5Y3D

Structural insight into the interaction between RNA polymerase and VPg for norovirus replication

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003723	molecular_function	RNA binding
A	0003968	molecular_function	RNA-dependent RNA polymerase activity
A	0004386	molecular_function	helicase activity
A	0005524	molecular_function	ATP binding
A	0006351	biological_process	DNA-templated transcription
A	0039694	biological_process	viral RNA genome replication
B	0003723	molecular_function	RNA binding
B	0003968	molecular_function	RNA-dependent RNA polymerase activity
B	0004386	molecular_function	helicase activity
B	0005524	molecular_function	ATP binding
B	0006351	biological_process	DNA-templated transcription
B	0039694	biological_process	viral RNA genome replication
C	0003723	molecular_function	RNA binding
C	0003968	molecular_function	RNA-dependent RNA polymerase activity
C	0004386	molecular_function	helicase activity
C	0005524	molecular_function	ATP binding
C	0006351	biological_process	DNA-templated transcription
C	0039694	biological_process	viral RNA genome replication
D	0003723	molecular_function	RNA binding
D	0003968	molecular_function	RNA-dependent RNA polymerase activity
D	0004386	molecular_function	helicase activity
D	0005524	molecular_function	ATP binding
D	0006351	biological_process	DNA-templated transcription
D	0039694	biological_process	viral RNA genome replication
E	0003723	molecular_function	RNA binding
E	0003968	molecular_function	RNA-dependent RNA polymerase activity
E	0004386	molecular_function	helicase activity
E	0005524	molecular_function	ATP binding
E	0006351	biological_process	DNA-templated transcription
E	0039694	biological_process	viral RNA genome replication
F	0003723	molecular_function	RNA binding
F	0003968	molecular_function	RNA-dependent RNA polymerase activity
F	0004386	molecular_function	helicase activity
F	0005524	molecular_function	ATP binding
F	0006351	biological_process	DNA-templated transcription
F	0039694	biological_process	viral RNA genome replication

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	BINDING: BINDING => ECO:0000269|PubMed:21471315, ECO:0000269|PubMed:22341781, ECO:0000269|PubMed:24622391

Chain	Residue	Details
A	ASP243
E	GLU348
F	ASP243
F	GLU348
A	GLU348
B	ASP243
B	GLU348
C	ASP243
C	GLU348
D	ASP243
D	GLU348
E	ASP243

---

site_id	SWS_FT_FI2
Number of Residues	6
Details	BINDING: BINDING => ECO:0000269|PubMed:21471315

Chain	Residue	Details
A	ASP245
B	ASP245
C	ASP245
D	ASP245
E	ASP245
F	ASP245

---

site_id	SWS_FT_FI3
Number of Residues	6
Details	BINDING: BINDING => ECO:0000269|PubMed:21471315, ECO:0000269|PubMed:24622391

Chain	Residue	Details
A	ASP347
B	ASP347
C	ASP347
D	ASP347
E	ASP347
F	ASP347

---

site_id	SWS_FT_FI4
Number of Residues	6
Details	BINDING: BINDING => ECO:0000269|PubMed:22341781, ECO:0000269|PubMed:24622391

Chain	Residue	Details
A	SER392
B	SER392
C	SER392
D	SER392
E	SER392
F	SER392

---