5Y7Y
Crystal structure of AhRR/ARNT complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| A | 0006805 | biological_process | xenobiotic metabolic process |
| A | 0009410 | biological_process | response to xenobiotic stimulus |
| A | 0046983 | molecular_function | protein dimerization activity |
| B | 0003700 | molecular_function | DNA-binding transcription factor activity |
| B | 0005634 | cellular_component | nucleus |
| B | 0005667 | cellular_component | transcription regulator complex |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
| B | 0046983 | molecular_function | protein dimerization activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 301 |
| Chain | Residue |
| A | SER131 |
| A | GLU133 |
| A | THR135 |
| A | PHE137 |
| A | GLN254 |
| A | LYS256 |
| A | HOH406 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 302 |
| Chain | Residue |
| A | PHE239 |
| B | ARG434 |
| A | ARG230 |
| A | SER237 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue GOL B 501 |
| Chain | Residue |
| A | PHE149 |
| A | ASP161 |
| A | ARG230 |
| B | LYS394 |
| B | GLU398 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 39 |
| Details | Region: {"description":"Helix-loop-helix motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU00981","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Region: {"description":"Mediates the transcription activity and dimerization of the AHR:ARNT complex","evidences":[{"source":"UniProtKB","id":"P53762","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
