5Y6N

Zika virus helicase in complex with ADP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004386	molecular_function	helicase activity
A	0005524	molecular_function	ATP binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue MN A 701

Chain	Residue
A	THR201
A	GLU286
A	ADP702
A	HOH846
A	HOH849
A	HOH854

---

site_id	AC2
Number of Residues	16
Details	binding site for residue ADP A 702

Chain	Residue
A	LYS200
A	THR201
A	ARG202
A	ASN330
A	ARG462
A	MN701
A	HOH846
A	HOH854
A	HOH878
A	HOH881
A	HOH979
A	HOH1024
A	HOH1032
A	GLY197
A	ALA198
A	GLY199

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI2
Number of Residues	3
Details	Region: {"description":"Important for RNA-binding","evidences":[{"source":"UniProtKB","id":"P14340","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	3
Details	Motif: {"description":"DEAH box","evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	7
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	2
Details	Site: {"description":"Involved in NS3 ATPase and RTPase activities","evidences":[{"source":"UniProtKB","id":"P14335","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine; by host","evidences":[{"source":"UniProtKB","id":"Q32ZE1","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---