Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 20 |
| Details | binding site for residue 8V9 A 401 |
| Chain | Residue |
| A | ILE34 |
| A | GLY218 |
| A | THR219 |
| A | SER220 |
| A | ILE292 |
| A | LEU294 |
| A | PHE296 |
| A | ILE302 |
| A | CPS402 |
| A | GOL403 |
| A | GOL404 |
| A | ASP36 |
| A | HOH502 |
| A | GLY38 |
| A | ASN78 |
| A | TYR79 |
| A | VAL80 |
| A | SER81 |
| A | LEU133 |
| A | ASP216 |
| site_id | AC2 |
| Number of Residues | 12 |
| Details | binding site for residue CPS A 402 |
| Chain | Residue |
| A | VAL80 |
| A | SER81 |
| A | THR116 |
| A | PHE246 |
| A | SER254 |
| A | LYS255 |
| A | 8V9401 |
| A | GOL404 |
| A | HOH501 |
| A | HOH543 |
| A | HOH570 |
| A | HOH631 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 403 |
| Chain | Residue |
| A | GLY38 |
| A | TYR194 |
| A | ILE214 |
| A | 8V9401 |
| A | HOH530 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 404 |
| Chain | Residue |
| A | LEU294 |
| A | ASP295 |
| A | PHE296 |
| A | PRO297 |
| A | 8V9401 |
| A | CPS402 |
| A | HOH507 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 405 |
| Chain | Residue |
| A | GLU177 |
| A | GLU177 |
| A | ARG178 |
| A | LYS328 |
| A | HOH591 |
| A | HOH593 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | binding site for residue PO4 A 406 |
| Chain | Residue |
| A | ASN235 |
| A | LEU236 |
| A | ASP237 |
| A | LYS240 |
| A | HOH517 |
| A | HOH521 |
| A | HOH524 |
| A | HOH526 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. FILDTGSANLWV |
| Chain | Residue | Details |
| A | PHE33-VAL44 | |
| A | CYS213-VAL224 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 307 |
| Details | Domain: {"description":"Peptidase A1","evidences":[{"source":"PROSITE-ProRule","id":"PRU01103","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU01103","evidenceCode":"ECO:0000255"}]} |
