5YP3
Crystal structure of dipeptidyl peptidase IV (DPP IV) with Ile-Pro from Pseudoxanthomonas mexicana
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006508 | biological_process | proteolysis |
| A | 0008236 | molecular_function | serine-type peptidase activity |
| B | 0006508 | biological_process | proteolysis |
| B | 0008236 | molecular_function | serine-type peptidase activity |
| C | 0006508 | biological_process | proteolysis |
| C | 0008236 | molecular_function | serine-type peptidase activity |
| D | 0006508 | biological_process | proteolysis |
| D | 0008236 | molecular_function | serine-type peptidase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | binding site for residue GOL D 803 |
| Chain | Residue |
| D | PRO339 |
| D | HOH965 |
| D | HOH969 |
| D | GLU357 |
| D | THR566 |
| D | PRO567 |
| D | ARG568 |
| D | ARG569 |
| D | GLY570 |
| D | ALA571 |
| D | GLY574 |
| site_id | AC2 |
| Number of Residues | 12 |
| Details | binding site for Di-peptide ILE A 801 and PRO A 802 |
| Chain | Residue |
| A | ARG106 |
| A | GLU208 |
| A | GLU209 |
| A | TYR527 |
| A | ALA531 |
| A | SER613 |
| A | ASN614 |
| A | TYR645 |
| A | TYR649 |
| A | ASN691 |
| A | VAL692 |
| A | HIS721 |
| site_id | AC3 |
| Number of Residues | 12 |
| Details | binding site for Di-peptide ILE B 801 and PRO B 802 |
| Chain | Residue |
| B | ARG106 |
| B | GLU208 |
| B | GLU209 |
| B | TYR527 |
| B | ALA531 |
| B | SER613 |
| B | ASN614 |
| B | VAL639 |
| B | TYR645 |
| B | TYR649 |
| B | ASN691 |
| B | HIS721 |
| site_id | AC4 |
| Number of Residues | 13 |
| Details | binding site for Di-peptide PRO B 802 and SER B 613 |
| Chain | Residue |
| B | TYR527 |
| B | TRP612 |
| B | ASN614 |
| B | GLY615 |
| B | GLY616 |
| B | TYR617 |
| B | GLY636 |
| B | ALA637 |
| B | VAL639 |
| B | TYR645 |
| B | TYR649 |
| B | HIS721 |
| B | ILE801 |
| site_id | AC5 |
| Number of Residues | 10 |
| Details | binding site for Di-peptide ILE C 801 and PRO C 802 |
| Chain | Residue |
| C | ARG106 |
| C | GLU208 |
| C | GLU209 |
| C | TYR527 |
| C | ALA531 |
| C | SER613 |
| C | ASN614 |
| C | TYR645 |
| C | TYR649 |
| C | ASN691 |
| site_id | AC6 |
| Number of Residues | 12 |
| Details | binding site for Di-peptide PRO C 802 and SER C 613 |
| Chain | Residue |
| C | TYR527 |
| C | TRP612 |
| C | ASN614 |
| C | GLY615 |
| C | GLY616 |
| C | TYR617 |
| C | GLY636 |
| C | ALA637 |
| C | TYR645 |
| C | TYR649 |
| C | HIS721 |
| C | ILE801 |
| site_id | AC7 |
| Number of Residues | 12 |
| Details | binding site for Di-peptide ILE D 801 and PRO D 802 |
| Chain | Residue |
| D | ARG106 |
| D | GLU208 |
| D | GLU209 |
| D | TYR527 |
| D | ALA531 |
| D | SER613 |
| D | ASN614 |
| D | TYR645 |
| D | TYR649 |
| D | ASN691 |
| D | VAL692 |
| D | HOH959 |
| site_id | AC8 |
| Number of Residues | 15 |
| Details | binding site for Di-peptide PRO D 802 and SER D 613 |
| Chain | Residue |
| D | TYR527 |
| D | TRP612 |
| D | ASN614 |
| D | GLY615 |
| D | GLY616 |
| D | TYR617 |
| D | GLY636 |
| D | ALA637 |
| D | PRO638 |
| D | TYR645 |
| D | TYR649 |
| D | VAL692 |
| D | HIS721 |
| D | ILE801 |
| D | HOH959 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Active site: {"description":"Charge relay system","evidences":[{"source":"UniProtKB","id":"Q12884","evidenceCode":"ECO:0000250"},{"source":"PROSITE-ProRule","id":"PRU10084","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | Active site: {"description":"Charge relay system","evidences":[{"source":"UniProtKB","id":"Q12884","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"Q12884","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
