |
| A | LYS161 |
| A | LYS162 |
| A | ASN163 |
| A | ASP165 |
| B | GOL308 |
| D | ASN87 |
| D | HIS91 |
| D | GLU117 |
| D | TYR118 |
| site_id | AE9 |
| Number of Residues | 5 |
| Details | binding site for residue PEG D 306 |
| Chain | Residue |
| D | GLN43 |
| D | TYR51 |
| D | VAL97 |
| D | ARG99 |
| D | ALA202 |
| site_id | AF1 |
| Number of Residues | 5 |
| Details | binding site for residue GOL D 307 |
| Chain | Residue |
| C | ASN220 |
| D | GLU120 |
| D | GLU159 |
| D | TRP160 |
| D | GOL308 |
| site_id | AF2 |
| Number of Residues | 4 |
| Details | binding site for residue GOL D 308 |
| Chain | Residue |
| C | ASN220 |
| D | GLU120 |
| D | GLU159 |
| D | GOL307 |
| site_id | AF3 |
| Number of Residues | 1 |
| Details | binding site for residue GOL D 309 |
| Chain | Residue |
| D | VAL44 |
| site_id | AF4 |
| Number of Residues | 6 |
| Details | binding site for residue CA E 301 |
| Chain | Residue |
| E | ASP189 |
| E | PHE191 |
| E | GLU192 |
| E | GLU192 |
| E | GLU194 |
| E | HOH420 |
| site_id | AF5 |
| Number of Residues | 5 |
| Details | binding site for residue CA E 302 |
| Chain | Residue |
| E | GLU147 |
| E | GLU192 |
| E | ASP193 |
| E | ASP193 |
| E | GLU196 |
| site_id | AF6 |
| Number of Residues | 4 |
| Details | binding site for residue 1PE E 303 |
| Chain | Residue |
| E | PRO100 |
| E | LYS108 |
| E | TYR125 |
| E | MSE127 |
| site_id | AF7 |
| Number of Residues | 9 |
| Details | binding site for residue 1PE E 304 |
| Chain | Residue |
| E | ASP36 |
| E | LEU39 |
| E | 1PE305 |
| F | GLN43 |
| F | PHE47 |
| F | TYR51 |
| F | PRO207 |
| F | ASN208 |
| F | 1PE305 |
| site_id | AF8 |
| Number of Residues | 10 |
| Details | binding site for residue 1PE E 305 |
| Chain | Residue |
| E | LEU40 |
| E | GLN43 |
| E | VAL44 |
| E | TYR51 |
| E | VAL97 |
| E | ARG99 |
| E | ALA202 |
| E | GLU203 |
| E | 1PE304 |
| F | 1PE303 |
| site_id | AF9 |
| Number of Residues | 9 |
| Details | binding site for residue 1PE E 306 |
| Chain | Residue |
| E | GLU120 |
| E | GLU159 |
| E | TRP160 |
| E | LYS161 |
| E | LYS162 |
| E | ASN163 |
| E | LYS164 |
| E | ASP165 |
| E | ARG168 |
| site_id | AG1 |
| Number of Residues | 4 |
| Details | binding site for residue PEG E 307 |
| Chain | Residue |
| E | VAL44 |
| E | ARG99 |
| E | PRO100 |
| E | HOH416 |
| site_id | AG2 |
| Number of Residues | 3 |
| Details | binding site for residue GOL E 308 |
| Chain | Residue |
| E | ASN87 |
| E | GLU90 |
| F | GLU219 |
| site_id | AG3 |
| Number of Residues | 5 |
| Details | binding site for residue GOL E 309 |
| Chain | Residue |
| B | TYR132 |
| B | SER133 |
| B | ILE152 |
| E | ARG131 |
| E | ILE152 |
| site_id | AG4 |
| Number of Residues | 6 |
| Details | binding site for residue GOL E 310 |
| Chain | Residue |
| E | GLN169 |
| E | THR173 |
| E | PRO175 |
| E | LYS186 |
| E | GLU187 |
| E | ASN188 |
| site_id | AG5 |
| Number of Residues | 6 |
| Details | binding site for residue CA F 301 |
| Chain | Residue |
| F | ASP189 |
| F | PHE191 |
| F | GLU192 |
| F | GLU192 |
| F | GLU194 |
| F | HOH404 |
| site_id | AG6 |
| Number of Residues | 5 |
| Details | binding site for residue CA F 302 |
| Chain | Residue |
| F | GLU147 |
| F | GLU192 |
| F | ASP193 |
| F | ASP193 |
| F | GLU196 |
| site_id | AG7 |
| Number of Residues | 9 |
| Details | binding site for residue 1PE F 303 |
| Chain | Residue |
| E | GLN43 |
| E | PHE47 |
| E | TYR51 |
| E | PRO207 |
| E | ASN208 |
| E | 1PE305 |
| F | PHE32 |
| F | ASP36 |
| F | LEU39 |
| site_id | AG8 |
| Number of Residues | 5 |
| Details | binding site for residue 1PE F 304 |
| Chain | Residue |
| F | PRO100 |
| F | ASN101 |
| F | LYS108 |
| F | TYR125 |
| F | MSE127 |
| site_id | AG9 |
| Number of Residues | 10 |
| Details | binding site for residue 1PE F 305 |
| Chain | Residue |
| E | 1PE304 |
| F | GLN43 |
| F | VAL44 |
| F | ASN48 |
| F | TYR51 |
| F | VAL97 |
| F | TYR98 |
| F | ARG99 |
| F | ALA202 |
| F | GLU203 |
| site_id | AH1 |
| Number of Residues | 4 |
| Details | binding site for residue PEG F 306 |
| Chain | Residue |
| C | 1PE304 |
| F | GLU33 |
| F | LYS41 |
| F | ARG105 |
| site_id | AH2 |
| Number of Residues | 5 |
| Details | binding site for residue PEG F 307 |
| Chain | Residue |
| E | SER78 |
| E | ILE81 |
| E | SER141 |
| F | ASP215 |
| F | GLU219 |
| site_id | AH3 |
| Number of Residues | 5 |
| Details | binding site for residue GOL F 308 |
| Chain | Residue |
| E | ASP215 |
| F | SER78 |
| F | ILE81 |
| F | PRO83 |
| F | SER141 |
| site_id | AH4 |
| Number of Residues | 4 |
| Details | binding site for residue GOL F 309 |
| Chain | Residue |
| E | GLU70 |
| F | GLU70 |
| F | ALA216 |
| F | GOL310 |
| site_id | AH5 |
| Number of Residues | 4 |
| Details | binding site for residue GOL F 310 |
| Chain | Residue |
| E | GLU70 |
| E | GLU219 |
| F | GLU70 |
| F | GOL309 |
