Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

5YPS

The structural basis of histone chaperoneVps75

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000785	cellular_component	chromatin
A	0003682	molecular_function	chromatin binding
A	0005634	cellular_component	nucleus
A	0006334	biological_process	nucleosome assembly
A	0042393	molecular_function	histone binding
A	0046872	molecular_function	metal ion binding
B	0000785	cellular_component	chromatin
B	0003682	molecular_function	chromatin binding
B	0005634	cellular_component	nucleus
B	0006334	biological_process	nucleosome assembly
B	0042393	molecular_function	histone binding
B	0046872	molecular_function	metal ion binding
C	0000785	cellular_component	chromatin
C	0003682	molecular_function	chromatin binding
C	0005634	cellular_component	nucleus
C	0006334	biological_process	nucleosome assembly
C	0042393	molecular_function	histone binding
C	0046872	molecular_function	metal ion binding
D	0000785	cellular_component	chromatin
D	0003682	molecular_function	chromatin binding
D	0005634	cellular_component	nucleus
D	0006334	biological_process	nucleosome assembly
D	0042393	molecular_function	histone binding
D	0046872	molecular_function	metal ion binding
E	0000785	cellular_component	chromatin
E	0003682	molecular_function	chromatin binding
E	0005634	cellular_component	nucleus
E	0006334	biological_process	nucleosome assembly
E	0042393	molecular_function	histone binding
E	0046872	molecular_function	metal ion binding
F	0000785	cellular_component	chromatin
F	0003682	molecular_function	chromatin binding
F	0005634	cellular_component	nucleus
F	0006334	biological_process	nucleosome assembly
F	0042393	molecular_function	histone binding
F	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue CA A 301

