5YKD

Crystal structure of dihydropyrimidinase from Pseudomonas aeruginosa PAO1 at 2.17 angstrom resolution

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004157	molecular_function	dihydropyrimidinase activity
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0016787	molecular_function	hydrolase activity
A	0016810	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
A	0016812	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
A	0046872	molecular_function	metal ion binding
A	0055086	biological_process	nucleobase-containing small molecule metabolic process
A	0072527	biological_process	pyrimidine-containing compound metabolic process
B	0004157	molecular_function	dihydropyrimidinase activity
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0016787	molecular_function	hydrolase activity
B	0016810	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
B	0016812	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
B	0046872	molecular_function	metal ion binding
B	0055086	biological_process	nucleobase-containing small molecule metabolic process
B	0072527	biological_process	pyrimidine-containing compound metabolic process
C	0004157	molecular_function	dihydropyrimidinase activity
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0016787	molecular_function	hydrolase activity
C	0016810	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
C	0016812	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
C	0046872	molecular_function	metal ion binding
C	0055086	biological_process	nucleobase-containing small molecule metabolic process
C	0072527	biological_process	pyrimidine-containing compound metabolic process
D	0004157	molecular_function	dihydropyrimidinase activity
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0016787	molecular_function	hydrolase activity
D	0016810	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
D	0016812	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
D	0046872	molecular_function	metal ion binding
D	0055086	biological_process	nucleobase-containing small molecule metabolic process
D	0072527	biological_process	pyrimidine-containing compound metabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue ZN A 501

Chain	Residue
A	KCX150
A	HIS183
A	HIS239
A	ZN502

---

site_id	AC2
Number of Residues	5
Details	binding site for residue ZN A 502

Chain	Residue
A	HIS59
A	HIS61
A	KCX150
A	ASP316
A	ZN501

---

site_id	AC3
Number of Residues	4
Details	binding site for residue ZN B 501

Chain	Residue
B	KCX150
B	HIS183
B	HIS239
B	ZN502

---

site_id	AC4
Number of Residues	5
Details	binding site for residue ZN B 502

Chain	Residue
B	HIS59
B	HIS61
B	KCX150
B	ASP316
B	ZN501

---

site_id	AC5
Number of Residues	4
Details	binding site for residue ZN C 501

Chain	Residue
C	KCX150
C	HIS183
C	HIS239
C	ZN502

---

site_id	AC6
Number of Residues	5
Details	binding site for residue ZN C 502

Chain	Residue
C	HIS59
C	HIS61
C	KCX150
C	ASP316
C	ZN501

---

site_id	AC7
Number of Residues	5
Details	binding site for residue ZN D 501

Chain	Residue
D	HIS59
D	HIS61
D	KCX150
D	ASP316
D	ZN502

---

site_id	AC8
Number of Residues	5
Details	binding site for residue ZN D 502

Chain	Residue
D	KCX150
D	HIS183
D	HIS239
D	ZN501
D	HOH650

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	32
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"Q9P903","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	Binding site: {"description":"via carbamate group","evidences":[{"source":"UniProtKB","id":"Q9P903","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	Modified residue: {"description":"N6-carboxylysine","evidences":[{"source":"UniProtKB","id":"Q9P903","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---