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5YNF

Crystal structure of MERS-CoV nsp16/nsp10 complex bound to m7GpppA

Functional Information from GO Data
ChainGOidnamespacecontents
A0004483molecular_functionmRNA (nucleoside-2'-O-)-methyltransferase activity
B0003723molecular_functionRNA binding
B0008270molecular_functionzinc ion binding
B0019079biological_processviral genome replication
Functional Information from PDB Data
site_idAC1
Number of Residues18
Detailsbinding site for residue GTA A 401
ChainResidue
ACYS25
AGLU173
AHIS174
ASER201
ASER202
AGLU203
AHOH507
AHOH538
AHOH551
AHOH567
ALEU27
ATYR30
ALYS31
ALYS46
ATYR132
ALYS137
ALYS170
ATHR172

site_idAC2
Number of Residues4
Detailsbinding site for residue ZN B 201
ChainResidue
BCYS74
BCYS77
BHIS83
BCYS90

site_idAC3
Number of Residues5
Detailsbinding site for residue ZN B 202
ChainResidue
BCYS117
BVAL119
BCYS120
BCYS128
BCYS130

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PDB entries from 2024-11-06

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