Chain	Residue
A	ASP189
A	PHE191
A	GLU192
D	GLU192
D	GLU194
D	HOH401

site_id	AC2
Number of Residues	5
Details	binding site for residue CA A 302

Chain	Residue
A	GLU196
D	ASP193
A	GLU147
A	GLU192
A	ASP193

site_id	AC3
Number of Residues	7
Details	binding site for residue 1PE A 303

Chain	Residue
A	GLN43
A	PHE47
A	TYR51
A	PRO207
A	ASN208
B	PHE32
B	ASP36

site_id	AC4
Number of Residues	6
Details	binding site for residue 1PE A 304

Chain	Residue
A	TYR98
A	PRO100
A	LYS108
A	TYR125
A	MSE127
A	HOH427

site_id	AC5
Number of Residues	5
Details	binding site for residue 1PE A 305

Chain	Residue
A	ASN48
A	PRO100
A	ASN101
A	GLU102
A	HOH407

site_id	AC6
Number of Residues	4
Details	binding site for residue PEG A 306

Chain	Residue
A	SER78
A	VAL79
A	ILE81
D	SER141

site_id	AC7
Number of Residues	1
Details	binding site for residue GOL A 307

Chain	Residue
A	GLU33

site_id	AC8
Number of Residues	4
Details	binding site for residue GOL A 308

Chain	Residue
A	ASP36
B	PHE47
B	PRO207
B	1PE305

site_id	AC9
Number of Residues	6
Details	binding site for residue CA B 301

Chain	Residue
B	ASP189
B	PHE191
B	GLU192
C	GLU192
C	GLU194
C	HOH401

site_id	AD1
Number of Residues	6
Details	binding site for residue CA B 302

Chain	Residue
B	GLU192
B	GLU194
B	HOH401
C	ASP189
C	PHE191
C	GLU192

site_id	AD2
Number of Residues	5
Details	binding site for residue CA B 303

Chain	Residue
B	GLU147
B	GLU192
B	ASP193
B	GLU196
C	ASP193

site_id	AD3
Number of Residues	4
Details	binding site for residue 1PE B 304

Chain	Residue
B	TYR98
B	PRO100
B	LYS108
B	MSE127

site_id	AD4
Number of Residues	7
Details	binding site for residue 1PE B 305

Chain	Residue
A	GOL308
B	GLN43
B	TYR51
B	VAL97
B	ARG99
B	ALA202
B	GLU203

site_id	AD5
Number of Residues	4
Details	binding site for residue 1PE B 306

Chain	Residue
B	GLU70
B	GLU219
B	GOL308
D	GLU70

site_id	AD6
Number of Residues	5
Details	binding site for residue GOL B 308

Chain	Residue
B	GLU219
B	1PE306
D	ASN87
D	GLU90
D	1PE305

site_id	AD7
Number of Residues	5
Details	binding site for residue CA C 301

Chain	Residue
B	ASP193
C	GLU147
C	GLU192
C	ASP193
C	GLU196

site_id	AD8
Number of Residues	6
Details	binding site for residue 1PE C 302

Chain	Residue
C	ASP36
D	PHE47
D	TYR51
D	PRO207
D	ASN208
D	LYS211

site_id	AD9
Number of Residues	9
Details	binding site for residue 1PE C 303

Chain	Residue
C	GLN43
C	PHE47
C	ASN48
C	TYR51
C	VAL97
C	ARG99
C	ALA202
C	GLU203
D	1PE303

site_id	AE1
Number of Residues	8
Details	binding site for residue 1PE C 304

Chain	Residue
C	TYR125
C	MSE127
F	GLU102
F	PEG306
C	TYR98
C	PRO100
C	ASN101
C	LYS108

site_id	AE2
Number of Residues	8
Details	binding site for residue GOL C 305

Chain	Residue
B	PHE191
C	THR179
C	TRP180
C	SER182
C	TRP183
C	GLU194
C	HOH401
C	HOH419

