5YOL

Crystal structure of octameric form of Nucleoside diphosphate kinase from Acinetobacter baumannii at 2.2 A resolution

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004550	molecular_function	nucleoside diphosphate kinase activity
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0006183	biological_process	GTP biosynthetic process
A	0006228	biological_process	UTP biosynthetic process
A	0006241	biological_process	CTP biosynthetic process
A	0009117	biological_process	nucleotide metabolic process
A	0009142	biological_process	nucleoside triphosphate biosynthetic process
A	0016301	molecular_function	kinase activity
A	0046872	molecular_function	metal ion binding
B	0004550	molecular_function	nucleoside diphosphate kinase activity
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0006183	biological_process	GTP biosynthetic process
B	0006228	biological_process	UTP biosynthetic process
B	0006241	biological_process	CTP biosynthetic process
B	0009117	biological_process	nucleotide metabolic process
B	0009142	biological_process	nucleoside triphosphate biosynthetic process
B	0016301	molecular_function	kinase activity
B	0046872	molecular_function	metal ion binding
C	0004550	molecular_function	nucleoside diphosphate kinase activity
C	0005524	molecular_function	ATP binding
C	0005737	cellular_component	cytoplasm
C	0006183	biological_process	GTP biosynthetic process
C	0006228	biological_process	UTP biosynthetic process
C	0006241	biological_process	CTP biosynthetic process
C	0009117	biological_process	nucleotide metabolic process
C	0009142	biological_process	nucleoside triphosphate biosynthetic process
C	0016301	molecular_function	kinase activity
C	0046872	molecular_function	metal ion binding
D	0004550	molecular_function	nucleoside diphosphate kinase activity
D	0005524	molecular_function	ATP binding
D	0005737	cellular_component	cytoplasm
D	0006183	biological_process	GTP biosynthetic process
D	0006228	biological_process	UTP biosynthetic process
D	0006241	biological_process	CTP biosynthetic process
D	0009117	biological_process	nucleotide metabolic process
D	0009142	biological_process	nucleoside triphosphate biosynthetic process
D	0016301	molecular_function	kinase activity
D	0046872	molecular_function	metal ion binding
E	0004550	molecular_function	nucleoside diphosphate kinase activity
E	0005524	molecular_function	ATP binding
E	0005737	cellular_component	cytoplasm
E	0006183	biological_process	GTP biosynthetic process
E	0006228	biological_process	UTP biosynthetic process
E	0006241	biological_process	CTP biosynthetic process
E	0009117	biological_process	nucleotide metabolic process
E	0009142	biological_process	nucleoside triphosphate biosynthetic process
E	0016301	molecular_function	kinase activity
E	0046872	molecular_function	metal ion binding
F	0004550	molecular_function	nucleoside diphosphate kinase activity
F	0005524	molecular_function	ATP binding
F	0005737	cellular_component	cytoplasm
F	0006183	biological_process	GTP biosynthetic process
F	0006228	biological_process	UTP biosynthetic process
F	0006241	biological_process	CTP biosynthetic process
F	0009117	biological_process	nucleotide metabolic process
F	0009142	biological_process	nucleoside triphosphate biosynthetic process
F	0016301	molecular_function	kinase activity
F	0046872	molecular_function	metal ion binding
G	0004550	molecular_function	nucleoside diphosphate kinase activity
G	0005524	molecular_function	ATP binding
G	0005737	cellular_component	cytoplasm
G	0006183	biological_process	GTP biosynthetic process
G	0006228	biological_process	UTP biosynthetic process
G	0006241	biological_process	CTP biosynthetic process
G	0009117	biological_process	nucleotide metabolic process
G	0009142	biological_process	nucleoside triphosphate biosynthetic process
G	0016301	molecular_function	kinase activity
G	0046872	molecular_function	metal ion binding
H	0004550	molecular_function	nucleoside diphosphate kinase activity
H	0005524	molecular_function	ATP binding
H	0005737	cellular_component	cytoplasm
H	0006183	biological_process	GTP biosynthetic process
H	0006228	biological_process	UTP biosynthetic process
H	0006241	biological_process	CTP biosynthetic process
H	0009117	biological_process	nucleotide metabolic process
H	0009142	biological_process	nucleoside triphosphate biosynthetic process
H	0016301	molecular_function	kinase activity
H	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue MG A 201

Chain	Residue
A	ASN136
A	HOH316
A	HOH320
A	HOH375
G	ASP46

---

site_id	AC2
Number of Residues	5
Details	binding site for residue MG A 202

Chain	Residue
F	HOH343
A	ASP120
A	HOH303
A	HOH365
F	HOH303

---

site_id	AC3
Number of Residues	4
Details	binding site for residue MG B 201

Chain	Residue
B	ASN136
B	HOH331
F	ASP46
F	HOH313

---

site_id	AC4
Number of Residues	3
Details	binding site for residue MG C 201

Chain	Residue
C	HOH303
C	HOH345
E	HOH337

---

site_id	AC5
Number of Residues	5
Details	binding site for residue MG D 201

Chain	Residue
D	ASN136
D	HOH343
D	HOH370
H	ASP46
H	HOH302

---

site_id	AC6
Number of Residues	7
Details	binding site for residue MG E 201

Chain	Residue
A	ASP112
E	GLU53
E	ASP120
E	SER124
E	HOH301
E	HOH307
E	HOH314

---

site_id	AC7
Number of Residues	7
Details	binding site for residue MG E 202

Chain	Residue
C	ASP46
C	HOH338
C	HOH346
E	ASN136
E	HOH326
E	HOH335
E	HOH338

---

site_id	AC8
Number of Residues	5
Details	binding site for residue MG F 201

Chain	Residue
B	ASP46
F	ASN136
F	HOH306
F	HOH320
F	HOH337

---

site_id	AC9
Number of Residues	6
Details	binding site for residue MG G 201

Chain	Residue
A	ASP46
A	HOH329
A	HOH343
A	HOH372
G	ASN136
G	HOH333

---

site_id	AD1
Number of Residues	6
Details	binding site for residue MG G 202

Chain	Residue
B	ASP120
B	HOH305
B	HOH344
G	ASP112
G	HOH302
G	HOH355

---

site_id	AD2
Number of Residues	7
Details	binding site for residue MG H 201

Chain	Residue
D	ASP46
D	HOH318
D	HOH351
D	HOH369
H	ASN136
H	HOH308
H	HOH359

---

site_id	AD3
Number of Residues	6
Details	binding site for residue MG H 202

Chain	Residue
B	ASP112
H	GLU53
H	ASP120
H	SER124
H	HOH306
H	HOH311

---

Functional Information from PROSITE/UniProt

site_id	PS00469
Number of Residues	9
Details	NDPK Nucleoside diphosphate kinase (NDPK) active site signature. NaaHGSDSV

Chain	Residue	Details
A	ASN114-VAL122

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