5YMR

The Crystal Structure of IseG

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0016740	molecular_function	transferase activity
A	0016829	molecular_function	lyase activity
A	0046306	biological_process	alkanesulfonate catabolic process
B	0003824	molecular_function	catalytic activity
B	0016740	molecular_function	transferase activity
B	0016829	molecular_function	lyase activity
B	0046306	biological_process	alkanesulfonate catabolic process
C	0003824	molecular_function	catalytic activity
C	0016740	molecular_function	transferase activity
C	0016829	molecular_function	lyase activity
C	0046306	biological_process	alkanesulfonate catabolic process
D	0003824	molecular_function	catalytic activity
D	0016740	molecular_function	transferase activity
D	0016829	molecular_function	lyase activity
D	0046306	biological_process	alkanesulfonate catabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	binding site for residue 8X3 B 901

Chain	Residue
B	ARG187
B	HOH1124
B	ILE190
B	GLN191
B	THR310
B	GLY465
B	CYS466
B	GLU468
B	ARG676
B	PHE680

---

site_id	AC2
Number of Residues	5
Details	binding site for residue GOL B 902

Chain	Residue
B	ARG31
B	HIS88
B	LEU90
B	GLU269
B	GLU341

---

site_id	AC3
Number of Residues	4
Details	binding site for residue GOL B 903

Chain	Residue
A	PHE726
B	ARG385
B	ASP386
B	ARG416

---

site_id	AC4
Number of Residues	11
Details	binding site for residue 8X3 D 901

Chain	Residue
D	ARG187
D	ILE190
D	GLN191
D	THR310
D	GLY465
D	CYS466
D	GLU468
D	TYR585
D	ARG676
D	PHE680
D	HOH1038

---

site_id	AC5
Number of Residues	2
Details	binding site for residue GOL D 902

Chain	Residue
C	PHE726
D	ARG416

---

site_id	AC6
Number of Residues	11
Details	binding site for residue 8X3 C 901

Chain	Residue
C	ARG187
C	ILE190
C	GLN191
C	THR310
C	GLY465
C	CYS466
C	GLU468
C	TYR585
C	ARG676
C	PHE680
C	HOH1121

---

site_id	AC7
Number of Residues	4
Details	binding site for residue GOL C 902

Chain	Residue
C	ASP386
C	ARG416
D	GLN723
D	PHE726

---

site_id	AC8
Number of Residues	10
Details	binding site for residue 8X3 A 901

Chain	Residue
A	ARG187
A	ILE190
A	GLN191
A	THR310
A	GLY465
A	CYS466
A	GLU468
A	ARG676
A	PHE680
A	HOH1133

---

site_id	AC9
Number of Residues	5
Details	binding site for residue GOL A 902

Chain	Residue
A	ARG31
A	HIS88
A	LEU90
A	GLU269
A	GLU341

---

site_id	AD1
Number of Residues	6
Details	binding site for residue GOL A 903

Chain	Residue
A	MET58
A	LEU66
A	ARG69
A	LYS149
A	ARG551
A	HIS552

---

Functional Information from PROSITE/UniProt

site_id	PS00850
Number of Residues	9
Details	GLY_RADICAL_1 Glycine radical domain signature. IvRIAGYSA

Chain	Residue	Details
B	ILE798-ALA806

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	ACT_SITE: Cysteine radical intermediate => ECO:0000305|PubMed:30962433

Chain	Residue	Details
B	CYS466
D	CYS466
C	CYS466
A	CYS466

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	ACT_SITE: Proton acceptor => ECO:0000305|PubMed:30962433

Chain	Residue	Details
B	GLU468
D	GLU468
C	GLU468
A	GLU468

---

site_id	SWS_FT_FI3
Number of Residues	16
Details	BINDING: BINDING => ECO:0000269|PubMed:30962433

Chain	Residue	Details
B	ARG187
C	GLN191
C	CYS466
C	ARG676
A	ARG187
A	GLN191
A	CYS466
A	ARG676
B	GLN191
B	CYS466
B	ARG676
D	ARG187
D	GLN191
D	CYS466
D	ARG676
C	ARG187

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	MOD_RES: Glycine radical => ECO:0000255|PROSITE-ProRule:PRU00493

Chain	Residue	Details
B	GLY803
D	GLY803
C	GLY803
A	GLY803

---