5YA0

Crystal structure of LsrK and HPr complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0005975	biological_process	carbohydrate metabolic process
A	0009372	biological_process	quorum sensing
A	0016301	molecular_function	kinase activity
A	0016310	biological_process	phosphorylation
A	0044010	biological_process	single-species biofilm formation
A	0071518	molecular_function	autoinducer-2 kinase activity
B	0005515	molecular_function	protein binding
B	0005737	cellular_component	cytoplasm
B	0005975	biological_process	carbohydrate metabolic process
B	0009372	biological_process	quorum sensing
B	0016301	molecular_function	kinase activity
B	0016310	biological_process	phosphorylation
B	0044010	biological_process	single-species biofilm formation
B	0071518	molecular_function	autoinducer-2 kinase activity
C	0004857	molecular_function	enzyme inhibitor activity
C	0005515	molecular_function	protein binding
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0008047	molecular_function	enzyme activator activity
C	0009401	biological_process	phosphoenolpyruvate-dependent sugar phosphotransferase system
C	0016775	molecular_function	phosphotransferase activity, nitrogenous group as acceptor
C	0030234	molecular_function	enzyme regulator activity
C	0043609	biological_process	regulation of carbon utilization
C	0045152	molecular_function	antisigma factor binding
C	0045819	biological_process	positive regulation of glycogen catabolic process
D	0004857	molecular_function	enzyme inhibitor activity
D	0005515	molecular_function	protein binding
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0008047	molecular_function	enzyme activator activity
D	0009401	biological_process	phosphoenolpyruvate-dependent sugar phosphotransferase system
D	0016775	molecular_function	phosphotransferase activity, nitrogenous group as acceptor
D	0030234	molecular_function	enzyme regulator activity
D	0043609	biological_process	regulation of carbon utilization
D	0045152	molecular_function	antisigma factor binding
D	0045819	biological_process	positive regulation of glycogen catabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	binding site for residue HEZ A 801

Chain	Residue
A	HIS127
A	PHE131
A	GLU134
A	ALA206
A	MET210
C	ALA20
C	LEU47
C	PO4102

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site_id	AC2
Number of Residues	5
Details	binding site for residue PO4 A 802

Chain	Residue
A	LYS204
B	ARG137
B	ASP197
B	LYS204
A	ASP197

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site_id	AC3
Number of Residues	6
Details	binding site for residue HEZ B 601

Chain	Residue
B	HIS127
B	PHE131
B	GLU134
B	MET210
D	ALA20
D	PO4102

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site_id	AC4
Number of Residues	2
Details	binding site for residue PO4 B 602

Chain	Residue
A	LYS204
B	LYS204

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site_id	AC5
Number of Residues	2
Details	binding site for residue PO4 C 101

Chain	Residue
C	ASN38
C	LYS40

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site_id	AC6
Number of Residues	4
Details	binding site for residue PO4 C 102

Chain	Residue
A	HIS127
A	HEZ801
C	LYS24
C	LYS27

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site_id	AC7
Number of Residues	1
Details	binding site for residue PO4 D 101

Chain	Residue
D	ASN38

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site_id	AC8
Number of Residues	4
Details	binding site for residue PO4 D 102

Chain	Residue
B	HIS127
B	HEZ601
D	LYS24
D	LYS27

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Functional Information from PROSITE/UniProt

site_id	PS00369
Number of Residues	8
Details	PTS_HPR_HIS PTS HPR domain histidine phosphorylation site signature. GLHTRPAA

Chain	Residue	Details
C	GLY13-ALA20

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site_id	PS00589
Number of Residues	16
Details	PTS_HPR_SER PTS HPR domain serine phosphorylation site signature. GKsASaKSLFKLQtLG

Chain	Residue	Details
C	GLY39-GLY54

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE: Pros-phosphohistidine intermediate => ECO:0000255|PROSITE-ProRule:PRU00681, ECO:0000269|PubMed:2261470

Chain	Residue	Details
C	HIS15
D	HIS15

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