Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008757 | molecular_function | S-adenosylmethionine-dependent methyltransferase activity |
| B | 0008757 | molecular_function | S-adenosylmethionine-dependent methyltransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 22 |
| Details | binding site for residue SFG A 501 |
| Chain | Residue |
| A | GLN164 |
| A | GLY294 |
| A | ASP295 |
| A | PHE296 |
| A | CYS312 |
| A | PHE313 |
| A | PHE314 |
| A | THR317 |
| A | TYR324 |
| A | TYR386 |
| A | 8V0502 |
| A | ARG167 |
| A | ACT503 |
| A | HOH622 |
| A | HOH626 |
| A | TYR181 |
| A | GLY208 |
| A | ASN228 |
| A | GLU229 |
| A | TRP230 |
| A | SER231 |
| A | MET234 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | binding site for residue 8V0 A 502 |
| Chain | Residue |
| A | PHE313 |
| A | ASP316 |
| A | PRO343 |
| A | LEU345 |
| A | HIS347 |
| A | TYR386 |
| A | TYR396 |
| A | TYR398 |
| A | SFG501 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue ACT A 503 |
| Chain | Residue |
| A | LYS157 |
| A | SER231 |
| A | MET234 |
| A | SFG501 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 504 |
| Chain | Residue |
| A | GLN104 |
| A | PHE105 |
| A | SER266 |
| A | HOH629 |
| B | ASP363 |
| site_id | AC5 |
| Number of Residues | 22 |
| Details | binding site for residue SFG B 501 |
| Chain | Residue |
| B | GLN164 |
| B | ARG167 |
| B | TYR181 |
| B | GLY208 |
| B | ASN228 |
| B | GLU229 |
| B | TRP230 |
| B | SER231 |
| B | MET234 |
| B | GLY294 |
| B | ASP295 |
| B | PHE296 |
| B | CYS312 |
| B | PHE313 |
| B | PHE314 |
| B | THR317 |
| B | TYR324 |
| B | TYR386 |
| B | 8V0502 |
| B | HOH612 |
| B | HOH615 |
| B | HOH653 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | binding site for residue 8V0 B 502 |
| Chain | Residue |
| B | PHE313 |
| B | ASP316 |
| B | LEU345 |
| B | HIS347 |
| B | TYR386 |
| B | TYR396 |
| B | TYR398 |
| B | SFG501 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue CA B 503 |
| Chain | Residue |
| B | SER246 |
| B | SER246 |
| B | ASP279 |
| B | ASP279 |
| B | HOH733 |
| B | HOH733 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue CA B 504 |
| Chain | Residue |
| B | ASP110 |
| B | HOH654 |
| B | HOH744 |
| B | HOH809 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue ACT B 505 |
| Chain | Residue |
| B | LEU189 |
| B | LYS194 |
| B | PRO199 |
| B | LEU221 |
| B | TYR223 |
| B | HOH662 |
| site_id | AD1 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 506 |
| Chain | Residue |
| A | ARG265 |
| B | TYR361 |
| B | LYS365 |
| B | GLU378 |
| site_id | AD2 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 507 |
| Chain | Residue |
| A | ASP363 |
| B | GLN104 |
| B | PHE105 |
| B | SER266 |
| B | HOH655 |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | GLN164 | |
| B | ARG167 | |
| B | GLY208 | |
| B | GLU229 | |
| B | ASP295 | |
| B | PHE296 | |
| B | CYS312 | |
| B | TYR324 | |
| A | ARG167 | |
| A | GLY208 | |
| A | GLU229 | |
| A | ASP295 | |
| A | PHE296 | |
| A | CYS312 | |
| A | TYR324 | |
| B | GLN164 | |
| Chain | Residue | Details |
| A | ASP316 | |
| A | HIS347 | |
| A | TYR398 | |
| B | ASP316 | |
| B | HIS347 | |
| B | TYR398 | |
