Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008757 | molecular_function | S-adenosylmethionine-dependent methyltransferase activity |
| B | 0008757 | molecular_function | S-adenosylmethionine-dependent methyltransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 501 |
| Chain | Residue |
| A | ASP363 |
| B | PHE105 |
| B | SER266 |
| B | HOH687 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 502 |
| Chain | Residue |
| A | GLN297 |
| A | ASP323 |
| A | ASP326 |
| A | THR327 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 503 |
| Chain | Residue |
| A | GLN99 |
| A | LEU102 |
| A | PRO103 |
| A | LEU106 |
| A | HOH690 |
| A | PHE91 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue ACT A 504 |
| Chain | Residue |
| A | VAL388 |
| A | ASN389 |
| A | LYS395 |
| A | TYR396 |
| A | HOH634 |
| A | HOH731 |
| site_id | AC5 |
| Number of Residues | 20 |
| Details | binding site for residue SAM A 505 |
| Chain | Residue |
| A | GLN164 |
| A | ARG167 |
| A | TYR181 |
| A | GLY208 |
| A | ASN228 |
| A | GLU229 |
| A | TRP230 |
| A | SER231 |
| A | MET234 |
| A | GLY294 |
| A | ASP295 |
| A | PHE296 |
| A | CYS312 |
| A | PHE313 |
| A | PHE314 |
| A | THR317 |
| A | TYR324 |
| A | TYR386 |
| A | HOH612 |
| A | HOH627 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 501 |
| Chain | Residue |
| A | PHE105 |
| A | SER266 |
| B | ASP363 |
| B | HOH640 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | binding site for residue ACT B 502 |
| Chain | Residue |
| B | VAL388 |
| B | ASN389 |
| B | LYS395 |
| B | TYR396 |
| B | HOH668 |
| B | HOH741 |
| B | HOH781 |
| site_id | AC8 |
| Number of Residues | 19 |
| Details | binding site for residue SAM B 503 |
| Chain | Residue |
| B | GLN164 |
| B | ARG167 |
| B | TYR181 |
| B | GLY208 |
| B | ASN228 |
| B | GLU229 |
| B | TRP230 |
| B | SER231 |
| B | MET234 |
| B | GLY294 |
| B | ASP295 |
| B | PHE296 |
| B | CYS312 |
| B | PHE313 |
| B | PHE314 |
| B | THR317 |
| B | TYR324 |
| B | TYR386 |
| B | HOH649 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue CA B 504 |
| Chain | Residue |
| B | SER246 |
| B | SER246 |
| B | ASP279 |
| B | ASP279 |
| B | HOH719 |
| B | HOH719 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for residue CA B 505 |
| Chain | Residue |
| B | ASP110 |
| B | HOH602 |
| B | HOH761 |
| B | HOH789 |
| B | HOH816 |
| B | HOH824 |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | GLN164 | |
| B | ARG167 | |
| B | GLY208 | |
| B | GLU229 | |
| B | ASP295 | |
| B | PHE296 | |
| B | CYS312 | |
| B | TYR324 | |
| A | ARG167 | |
| A | GLY208 | |
| A | GLU229 | |
| A | ASP295 | |
| A | PHE296 | |
| A | CYS312 | |
| A | TYR324 | |
| B | GLN164 | |
| Chain | Residue | Details |
| A | ASP316 | |
| A | HIS347 | |
| A | TYR398 | |
| B | ASP316 | |
| B | HIS347 | |
| B | TYR398 | |