site_id	AE3
Number of Residues	8
Details	binding site for residue PGE C 306

Chain	Residue
A	ASP215
A	GLU219
B	SER141
C	GLU70
C	SER78
C	ILE81
C	PRO83
C	ALA86

site_id	AE4
Number of Residues	5
Details	binding site for residue CA D 301

Chain	Residue
A	ASP193
D	GLU147
D	GLU192
D	ASP193
D	GLU196

site_id	AE5
Number of Residues	6
Details	binding site for residue CA D 302

Chain	Residue
A	GLU192
A	GLU194
A	HOH409
D	ASP189
D	PHE191
D	GLU192

site_id	AE6
Number of Residues	7
Details	binding site for residue 1PE D 303

Chain	Residue
C	GLN43
C	PHE47
C	TYR51
C	PRO207
C	ASN208
C	1PE303
D	ASP36

site_id	AE7
Number of Residues	5
Details	binding site for residue 1PE D 304

Chain	Residue
D	TYR98
D	PRO100
D	LYS108
D	TYR125
D	MSE127

site_id	AE8
Number of Residues	10
Details	binding site for residue 1PE D 305

Chain	Residue
A	TRP160
A	LYS161
A	LYS162
A	ASN163
A	ASP165
B	GOL308
D	ASN87
D	HIS91
D	GLU117
D	TYR118

site_id	AE9
Number of Residues	5
Details	binding site for residue PEG D 306

Chain	Residue
D	GLN43
D	TYR51
D	VAL97
D	ARG99
D	ALA202

site_id	AF1
Number of Residues	5
Details	binding site for residue GOL D 307

Chain	Residue
C	ASN220
D	GLU120
D	GLU159
D	TRP160
D	GOL308

site_id	AF2
Number of Residues	4
Details	binding site for residue GOL D 308

Chain	Residue
C	ASN220
D	GLU120
D	GLU159
D	GOL307

site_id	AF3
Number of Residues	1
Details	binding site for residue GOL D 309

Chain	Residue
D	VAL44

site_id	AF4
Number of Residues	6
Details	binding site for residue CA E 301

Chain	Residue
E	ASP189
E	PHE191
E	GLU192
E	GLU192
E	GLU194
E	HOH420

site_id	AF5
Number of Residues	5
Details	binding site for residue CA E 302

Chain	Residue
E	GLU147
E	GLU192
E	ASP193
E	ASP193
E	GLU196

site_id	AF6
Number of Residues	4
Details	binding site for residue 1PE E 303

Chain	Residue
E	PRO100
E	LYS108
E	TYR125
E	MSE127

site_id	AF7
Number of Residues	9
Details	binding site for residue 1PE E 304

Chain	Residue
E	ASP36
E	LEU39
E	1PE305
F	GLN43
F	PHE47
F	TYR51
F	PRO207
F	ASN208
F	1PE305

site_id	AF8
Number of Residues	10
Details	binding site for residue 1PE E 305

Chain	Residue
E	LEU40
E	GLN43
E	VAL44
E	TYR51
E	VAL97
E	ARG99
E	ALA202
E	GLU203
E	1PE304
F	1PE303

site_id	AF9
Number of Residues	9
Details	binding site for residue 1PE E 306

Chain	Residue
E	GLU120
E	GLU159
E	TRP160
E	LYS161
E	LYS162
E	ASN163
E	LYS164
E	ASP165
E	ARG168

site_id	AG1
Number of Residues	4
Details	binding site for residue PEG E 307

Chain	Residue
E	VAL44
E	ARG99
E	PRO100
E	HOH416

site_id	AG2
Number of Residues	3
Details	binding site for residue GOL E 308

Chain	Residue
E	ASN87
E	GLU90
F	GLU219

site_id	AG3
Number of Residues	5
Details	binding site for residue GOL E 309

Chain	Residue
B	TYR132
B	SER133
B	ILE152
E	ARG131
E	ILE152

site_id	AG4
Number of Residues	6
Details	binding site for residue GOL E 310

Chain	Residue
E	GLN169
E	THR173
E	PRO175
E	LYS186
E	GLU187
E	ASN188

site_id	AG5
Number of Residues	6
Details	binding site for residue CA F 301

Chain	Residue
F	ASP189
F	PHE191
F	GLU192
F	GLU192
F	GLU194
F	HOH404

site_id	AG6
Number of Residues	5
Details	binding site for residue CA F 302

Chain	Residue
F	GLU147
F	GLU192
F	ASP193
F	ASP193
F	GLU196

site_id	AG7
Number of Residues	9
Details	binding site for residue 1PE F 303

Chain	Residue
E	GLN43
E	PHE47
E	TYR51
E	PRO207
E	ASN208
E	1PE305
F	PHE32
F	ASP36
F	LEU39

site_id	AG8
Number of Residues	5
Details	binding site for residue 1PE F 304

Chain	Residue
F	PRO100
F	ASN101
F	LYS108
F	TYR125
F	MSE127

site_id	AG9
Number of Residues	10
Details	binding site for residue 1PE F 305

Chain	Residue
E	1PE304
F	GLN43
F	VAL44
F	ASN48
F	TYR51
F	VAL97
F	TYR98
F	ARG99
F	ALA202
F	GLU203

site_id	AH1
Number of Residues	4
Details	binding site for residue PEG F 306

Chain	Residue
C	1PE304
F	GLU33
F	LYS41
F	ARG105

site_id	AH2
Number of Residues	5
Details	binding site for residue PEG F 307

Chain	Residue
E	SER78
E	ILE81
E	SER141
F	ASP215
F	GLU219

site_id	AH3
Number of Residues	5
Details	binding site for residue GOL F 308

Chain	Residue
E	ASP215
F	SER78
F	ILE81
F	PRO83
F	SER141

site_id	AH4
Number of Residues	4
Details	binding site for residue GOL F 309

Chain	Residue
E	GLU70
F	GLU70
F	ALA216
F	GOL310

site_id	AH5
Number of Residues	4
Details	binding site for residue GOL F 310

Chain	Residue
E	GLU70
E	GLU219
F	GLU70
F	GOL309

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)