Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 20 |
| Details | binding site for residue 8VO A 401 |
| Chain | Residue |
| A | ASP36 |
| A | THR219 |
| A | SER220 |
| A | LEU294 |
| A | ASP295 |
| A | PHE296 |
| A | ILE302 |
| A | CPS402 |
| A | GOL406 |
| A | HOH514 |
| A | HOH534 |
| A | GLY38 |
| A | HOH631 |
| A | ASN78 |
| A | TYR79 |
| A | VAL80 |
| A | SER81 |
| A | LEU133 |
| A | ASP216 |
| A | GLY218 |
| site_id | AC2 |
| Number of Residues | 16 |
| Details | binding site for residue CPS A 402 |
| Chain | Residue |
| A | VAL80 |
| A | SER81 |
| A | GLY204 |
| A | PHE246 |
| A | SER254 |
| A | LYS255 |
| A | PRO257 |
| A | THR258 |
| A | GLU260 |
| A | ILE292 |
| A | LEU294 |
| A | 8VO401 |
| A | HOH509 |
| A | HOH525 |
| A | HOH558 |
| A | HOH668 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 403 |
| Chain | Residue |
| A | GLU181 |
| A | GLY182 |
| A | LYS328 |
| A | HOH626 |
| site_id | AC4 |
| Number of Residues | 9 |
| Details | binding site for residue GOL A 404 |
| Chain | Residue |
| A | ASN235 |
| A | LEU236 |
| A | ASP237 |
| A | LYS240 |
| A | HOH513 |
| A | HOH547 |
| A | HOH552 |
| A | HOH560 |
| A | HOH567 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 405 |
| Chain | Residue |
| A | LYS48 |
| A | TYR68 |
| A | LYS70 |
| A | HOH537 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 406 |
| Chain | Residue |
| A | GLY38 |
| A | TYR194 |
| A | ILE214 |
| A | 8VO401 |
| A | HOH507 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. FILDTGSANLWV |
| Chain | Residue | Details |
| A | PHE33-VAL44 | |
| A | CYS213-VAL224 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 307 |
| Details | Domain: {"description":"Peptidase A1","evidences":[{"source":"PROSITE-ProRule","id":"PRU01103","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU01103","evidenceCode":"ECO:0000255"}]} |
